Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Calcium signaling pathway 💬	[1] ADORA2A 💬	D04641 💬	Istradefylline	[1] 6 💬
2	Calcium signaling pathway 💬	[1] ADORA2A 💬	D09717 💬	Preladenant	[1] 6 💬
3	Calcium signaling pathway 💬	[1] ADORA2A 💬	D05711 💬	Regadenoson	[1] 58 💬
4	Calcium signaling pathway 💬	[1] ADORA2A 💬	D10174 💬	Tozadenant	[1] 6 💬
5	Calcium signaling pathway 💬	[2] ADORA2A, ADORA2B 💬	D00045 💬	Adenosine	[3] 13, 58, 65 💬
6	Calcium signaling pathway 💬	[2] ADORA2A, ADORA2B 💬	D02769 💬	Adenosine phosphate	[1] 46 💬
7	Calcium signaling pathway 💬	[4] ADORA2A, PDE1A, PDE1B, PDE1C 💬	D02017 💬	Theophylline	[2] 236, 299 💬
8	Calcium signaling pathway 💬	[2] ADORA2A, PDE1B 💬	D00528 💬	Caffeine	[9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬
9	Calcium signaling pathway 💬	[2] ADORA2A, PDE1B 💬	D01453 💬	Caffeine	[9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬
10	Calcium signaling pathway 💬	[4] ADORA2B, PDE1A, PDE1B, PDE1C 💬	D00227 💬	Aminophylline	[1] 63 💬

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