Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 NQO1 [7] Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis D00564 Warfarin [13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
2 NQO1 [7] Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis D01280 Warfarin [13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
3 NQO1 [7] Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis D08682 Warfarin [13] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97
4 NCSTN [2] Notch signaling pathway, Alzheimer disease D09010 Tarenflurbil [1] 13
5 NR3C1 [1] Neuroactive ligand-receptor interaction D00088 Hydrocortisone [11] 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
6 NR3C1 [1] Neuroactive ligand-receptor interaction D00165 Hydrocortisone acetate [1] 97
7 NR3C1 [1] Neuroactive ligand-receptor interaction D00244 Betamethasone [7] 2, 28, 46, 83, 90, 96, 235
8 NR3C1 [1] Neuroactive ligand-receptor interaction D00246 Budesonide [9] 66, 93, 94, 95, 96, 97, 98, 228, 299
9 NR3C1 [1] Neuroactive ligand-receptor interaction D00292 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
10 NR3C1 [1] Neuroactive ligand-receptor interaction D00385 Triamcinolone [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
11 NR3C1 [1] Neuroactive ligand-receptor interaction D00407 Methylprednisolone [48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
12 NR3C1 [1] Neuroactive ligand-receptor interaction D00472 Prednisolone [43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
13 NR3C1 [1] Neuroactive ligand-receptor interaction D00473 Prednisone [48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
14 NR3C1 [1] Neuroactive ligand-receptor interaction D00585 Mifepristone [1] 75
15 NR3C1 [1] Neuroactive ligand-receptor interaction D00689 Beclomethasone dipropionate [3] 85, 97, 98
16 NR3C1 [1] Neuroactive ligand-receptor interaction D00690 Mometasone [2] 98, 162
17 NR3C1 [1] Neuroactive ligand-receptor interaction D00690 Mometasone furoate [2] 98, 162
18 NR3C1 [1] Neuroactive ligand-receptor interaction D00751 Methylprednisolone [48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
19 NR3C1 [1] Neuroactive ligand-receptor interaction D00972 Betamethasone [7] 2, 28, 46, 83, 90, 96, 235
20 NR3C1 [1] Neuroactive ligand-receptor interaction D00973 Cortisone acetate [1] 81
21 NR3C1 [1] Neuroactive ligand-receptor interaction D00975 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
22 NR3C1 [1] Neuroactive ligand-receptor interaction D00976 Hydrocortisone cypionate [3] 6, 81, 83
23 NR3C1 [1] Neuroactive ligand-receptor interaction D00979 Methylprednisolone [48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
24 NR3C1 [1] Neuroactive ligand-receptor interaction D00980 Prednisolone [43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
25 NR3C1 [1] Neuroactive ligand-receptor interaction D00980 Prednisolone acetate [1] 222
26 NR3C1 [1] Neuroactive ligand-receptor interaction D00981 Prednisolone [43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
27 NR3C1 [1] Neuroactive ligand-receptor interaction D00982 Prednisolone [43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
28 NR3C1 [1] Neuroactive ligand-receptor interaction D00983 Triamcinolone [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
29 NR3C1 [1] Neuroactive ligand-receptor interaction D00984 Triamcinolone [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
30 NR3C1 [1] Neuroactive ligand-receptor interaction D00985 Triamcinolone [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
31 NR3C1 [1] Neuroactive ligand-receptor interaction D01239 Prednisolone [43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
32 NR3C1 [1] Neuroactive ligand-receptor interaction D01272 Clobetasol propionate [2] 46, 162
33 NR3C1 [1] Neuroactive ligand-receptor interaction D01357 Betamethasone [7] 2, 28, 46, 83, 90, 96, 235
34 NR3C1 [1] Neuroactive ligand-receptor interaction D01402 Betamethasone [7] 2, 28, 46, 83, 90, 96, 235
35 NR3C1 [1] Neuroactive ligand-receptor interaction D01442 Hydrocortisone succinate [3] 6, 81, 83
36 NR3C1 [1] Neuroactive ligand-receptor interaction D01510 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
37 NR3C1 [1] Neuroactive ligand-receptor interaction D01615 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
38 NR3C1 [1] Neuroactive ligand-receptor interaction D01632 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
39 NR3C1 [1] Neuroactive ligand-receptor interaction D01637 Betamethasone [7] 2, 28, 46, 83, 90, 96, 235
40 NR3C1 [1] Neuroactive ligand-receptor interaction D01703 Ciclesonide [1] 84
41 NR3C1 [1] Neuroactive ligand-receptor interaction D01708 Fluticasone propionate [2] 98, 228
42 NR3C1 [1] Neuroactive ligand-receptor interaction D01825 Fluocinolone acetonide [1] 90
43 NR3C1 [1] Neuroactive ligand-receptor interaction D01948 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
44 NR3C1 [1] Neuroactive ligand-receptor interaction D01998 Prednisolone [43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
45 NR3C1 [1] Neuroactive ligand-receptor interaction D02032 Betamethasone [7] 2, 28, 46, 83, 90, 96, 235
46 NR3C1 [1] Neuroactive ligand-receptor interaction D02156 Prednisolone [43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
47 NR3C1 [1] Neuroactive ligand-receptor interaction D02174 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
48 NR3C1 [1] Neuroactive ligand-receptor interaction D02286 Betamethasone [7] 2, 28, 46, 83, 90, 96, 235
49 NR3C1 [1] Neuroactive ligand-receptor interaction D02591 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
50 NR3C1 [1] Neuroactive ligand-receptor interaction D02592 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
51 NR3C1 [1] Neuroactive ligand-receptor interaction D03301 Prednisolone [43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
52 NR3C1 [1] Neuroactive ligand-receptor interaction D03325 Mometasone [2] 98, 162
53 NR3C1 [1] Neuroactive ligand-receptor interaction D03671 Deflazacort [2] 30, 113
54 NR3C1 [1] Neuroactive ligand-receptor interaction D05000 Methylprednisolone [48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
55 NR3C1 [1] Neuroactive ligand-receptor interaction D05000 Methylprednisolone hemisuccinate [7] 13, 49, 50, 51, 53, 97, 211
56 NR3C1 [1] Neuroactive ligand-receptor interaction D05001 Methylprednisolone [48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
57 NR3C1 [1] Neuroactive ligand-receptor interaction D05002 Methylprednisolone [48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
58 NR3C1 [1] Neuroactive ligand-receptor interaction D06216 Triamcinolone [10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
59 NR3C1 [1] Neuroactive ligand-receptor interaction D07202 Halometasone [1] 162
60 NR3C1 [1] Neuroactive ligand-receptor interaction D07495 Beclomethasone dipropionate [3] 85, 97, 98
61 NR3C1 [1] Neuroactive ligand-receptor interaction D07715 Clobetasol propionate [2] 46, 162
62 NR3C1 [1] Neuroactive ligand-receptor interaction D07715 Clobetasol [4] 39, 46, 51, 162
63 NR3C1 [1] Neuroactive ligand-receptor interaction D07749 Cortisone [1] 81
64 NR3C1 [1] Neuroactive ligand-receptor interaction D07981 Fluticasone [3] 98, 228, 299
65 NR3C1 [1] Neuroactive ligand-receptor interaction D08227 Mometasone [2] 98, 162
66 NR3C1 [1] Neuroactive ligand-receptor interaction D08416 Prednisone acetate [7] 35, 40, 41, 46, 49, 162, 224
67 NR3C1 [1] Neuroactive ligand-receptor interaction D11000 Vamorolone [2] 97, 113
68 NR3C1 [1] Neuroactive ligand-receptor interaction D11336 Relacorilant [1] 75
69 NPC1L1 [1] Fat digestion and absorption D01966 Ezetimibe [4] 49, 79, 93, 260
70 NR3C2 [1] Aldosterone-regulated sodium reabsorption D00443 Spironolactone [7] 58, 67, 86, 113, 210, 218, 225
71 NR3C2 [1] Aldosterone-regulated sodium reabsorption D00986 Fludrocortisone [3] 6, 17, 81
72 NR3C2 [1] Aldosterone-regulated sodium reabsorption D01115 Eplerenone [4] 75, 113, 210, 215
73 NR3C2 [1] Aldosterone-regulated sodium reabsorption D07967 Fludrocortisone [3] 6, 17, 81
74 NR3C2 [1] Aldosterone-regulated sodium reabsorption D10528 Aldosterone [1] 222
75 NFE2L2 [7] Protein processing in endoplasmic reticulum, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D10964 Omaveloxolone [1] 18
76 NFKB1 [76] Antifolate resistance, MAPK signaling pathway, Ras signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, NF-kappa B signaling pathway, HIF-1 signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Longevity regulating pathway, Cellular senescence, Osteoclast differentiation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Cytosolic DNA-sensing pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, TNF signaling pathway, Neurotrophin signaling pathway, Prolactin signaling pathway, Adipocytokine signaling pathway, Relaxin signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Pancreatic cancer, Prostate cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D01146 Iguratimod [4] 46, 51, 53, 271
77 NGF [9] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis, Neurotrophin signaling pathway, Inflammatory mediator regulation of TRP channels D09387 Tanezumab [2] 226, 298
78 NGFR [8] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis - multiple species, Neurotrophin signaling pathway, Transcriptional misregulation in cancer D11028 Cenegermin [2] 53, 90
79 NPR1 [10] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion D04051 Erythrityl tetranitrate [1] 46
80 NPR1 [10] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion D05147 Nesiritide [2] 46, 58
81 NPR2 [5] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Oxytocin signaling pathway D04051 Erythrityl tetranitrate [1] 46
82 NPR2 [5] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Oxytocin signaling pathway D11190 Vosoritide [1] 276
83 NR1H4 [1] Bile secretion D00163 Chenodeoxycholic acid [4] 20, 96, 234, 263
84 NR1H4 [1] Bile secretion D00734 Ursodeoxycholic acid [14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299
85 NR1H4 [1] Bile secretion D09360 Obeticholic acid [3] 93, 265, 296
86 NR1H4 [1] Bile secretion D10699 Cholic Acid [4] 20, 234, 265, 310
87 NR1H4 [1] Bile secretion D11548 Tropifexor [1] 93