Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00225	Alprazolam	[2] 8, 75
2	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00267	Chlordiazepoxide	[1] 46
3	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00280	Clonazepam	[1] 6
4	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00293	Diazepam	[3] 46, 155, 298
5	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00365	Lorazepam	[2] 36, 231
6	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00537	Topiramate	[6] 6, 97, 140, 144, 156, 193
7	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00548	Etomidate	[1] 6
8	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00549	Propofol	[10] 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
9	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00550	Midazolam	[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
10	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00693	Chlordiazepoxide	[1] 46

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