Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Longevity regulating pathway - multiple species 💬	[2] HDAC1, HDAC2 💬	D06320 💬	Vorinostat	[3] 19, 75, 96 💬
2	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬	D09925 💬	Linsitinib	[1] 232 💬
3	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬	D03297 💬	Mecasermin	[6] 65, 78, 96, 168, 265, 299 💬
4	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬	D04870 💬	Mecasermin	[6] 65, 78, 96, 168, 265, 299 💬
5	Longevity regulating pathway - multiple species 💬	[1] IGF1R 💬	D09680 💬	Teprotumumab	[1] 51 💬
6	Longevity regulating pathway - multiple species 💬	[1] INSR 💬	D04539 💬	Insulin detemir	[1] 299 💬
7	Longevity regulating pathway - multiple species 💬	[1] INSR 💬	D03250 💬	Insulin glargine	[1] 299 💬
8	Longevity regulating pathway - multiple species 💬	[1] INSR 💬	D00085 💬	Insulin human	[2] 96, 156 💬
9	Longevity regulating pathway - multiple species 💬	[1] INSR 💬	D03230 💬	Insulin human	[2] 96, 156 💬
10	Longevity regulating pathway - multiple species 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬

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