Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Aldosterone-regulated sodium reabsorption 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	D00297 💬	Digitoxin	[1] 299 💬
2	Aldosterone-regulated sodium reabsorption 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	D00298 💬	Digoxin	[3] 8 , 46, 210 💬
3	Aldosterone-regulated sodium reabsorption 💬	[1] INSR 💬	D04539 💬	Insulin detemir	[1] 299 💬
4	Aldosterone-regulated sodium reabsorption 💬	[1] INSR 💬	D03250 💬	Insulin glargine	[1] 299 💬
5	Aldosterone-regulated sodium reabsorption 💬	[1] INSR 💬	D00085 💬	Insulin human	[2] 96, 156 💬
6	Aldosterone-regulated sodium reabsorption 💬	[1] INSR 💬	D03230 💬	Insulin human	[2] 96, 156 💬
7	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D10528 💬	Aldosterone	[1] 222 💬
8	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D01115 💬	Eplerenone	[4] 75, 113, 210, 215 💬
9	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D00986 💬	Fludrocortisone	[3] 6 , 17, 81 💬
10	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D07967 💬	Fludrocortisone	[3] 6 , 17, 81 💬

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