Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adipocytokine signaling pathway 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
2 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D00608 💬 Doxazosin [2] 57, 67 💬
3 Adrenergic signaling in cardiomyocytes 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D07874 💬 Doxazosin [2] 57, 67 💬
4 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
5 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
6 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
7 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
8 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
9 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
10 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
11 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
12 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
13 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
14 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
15 Alcoholic liver disease 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
16 Aldosterone synthesis and secretion 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
17 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
18 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
19 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00608 💬 Doxazosin [2] 57, 67 💬
20 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D07874 💬 Doxazosin [2] 57, 67 💬
21 Apelin signaling pathway 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
22 Caffeine metabolism 💬
 [1] XDH 💬 D00224 💬 Allopurinol [6]  6 , 46, 57, 66, 96, 97 💬
23 Calcium signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D00608 💬 Doxazosin [2] 57, 67 💬
24 Calcium signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D07874 💬 Doxazosin [2] 57, 67 💬
25 Calcium signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
26 Calcium signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
27 Calcium signaling pathway 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
28 Calcium signaling pathway 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
29 Calcium signaling pathway 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
30 Calcium signaling pathway 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
31 Calcium signaling pathway 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
32 Calcium signaling pathway 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
33 Calcium signaling pathway 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
34 Calcium signaling pathway 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
35 cAMP signaling pathway 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
36 cAMP signaling pathway 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
37 cAMP signaling pathway 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
38 cAMP signaling pathway 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
39 cAMP signaling pathway 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
40 cAMP signaling pathway 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
41 cAMP signaling pathway 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
42 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
43 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
44 cAMP signaling pathway 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
45 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D00608 💬 Doxazosin [2] 57, 67 💬
46 cGMP-PKG signaling pathway 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D07874 💬 Doxazosin [2] 57, 67 💬
47 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
48 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
49 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
50 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
51 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
52 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
53 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
54 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
55 cGMP-PKG signaling pathway 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
56 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
57 Chagas disease 💬
 [1] ACE 💬 D00620 💬 Benazepril [4] 49, 57, 218, 224 💬
58 Chagas disease 💬
 [1] ACE 💬 D07499 💬 Benazepril [4] 49, 57, 218, 224 💬
59 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
60 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
61 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
62 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
63 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
64 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
65 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
66 Chemical carcinogenesis - receptor activation 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
67 Chemical carcinogenesis - receptor activation 💬
 [2] ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
68 Chemical carcinogenesis - receptor activation 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
69 Coronavirus disease - COVID-19 💬
 [1] ACE 💬 D00620 💬 Benazepril [4] 49, 57, 218, 224 💬
70 Coronavirus disease - COVID-19 💬
 [1] ACE 💬 D07499 💬 Benazepril [4] 49, 57, 218, 224 💬
71 Coronavirus disease - COVID-19 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
72 Cortisol synthesis and secretion 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
73 Cushing syndrome 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
74 Cytokine-cytokine receptor interaction 💬
 [1] CSF3R 💬 D03235 💬 Filgrastim [34]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
75 Cytokine-cytokine receptor interaction 💬
 [1] CSF3R 💬 D03247 💬 Lenograstim [7]  2 , 13, 16, 18, 19, 57, 65 💬
76 Diabetic cardiomyopathy 💬
 [1] ACE 💬 D00620 💬 Benazepril [4] 49, 57, 218, 224 💬
77 Diabetic cardiomyopathy 💬
 [1] ACE 💬 D07499 💬 Benazepril [4] 49, 57, 218, 224 💬
78 Diabetic cardiomyopathy 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
79 Diabetic cardiomyopathy 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
80 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00636 💬 Amiodarone [2] 28, 127 💬
81 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
82 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00235 💬 Atenolol [1] 167 💬
83 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00634 💬 Bisoprolol [3] 67, 86, 113 💬
84 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [3] 67, 86, 113 💬
85 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
86 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
87 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D07660 💬 Celiprolol [1] 168 💬
88 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02349 💬 Dipivefrin [1]  6  💬
89 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
90 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
91 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
92 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
93 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
94 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00124 💬 Ephedrine [1] 11 💬
95 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00095 💬 Epinephrine [3] 46, 70, 96 💬
96 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00996 💬 Epinephrine [3] 46, 70, 96 💬
97 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02149 💬 Epinephrine [3] 46, 70, 96 💬
98 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00644 💬 Esmolol [1] 58 💬
99 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D07916 💬 Esmolol [1] 58 💬
100 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
101 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
102 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
103 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00432 💬 Nadolol [1]  6  💬
104 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05127 💬 Nebivolol [4] 17, 85, 113, 167 💬
105 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00076 💬 Norepinephrine [1] 22 💬
106 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05206 💬 Norepinephrine [1] 22 💬
107 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00483 💬 Propranolol [7]  6 , 158, 167, 215, 227, 278, 296 💬
108 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D08443 💬 Propranolol [7]  6 , 158, 167, 215, 227, 278, 296 💬
109 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00485 💬 Pseudoephedrine [1] 17 💬
110 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05648 💬 Pseudoephedrine [1] 17 💬
111 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05649 💬 Pseudoephedrine [1] 17 💬
112 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D08449 💬 Pseudoephedrine [1] 17 💬
113 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00378 💬 Timolol [2] 157, 227 💬
114 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00603 💬 Timolol [2] 157, 227 💬
115 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D08600 💬 Timolol [2] 157, 227 💬
116 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00615 💬 Amlodipine [4] 13, 51, 67, 298 💬
117 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02914 💬 Amlodipine [4] 13, 51, 67, 298 💬
118 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07450 💬 Amlodipine [4] 13, 51, 67, 298 💬
119 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01173 💬 Cilnidipine [1] 67 💬
120 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00616 💬 Diltiazem [3] 51, 58, 86 💬
121 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D03830 💬 Diltiazem [3] 51, 58, 86 💬
122 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
123 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00349 💬 Isradipine [1]  6  💬
124 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00617 💬 Nicardipine [2] 70, 86 💬
125 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
126 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00437 💬 Nifedipine [2] 50, 81 💬
127 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01908 💬 Nilvadipine [1] 90 💬
128 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D05442 💬 Perhexiline [2] 58, 272 💬
129 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08340 💬 Perhexiline [2] 58, 272 💬
130 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
131 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
132 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00619 💬 Verapamil [3] 96, 140, 167 💬
133 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02356 💬 Verapamil [3] 96, 140, 167 💬
134 Dilated cardiomyopathy 💬
 [2] CACNA2D1, CACNA2D2 💬 D11203 💬 Mirogabalin [1] 70 💬
135 Dilated cardiomyopathy 💬
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D00332 💬 Gabapentin [5]  6 , 13, 19, 70, 298 💬
136 Dilated cardiomyopathy 💬
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D02716 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
137 Dilated cardiomyopathy 💬
 [1] DMD 💬 D11988 💬 Casimersen [1] 113 💬
138 Dilated cardiomyopathy 💬
 [1] DMD 💬 D10114 💬 Drisapersen [1] 113 💬
139 Dilated cardiomyopathy 💬
 [1] DMD 💬 D09900 💬 Eteplirsen [1] 113 💬
140 Dilated cardiomyopathy 💬
 [1] DMD 💬 D11707 💬 Golodirsen [1] 113 💬
141 Dilated cardiomyopathy 💬
 [1] DMD 💬 D11528 💬 Viltolarsen [1] 113 💬
142 Dilated cardiomyopathy 💬
 [1] ITGA4 💬 D06590 💬 Firategrast [1] 13 💬
143 Dilated cardiomyopathy 💬
 [1] ITGA4 💬 D06886 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
144 Dilated cardiomyopathy 💬
 [2] ITGA4, ITGB7 💬 D10540 💬 Abrilumab [2] 96, 97 💬
145 Dilated cardiomyopathy 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
146 Dilated cardiomyopathy 💬
 [1] ITGB7 💬 D09901 💬 Etrolizumab [2] 96, 97 💬
147 Dilated cardiomyopathy 💬
 [1] MYH7 💬 D12265 💬 Mavacamten [1] 58 💬
148 Dilated cardiomyopathy 💬
 [3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [4] 51, 85, 222, 274 💬
149 Dilated cardiomyopathy 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
150 Dilated cardiomyopathy 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
151 Dilated cardiomyopathy 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
152 Dilated cardiomyopathy 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
153 Dilated cardiomyopathy 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
154 Dilated cardiomyopathy 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
155 Dilated cardiomyopathy 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
156 Dilated cardiomyopathy 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
157 Dilated cardiomyopathy 💬
 [1] TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
158 Dilated cardiomyopathy 💬
 [1] TNF 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
159 Dilated cardiomyopathy 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
160 Drug metabolism - other enzymes 💬
 [1] XDH 💬 D00224 💬 Allopurinol [6]  6 , 46, 57, 66, 96, 97 💬
161 Gap junction 💬
 [1] ADRB1 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
162 Gap junction 💬
 [1] ADRB1 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
163 Gap junction 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
164 Gap junction 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
165 Gap junction 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
166 Gap junction 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
167 Gap junction 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
168 Gap junction 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
169 Gap junction 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
170 Glucagon signaling pathway 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
171 Hematopoietic cell lineage 💬
 [1] CSF3R 💬 D03235 💬 Filgrastim [34]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
172 Hematopoietic cell lineage 💬
 [1] CSF3R 💬 D03247 💬 Lenograstim [7]  2 , 13, 16, 18, 19, 57, 65 💬
173 Hepatitis C 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
174 Hypertrophic cardiomyopathy 💬
 [1] ACE 💬 D00620 💬 Benazepril [4] 49, 57, 218, 224 💬
175 Hypertrophic cardiomyopathy 💬
 [1] ACE 💬 D07499 💬 Benazepril [4] 49, 57, 218, 224 💬
176 Insulin resistance 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
177 JAK-STAT signaling pathway 💬
 [1] CSF3R 💬 D03235 💬 Filgrastim [34]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
178 JAK-STAT signaling pathway 💬
 [1] CSF3R 💬 D03247 💬 Lenograstim [7]  2 , 13, 16, 18, 19, 57, 65 💬
179 Metabolic pathways 💬
 [1] XDH 💬 D00224 💬 Allopurinol [6]  6 , 46, 57, 66, 96, 97 💬
180 Neuroactive ligand-receptor interaction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D00608 💬 Doxazosin [2] 57, 67 💬
181 Neuroactive ligand-receptor interaction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D07874 💬 Doxazosin [2] 57, 67 💬
182 Neuroactive ligand-receptor interaction 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
183 Neuroactive ligand-receptor interaction 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
184 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
185 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
186 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
187 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
188 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
189 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
190 Neuroactive ligand-receptor interaction 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
191 Neuroactive ligand-receptor interaction 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
192 Non-alcoholic fatty liver disease 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
193 Pathways in cancer 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
194 Pathways in cancer 💬
 [1] CSF3R 💬 D03235 💬 Filgrastim [34]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
195 Pathways in cancer 💬
 [1] CSF3R 💬 D03247 💬 Lenograstim [7]  2 , 13, 16, 18, 19, 57, 65 💬
196 Peroxisome 💬
 [1] XDH 💬 D00224 💬 Allopurinol [6]  6 , 46, 57, 66, 96, 97 💬
197 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
198 PI3K-Akt signaling pathway 💬
 [1] CSF3R 💬 D03235 💬 Filgrastim [34]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
199 PI3K-Akt signaling pathway 💬
 [1] CSF3R 💬 D03247 💬 Lenograstim [7]  2 , 13, 16, 18, 19, 57, 65 💬
200 PPAR signaling pathway 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
201 Purine metabolism 💬
 [1] XDH 💬 D00224 💬 Allopurinol [6]  6 , 46, 57, 66, 96, 97 💬
202 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
203 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
204 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
205 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
206 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
207 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
208 Regulation of lipolysis in adipocytes 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
209 Regulation of lipolysis in adipocytes 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
210 Regulation of lipolysis in adipocytes 💬
 [2] ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
211 Renin secretion 💬
 [1] ACE 💬 D00620 💬 Benazepril [4] 49, 57, 218, 224 💬
212 Renin secretion 💬
 [1] ACE 💬 D07499 💬 Benazepril [4] 49, 57, 218, 224 💬
213 Renin secretion 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
214 Renin secretion 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
215 Renin secretion 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
216 Renin secretion 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
217 Renin secretion 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
218 Renin secretion 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
219 Renin secretion 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
220 Renin secretion 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
221 Renin secretion 💬
 [2] ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
222 Renin secretion 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
223 Renin-angiotensin system 💬
 [1] ACE 💬 D00620 💬 Benazepril [4] 49, 57, 218, 224 💬
224 Renin-angiotensin system 💬
 [1] ACE 💬 D07499 💬 Benazepril [4] 49, 57, 218, 224 💬
225 Renin-angiotensin system 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
226 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D00608 💬 Doxazosin [2] 57, 67 💬
227 Salivary secretion 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D07874 💬 Doxazosin [2] 57, 67 💬
228 Salivary secretion 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
229 Salivary secretion 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
230 Salivary secretion 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
231 Salivary secretion 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
232 Salivary secretion 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
233 Salivary secretion 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
234 Salivary secretion 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
235 Salivary secretion 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
236 Salivary secretion 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
237 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
238 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
239 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D00608 💬 Doxazosin [2] 57, 67 💬
240 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D07874 💬 Doxazosin [2] 57, 67 💬
241 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬

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