Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Nitrogen metabolism 💬	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬	D00218 💬	Acetazolamide	[8] 13, 86, 90, 115, 154, 155, 225, 230 💬
2	Nitrogen metabolism 💬	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬	D01196 💬	Acetazolamide	[8] 13, 86, 90, 115, 154, 155, 225, 230 💬
3	Nitrogen metabolism 💬	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬	D00518 💬	Diclofenamide	[1] 114 💬
4	Nitrogen metabolism 💬	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬	D00653 💬	Dorzolamide	[1] 90 💬
5	Nitrogen metabolism 💬	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬	D07871 💬	Dorzolamide	[1] 90 💬
6	Nitrogen metabolism 💬	[2] CA2, CA4 💬	D00537 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬
7	Nitrogen metabolism 💬	[1] CPS1 💬	D07130 💬	Carglumic acid	[3] 245, 246, 251 💬

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