Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Prion disease 💬	[1] C5 💬	D11696 💬	Crovalimab	[2] 62, 109 💬
2	Prion disease 💬	[1] C5 💬	D03940 💬	Eculizumab	[7] 11, 13, 14, 61, 62, 109, 222 💬
3	Prion disease 💬	[1] C5 💬	D11473 💬	Nomacopan	[3] 62, 109, 162 💬
4	Prion disease 💬	[1] C5 💬	D11477 💬	Pozelimab	[2] 11, 62 💬
5	Prion disease 💬	[1] C5 💬	D11054 💬	Ravulizumab	[7] 2 , 11, 13, 50, 62, 66, 109 💬
6	Prion disease 💬	[1] C5 💬	D11838 💬	Vilobelimab	[3] 43, 44, 269 💬
7	Prion disease 💬	[5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D01173 💬	Cilnidipine	[1] 67 💬
8	Prion disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00615 💬	Amlodipine	[4] 13, 51, 67, 298 💬
9	Prion disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02914 💬	Amlodipine	[4] 13, 51, 67, 298 💬
10	Prion disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07450 💬	Amlodipine	[4] 13, 51, 67, 298 💬

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