Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	ADRB1	[11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy	D00378	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
2	ADRB1	[11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy	D00603 (Name: TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
3	ADRB1	[11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy	D08600	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
4	ADRB2	[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation	D00378	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
5	ADRB2	[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation	D00603 (Name: TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
6	ADRB2	[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation	D08600	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
7	DDC	[9] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism	D00558 (Name: CARBIDOPA TABLETS, 25 MG)	Carbidopa (Synonym:CARBIDOPA TABLETS, 25 MG)	[9] 2, 4, 6, 13, 17, 90, 140, 164, 201
8	AGTR1	[16] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease - COVID-19, Pathways in cancer, Diabetic cardiomyopathy	D00357 (Name: LOSARTAN POTASSIUM TABLETS, 25 MG)	Losartan (Synonym:LOSARTAN POTASSIUM TABLETS, 25 MG)	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
9	AGTR1	[16] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease - COVID-19, Pathways in cancer, Diabetic cardiomyopathy	D08146	Losartan (Synonym:LOSARTAN POTASSIUM TABLETS, 25 MG)	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
10	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis	D01441	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
11	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis	D03252	Bosutinib	[2] 2, 67
12	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis	D03658	Dasatinib	[2] 51, 85
13	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis	D06414	Dasatinib	[2] 51, 85
14	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis	D08066	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
15	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis	D08953	Nilotinib	[5] 6, 8, 34, 51, 86
16	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Chronic myeloid leukemia, Viral myocarditis	D09664	Saracatinib	[3] 6, 89, 272
17	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes	D00903	Diclofenac (Synonym:DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)	[5] 13, 34, 46, 78, 271
18	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes	D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)	Diclofenac (Synonym:DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)	[5] 13, 34, 46, 78, 271
19	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes	D07816	Diclofenac (Synonym:DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)	[5] 13, 34, 46, 78, 271
20	PTGS2	[22] Arachidonic acid metabolism, Metabolic pathways, NF-kappa B signaling pathway, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer	D00903	Diclofenac (Synonym:DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)	[5] 13, 34, 46, 78, 271
21	PTGS2	[22] Arachidonic acid metabolism, Metabolic pathways, NF-kappa B signaling pathway, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer	D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)	Diclofenac (Synonym:DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)	[5] 13, 34, 46, 78, 271
22	PTGS2	[22] Arachidonic acid metabolism, Metabolic pathways, NF-kappa B signaling pathway, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer	D07816	Diclofenac (Synonym:DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)	[5] 13, 34, 46, 78, 271
23	SNAP25 (Full name: synaptosome associated protein 25)	[2] Synaptic vesicle cycle, Insulin secretion	D00783	Botulinum toxin type A	[13] 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226
24	SNAP25 (Full name: synaptosome associated protein 25)	[2] Synaptic vesicle cycle, Insulin secretion	D02735	Botulinum toxin type B	[4] 2, 6, 13, 51