Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Apelin signaling pathway 💬	[1] PDE3B 💬	D00417 💬	Milrinone	[1] 294 💬
2	Apelin signaling pathway 💬	[1] PDE3B 💬	D02085 💬	Milrinone	[1] 294 💬
3	cAMP signaling pathway 💬	[2] PDE3A, PDE3B 💬	D00417 💬	Milrinone	[1] 294 💬
4	cAMP signaling pathway 💬	[2] PDE3A, PDE3B 💬	D02085 💬	Milrinone	[1] 294 💬
5	cGMP-PKG signaling pathway 💬	[2] PDE3A, PDE3B 💬	D00417 💬	Milrinone	[1] 294 💬
6	cGMP-PKG signaling pathway 💬	[2] PDE3A, PDE3B 💬	D02085 💬	Milrinone	[1] 294 💬
7	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D02229 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
8	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D08514 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
9	Collecting duct acid secretion 💬	[2] ATP4A, ATP4B 💬	D00455 💬	Omeprazole	[16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
10	Collecting duct acid secretion 💬	[2] ATP4A, ATP4B 💬	D01207 💬	Omeprazole	[16] 6 , 8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬

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