Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	ADRB1	[11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive liga ...	D00378	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
2	ADRB1	[11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive liga ...	D00603 (Name: TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
3	ADRB1	[11] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive liga ...	D08600	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
4	ADRB2	[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D00378	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
5	ADRB2	[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D00603 (Name: TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
6	ADRB2	[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...	D08600	Timolol (Synonym:TIMOLOL MALEATE OPHTHALMIC GEL FORMING SOLUTION, 0.25%)	[2] 157, 227
7	DDC	[9] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Seroto ...	D00558 (Name: CARBIDOPA TABLETS, 25 MG)	Carbidopa (Synonym:CARBIDOPA TABLETS, 25 MG)	[9] 2, 4, 6, 13, 17, 90, 140, 164, 201
8	AGTR1	[16] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00357 (Name: LOSARTAN POTASSIUM TABLETS, 25 MG)	Losartan (Synonym:LOSARTAN POTASSIUM TABLETS, 25 MG)	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
9	AGTR1	[16] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D08146	Losartan (Synonym:LOSARTAN POTASSIUM TABLETS, 25 MG)	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
10	ABL1	[11] ErbB signaling pathway, Ras signaling pathway, Cell cycle, Axon guidance, Neurotrophin signalin ...	D01441	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162

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