Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
2	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
3	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00615 💬	Amlodipine	[4] 13, 51, 67, 298 💬
4	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02914 💬	Amlodipine	[4] 13, 51, 67, 298 💬
5	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07450 💬	Amlodipine	[4] 13, 51, 67, 298 💬
6	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬	D00332 💬	Gabapentin	[5] 6 , 13, 19, 70, 298 💬
7	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬	D02716 💬	Pregabalin	[5] 13, 36, 46, 70, 298 💬
8	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D01450 💬	Bupivacaine	[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
9	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D07552 💬	Bupivacaine	[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
10	African trypanosomiasis 💬	[1] TNF 💬	D00742 💬	Etanercept	[17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬

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