Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Metabolic pathways 💬
 [1] ABAT 💬 D00535 💬 Vigabatrin [2] 145, 158 💬
2 Metabolic pathways 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
3 Metabolic pathways 💬
 [1] ADA 💬 D11017 💬 Elapegademase [1] 65 💬
4 Metabolic pathways 💬
 [3] ADH1A, ADH1B, ADH1C 💬 D00707 💬 Fomepizole [1] 301 💬
5 Metabolic pathways 💬
 [1] ALAS1 💬 D11702 💬 Givosiran [1] 254 💬
6 Metabolic pathways 💬
 [2] ALAS1, ALAS2 💬 D10003 💬 Hemin [1] 254 💬
7 Metabolic pathways 💬
 [1] ALOX5 💬 D01773 💬 Oxatomide [1] 113 💬
8 Metabolic pathways 💬
 [1] ALOX5 💬 D00414 💬 Zileuton [3] 85, 160, 164 💬
9 Metabolic pathways 💬
 [1] ALPL 💬 D10595 💬 Asfotase alfa [1] 172 💬
10 Metabolic pathways 💬
 [5] AMY2A, AMY2B, GAA, GANC, MGAM 💬 D00216 💬 Acarbose [1] 298 💬
11 Metabolic pathways 💬
 [1] ANPEP 💬 D00087 💬 Ubenimex [1] 86 💬
12 Metabolic pathways 💬
 [1] AOC3 💬 D08044 💬 Hydralazine [1] 67 💬
13 Metabolic pathways 💬
 [1] ARSB 💬 D06565 💬 Galsulfase [1] 19 💬
14 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D08903 💬 Dexlansoprazole [1] 98 💬
15 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D01984 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
16 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D04056 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
17 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D07917 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
18 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D09339 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
19 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D00355 💬 Lansoprazole [7] 63, 71, 85, 98, 166, 222, 299 💬
20 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
21 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
22 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
23 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
24 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D02593 💬 Pantoprazole [2] 13, 65 💬
25 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D05353 💬 Pantoprazole [2] 13, 65 💬
26 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D00724 💬 Rabeprazole [2]  2 , 51 💬
27 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D08463 💬 Rabeprazole [2]  2 , 51 💬
28 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D11784 💬 Vonoprazan [2] 63, 98 💬
29 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
30 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
31 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00518 💬 Diclofenamide [1] 114 💬
32 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00653 💬 Dorzolamide [1] 90 💬
33 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D07871 💬 Dorzolamide [1] 90 💬
34 Metabolic pathways 💬
 [2] CA2, CA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
35 Metabolic pathways 💬
 [1] CD38 💬 D10777 💬 Daratumumab [5] 16, 28, 49, 63, 222 💬
36 Metabolic pathways 💬
 [1] CD38 💬 D11050 💬 Isatuximab [2] 28, 61 💬
37 Metabolic pathways 💬
 [1] CD38 💬 D11945 💬 Mezagitamab [1] 66 💬
38 Metabolic pathways 💬
 [1] COMT 💬 D00781 💬 Entacapone [2]  6 , 17 💬
39 Metabolic pathways 💬
 [1] COMT 💬 D10825 💬 Opicapone [1]  6  💬
40 Metabolic pathways 💬
 [1] COMT 💬 D00786 💬 Tolcapone [3]  6 , 28, 127 💬
41 Metabolic pathways 💬
 [1] CPS1 💬 D07130 💬 Carglumic acid [3] 245, 246, 251 💬
42 Metabolic pathways 💬
 [1] CYP11B1 💬 D00410 💬 Metyrapone [2] 75, 193 💬
43 Metabolic pathways 💬
 [1] CYP11B1 💬 D05019 💬 Metyrapone [2] 75, 193 💬
44 Metabolic pathways 💬
 [1] CYP11B2 💬 D11061 💬 Osilodrostat [1] 75 💬
45 Metabolic pathways 💬
 [1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
46 Metabolic pathways 💬
 [1] CYP19A1 💬 D00960 💬 Anastrozole [3] 78, 86, 193 💬
47 Metabolic pathways 💬
 [1] CYP19A1 💬 D00964 💬 Letrozole [2] 81, 89 💬
48 Metabolic pathways 💬
 [1] DDC 💬 D03082 💬 Benserazide [1]  6  💬
49 Metabolic pathways 💬
 [1] DDC 💬 D00558 💬 Carbidopa [9]  2 ,  4 ,  6 , 13, 17, 90, 140, 164, 201 💬
50 Metabolic pathways 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
51 Metabolic pathways 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
52 Metabolic pathways 💬
 [1] DHODH 💬 D00749 💬 Leflunomide [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
53 Metabolic pathways 💬
 [1] DHODH 💬 D10172 💬 Teriflunomide [3] 13, 25, 26 💬
54 Metabolic pathways 💬
 [3] DNMT1, DNMT3A, DNMT3B 💬 D03665 💬 Decitabine [3] 13, 60, 63 💬
55 Metabolic pathways 💬
 [1] ENPP2 💬 D11844 💬 Ziritaxestat [2] 51, 85 💬
56 Metabolic pathways 💬
 [1] FDPS 💬 D00939 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
57 Metabolic pathways 💬
 [1] FDPS 💬 D07119 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
58 Metabolic pathways 💬
 [1] FDPS 💬 D08056 💬 Ibandronate [3] 46, 49, 274 💬
59 Metabolic pathways 💬
 [1] FDPS 💬 D00941 💬 Pamidronic acid [3] 270, 271, 274 💬
60 Metabolic pathways 💬
 [1] FDPS 💬 D07281 💬 Pamidronic acid [3] 270, 271, 274 💬
61 Metabolic pathways 💬
 [1] FDPS 💬 D00942 💬 Risedronic acid [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
62 Metabolic pathways 💬
 [1] FDPS 💬 D03234 💬 Risedronic acid [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
63 Metabolic pathways 💬
 [1] FDPS 💬 D08484 💬 Risedronic acid [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
64 Metabolic pathways 💬
 [1] FDPS 💬 D01968 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
65 Metabolic pathways 💬
 [1] FDPS 💬 D06378 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
66 Metabolic pathways 💬
 [1] FDPS 💬 D06379 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
67 Metabolic pathways 💬
 [1] FDPS 💬 D08689 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
68 Metabolic pathways 💬
 [1] GAA 💬 D03207 💬 Alglucosidase alfa [1] 256 💬
69 Metabolic pathways 💬
 [1] GAA 💬 D11744 💬 Avalglucosidase alfa [1] 256 💬
70 Metabolic pathways 💬
 [1] GAA 💬 D11798 💬 Cipaglucosidase alfa [1] 256 💬
71 Metabolic pathways 💬
 [1] GAA 💬 D09605 💬 Duvoglustat [1] 256 💬
72 Metabolic pathways 💬
 [1] GALNS 💬 D10333 💬 Elosulfase alfa [1] 19 💬
73 Metabolic pathways 💬
 [1] GBA 💬 D02810 💬 Alglucerase [1] 19 💬
74 Metabolic pathways 💬
 [1] GBA 💬 D03020 💬 Imiglucerase [1] 19 💬
75 Metabolic pathways 💬
 [1] GBA 💬 D09675 💬 Taliglucerase alfa [1] 19 💬
76 Metabolic pathways 💬
 [1] GBA 💬 D09029 💬 Velaglucerase alfa [1] 19 💬
77 Metabolic pathways 💬
 [1] GLA 💬 D02784 💬 Agalsidase alfa [1] 19 💬
78 Metabolic pathways 💬
 [1] GLA 💬 D03228 💬 Agalsidase beta [1] 19 💬
79 Metabolic pathways 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite [1] 58 💬
80 Metabolic pathways 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
81 Metabolic pathways 💬
 [1] GUCY2C 💬 D09355 💬 Linaclotide [2]  6 , 97 💬
82 Metabolic pathways 💬
 [1] GUSB 💬 D11004 💬 Vestronidase alfa [1] 19 💬
83 Metabolic pathways 💬
 [1] HAO1 💬 D11925 💬 Lumasiran [1] 234 💬
84 Metabolic pathways 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
85 Metabolic pathways 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
86 Metabolic pathways 💬
 [1] HMGCR 💬 D00892 💬 Fluvastatin [3] 79, 218, 222 💬
87 Metabolic pathways 💬
 [1] HMGCR 💬 D07983 💬 Fluvastatin [3] 79, 218, 222 💬
88 Metabolic pathways 💬
 [1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
89 Metabolic pathways 💬
 [1] HMGCR 💬 D00893 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
90 Metabolic pathways 💬
 [1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
91 Metabolic pathways 💬
 [1] HMGCR 💬 D01915 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
92 Metabolic pathways 💬
 [1] HMGCR 💬 D08492 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
93 Metabolic pathways 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
94 Metabolic pathways 💬
 [2] HMOX1, HMOX2 💬 D05922 💬 Stannsoporfin [1] 254 💬
95 Metabolic pathways 💬
 [1] HPD 💬 D05177 💬 Nitisinone [3]  6 , 164, 241 💬
96 Metabolic pathways 💬
 [1] HPRT1 💬 D00161 💬 Mercaptopurine [4] 65, 96, 97, 164 💬
97 Metabolic pathways 💬
 [1] HPRT1 💬 D04931 💬 Mercaptopurine [4] 65, 96, 97, 164 💬
98 Metabolic pathways 💬
 [1] HPRT1 💬 D06109 💬 Tioguanine [2] 13, 37 💬
99 Metabolic pathways 💬
 [1] HPRT1 💬 D08603 💬 Tioguanine [2] 13, 37 💬
100 Metabolic pathways 💬
 [1] IDS 💬 D04499 💬 Idursulfase [1] 19 💬
101 Metabolic pathways 💬
 [1] IDS 💬 D11025 💬 Idursulfase beta [1] 19 💬
102 Metabolic pathways 💬
 [1] IDS 💬 D11812 💬 Pabinafusp alfa [1] 19 💬
103 Metabolic pathways 💬
 [1] IDUA 💬 D04670 💬 Laronidase [2] 19, 256 💬
104 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D01392 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
105 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
106 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
107 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
108 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [36]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
109 Metabolic pathways 💬
 [1] MAOA 💬 D02561 💬 Moclobemide [1]  6  💬
110 Metabolic pathways 💬
 [2] MAOA, MAOB 💬 D02579 💬 Iproniazid [1]  6  💬
111 Metabolic pathways 💬
 [2] MAOA, MAOB 💬 D00505 💬 Phenelzine [1]  6  💬
112 Metabolic pathways 💬
 [2] MAOA, MAOB 💬 D08349 💬 Phenelzine [1]  6  💬
113 Metabolic pathways 💬
 [2] MAOA, MAOB 💬 D05458 💬 Phentermine [1] 97 💬
114 Metabolic pathways 💬
 [2] MAOA, MAOB 💬 D05459 💬 Phentermine [1] 97 💬
115 Metabolic pathways 💬
 [1] MAOB 💬 D02562 💬 Rasagiline [7]  2 ,  5 ,  6 , 13, 17, 58, 66 💬
116 Metabolic pathways 💬
 [1] MAOB 💬 D08469 💬 Rasagiline [7]  2 ,  5 ,  6 , 13, 17, 58, 66 💬
117 Metabolic pathways 💬
 [1] MAOB 💬 D10829 💬 Rasagiline [7]  2 ,  5 ,  6 , 13, 17, 58, 66 💬
118 Metabolic pathways 💬
 [1] MAOB 💬 D10158 💬 Safinamide [2]  6 , 17 💬
119 Metabolic pathways 💬
 [1] MAOB 💬 D00785 💬 Selegiline [1]  6  💬
120 Metabolic pathways 💬
 [1] MAOB 💬 D03731 💬 Selegiline [1]  6  💬
121 Metabolic pathways 💬
 [1] NPR1 💬 D05147 💬 Nesiritide [2] 46, 58 💬
122 Metabolic pathways 💬
 [2] NPR1, NPR2 💬 D04051 💬 Erythrityl tetranitrate [1] 46 💬
123 Metabolic pathways 💬
 [1] NPR2 💬 D11190 💬 Vosoritide [1] 276 💬
124 Metabolic pathways 💬
 [2] NQO1, VKORC1 💬 D00564 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
125 Metabolic pathways 💬
 [2] NQO1, VKORC1 💬 D01280 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
126 Metabolic pathways 💬
 [2] NQO1, VKORC1 💬 D08682 💬 Warfarin [13]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
127 Metabolic pathways 💬
 [1] ODC1 💬 D07883 💬 Eflornithine [1] 65 💬
128 Metabolic pathways 💬
 [1] PAH 💬 D11077 💬 Pegvaliase [1] 240 💬
129 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D00227 💬 Aminophylline [1] 63 💬
130 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D05429 💬 Aminophylline [1] 63 💬
131 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D07546 💬 Bucladesine [1] 246 💬
132 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D00718 💬 Flavoxate [1] 226 💬
133 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D07961 💬 Flavoxate [1] 226 💬
134 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D00371 💬 Theophylline [2] 236, 299 💬
135 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D01712 💬 Theophylline [2] 236, 299 💬
136 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D02017 💬 Theophylline [2] 236, 299 💬
137 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D06103 💬 Theophylline [2] 236, 299 💬
138 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D06104 💬 Theophylline [2] 236, 299 💬
139 Metabolic pathways 💬
 [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
140 Metabolic pathways 💬
 [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
141 Metabolic pathways 💬
 [2] PDE3A, PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
142 Metabolic pathways 💬
 [2] PDE3A, PDE3B 💬 D04720 💬 Levosimendan [1]  2  💬
143 Metabolic pathways 💬
 [2] PDE3A, PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
144 Metabolic pathways 💬
 [2] PDE3A, PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
145 Metabolic pathways 💬
 [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01385 💬 Ibudilast [2]  2 , 13 💬
146 Metabolic pathways 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D08860 💬 Apremilast [7] 46, 50, 56, 97, 107, 162, 271 💬
147 Metabolic pathways 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast [2] 84, 299 💬
148 Metabolic pathways 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram [2]  8 , 13 💬
149 Metabolic pathways 💬
 [2] PDE4A, PDE5A 💬 D00302 💬 Dipyridamole [6] 46, 49, 51, 66, 96, 224 💬
150 Metabolic pathways 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
151 Metabolic pathways 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
152 Metabolic pathways 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
153 Metabolic pathways 💬
 [1] PDE5A 💬 D10027 💬 Udenafil [2] 86, 210 💬
154 Metabolic pathways 💬
 [1] PDE5A 💬 D02731 💬 Vardenafil [3] 13, 86, 299 💬
155 Metabolic pathways 💬
 [1] PDE5A 💬 D03260 💬 Vardenafil [3] 13, 86, 299 💬
156 Metabolic pathways 💬
 [1] PDE5A 💬 D08668 💬 Vardenafil [3] 13, 86, 299 💬
157 Metabolic pathways 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
158 Metabolic pathways 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
159 Metabolic pathways 💬
 [3] PTGES, PTGS1, PTGS2 💬 D01545 💬 Aceclofenac [1] 46 💬
160 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
161 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬
162 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00903 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
163 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00904 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
164 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D07816 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
165 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00330 💬 Flurbiprofen [3] 13, 21, 46 💬
166 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D01475 💬 Flurbiprofen [3] 13, 21, 46 💬
167 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D02290 💬 Flurbiprofen [3] 13, 21, 46 💬
168 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00126 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
169 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D01122 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
170 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D04490 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
171 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D06606 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
172 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
173 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D01565 💬 Indomethacin [3] 225, 271, 298 💬
174 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D02110 💬 Indomethacin [3] 225, 271, 298 💬
175 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00132 💬 Ketoprofen [1] 46 💬
176 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00813 💬 Ketorolac [2] 70, 226 💬
177 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
178 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D08149 💬 Loxoprofen [2] 46, 271 💬
179 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00118 💬 Naproxen [4] 13, 46, 107, 271 💬
180 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00428 💬 Salsalate [1]  5  💬
181 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00120 💬 Sulindac [1] 206 💬
182 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D01183 💬 Tolfenamic acid [1]  5  💬
183 Metabolic pathways 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
184 Metabolic pathways 💬
 [1] PTGS2 💬 D00130 💬 Diflunisal [1] 28 💬
185 Metabolic pathways 💬
 [1] PTGS2 💬 D00315 💬 Etodolac [1] 46 💬
186 Metabolic pathways 💬
 [1] PTGS2 💬 D03710 💬 Etoricoxib [2] 46, 271 💬
187 Metabolic pathways 💬
 [1] PTGS2 💬 D03714 💬 Lumiracoxib [1] 46 💬
188 Metabolic pathways 💬
 [1] PTGS2 💬 D00969 💬 Meloxicam [4] 46, 49, 271, 296 💬
189 Metabolic pathways 💬
 [1] PTGS2 💬 D01049 💬 Nimesulide [1] 46 💬
190 Metabolic pathways 💬
 [1] PTGS2 💬 D03716 💬 Parecoxib [2] 46, 271 💬
191 Metabolic pathways 💬
 [1] PTGS2 💬 D00568 💬 Rofecoxib [1] 46 💬
192 Metabolic pathways 💬
 [1] PTGS2 💬 D02709 💬 Valdecoxib [1] 46 💬
193 Metabolic pathways 💬
 [1] RRM1 💬 D01370 💬 Cladribine [3] 11, 13, 94 💬
194 Metabolic pathways 💬
 [1] RRM1 💬 D03546 💬 Clofarabine [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
195 Metabolic pathways 💬
 [1] RRM1 💬 D01907 💬 Fludarabine [19] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
196 Metabolic pathways 💬
 [1] RRM1 💬 D07966 💬 Fludarabine [19] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
197 Metabolic pathways 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
198 Metabolic pathways 💬
 [1] SMPD1 💬 D10820 💬 Olipudase alfa [1] 19 💬
199 Metabolic pathways 💬
 [2] SRD5A1, SRD5A2 💬 D03820 💬 Dutasteride [2]  1 ,  2  💬
200 Metabolic pathways 💬
 [1] SRD5A2 💬 D00321 💬 Finasteride [1]  6  💬
201 Metabolic pathways 💬
 [2] TPH1, TPH2 💬 D09973 💬 Telotristat [1] 97 💬
202 Metabolic pathways 💬
 [1] TPO 💬 D00401 💬 Methimazole [1] 50 💬
203 Metabolic pathways 💬
 [1] TYMS 💬 D01223 💬 Capecitabine [1] 94 💬
204 Metabolic pathways 💬
 [1] TYMS 💬 D01244 💬 Tegafur [1] 46 💬
205 Metabolic pathways 💬
 [1] UGCG 💬 D09893 💬 Eliglustat [1] 19 💬
206 Metabolic pathways 💬
 [1] UGCG 💬 D11439 💬 Lucerastat [1] 19 💬
207 Metabolic pathways 💬
 [1] UGCG 💬 D05032 💬 Miglustat [3] 19, 256, 299 💬
208 Metabolic pathways 💬
 [1] UGCG 💬 D11633 💬 Venglustat [3]  6 , 19, 67 💬
209 Metabolic pathways 💬
 [1] VKORC1 💬 D08354 💬 Phenindione [1] 65 💬
210 Metabolic pathways 💬
 [1] XDH 💬 D00224 💬 Allopurinol [6]  6 , 46, 57, 66, 96, 97 💬
211 Metabolic pathways 💬
 [1] XDH 💬 D01206 💬 Febuxostat [3]  2 ,  6 , 13 💬