Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] KIT 💬	D10229 💬	Masitinib	[6] 2 , 5 , 6 , 13, 46, 96 💬
2	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D01277 💬	Droxidopa	[5] 5 , 6 , 17, 169, 170 💬
3	Alanine, aspartate and glutamate metabolism 💬	[4] ABAT, ALDH5A1, GAD1, GAD2 💬	D00399 💬	Valproic acid	[17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
4	Alcoholism 💬	[2] DRD1, DRD2 💬	D02004 💬	Apomorphine	[3] 5 , 6 , 7 💬
5	Alcoholism 💬	[2] DRD1, DRD2 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
6	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	[9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
7	Alcoholism 💬	[1] MAOB 💬	D02562 💬	Rasagiline	[7] 2 , 5 , 6 , 13, 17, 58, 66 💬
8	Alcoholism 💬	[1] MAOB 💬	D08469 💬	Rasagiline	[7] 2 , 5 , 6 , 13, 17, 58, 66 💬
9	Alcoholism 💬	[1] MAOB 💬	D10829 💬	Rasagiline	[7] 2 , 5 , 6 , 13, 17, 58, 66 💬
10	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D00399 💬	Valproic acid	[17] 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬

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