Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	FDPS	[1] Terpenoid backbone biosynthesis	D00939	Alendronic acid	[7] 19, 41, 46, 50, 271, 274, 299
2	FDPS	[1] Terpenoid backbone biosynthesis	D00941	Pamidronic acid	[3] 270, 271, 274
3	FDPS	[1] Terpenoid backbone biosynthesis	D00942	Risedronic acid	[9] 46, 50, 66, 93, 95, 96, 107, 113, 274
4	FDPS	[1] Terpenoid backbone biosynthesis	D01968	Zoledronic acid	[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
5	FDPS	[1] Terpenoid backbone biosynthesis	D03234	Risedronic acid	[9] 46, 50, 66, 93, 95, 96, 107, 113, 274
6	FDPS	[1] Terpenoid backbone biosynthesis	D06378	Zoledronic acid	[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
7	FDPS	[1] Terpenoid backbone biosynthesis	D06379	Zoledronic acid	[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
8	FDPS	[1] Terpenoid backbone biosynthesis	D07119	Alendronic acid	[7] 19, 41, 46, 50, 271, 274, 299
9	FDPS	[1] Terpenoid backbone biosynthesis	D07281	Pamidronic acid	[3] 270, 271, 274
10	FDPS	[1] Terpenoid backbone biosynthesis	D08056	Ibandronate	[3] 46, 49, 274

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