Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 FoxO signaling pathway 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
2 FoxO signaling pathway 💬
 [2] BRAF, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
3 FoxO signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
4 FoxO signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
5 FoxO signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
6 FoxO signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
7 FoxO signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
8 FoxO signaling pathway 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
9 FoxO signaling pathway 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
10 FoxO signaling pathway 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
11 FoxO signaling pathway 💬
 [1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
12 FoxO signaling pathway 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
13 FoxO signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
14 FoxO signaling pathway 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
15 FoxO signaling pathway 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
16 FoxO signaling pathway 💬
 [2] IL10, IL6 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
17 FoxO signaling pathway 💬
 [1] IL6 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
18 FoxO signaling pathway 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
19 FoxO signaling pathway 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
20 FoxO signaling pathway 💬
 [1] INSR 💬 D04539 💬 Insulin detemir [1] 299 💬
21 FoxO signaling pathway 💬
 [1] INSR 💬 D03250 💬 Insulin glargine [1] 299 💬
22 FoxO signaling pathway 💬
 [1] INSR 💬 D00085 💬 Insulin human [2] 96, 156 💬
23 FoxO signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
24 FoxO signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
25 FoxO signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
26 FoxO signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
27 FoxO signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
28 FoxO signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
29 FoxO signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
30 FoxO signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
31 FoxO signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
32 FoxO signaling pathway 💬
 [1] PLK1 💬 D10154 💬 Rigosertib [1] 36 💬
33 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
34 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
35 FoxO signaling pathway 💬
 [1] S1PR1 💬 D11283 💬 Cenerimod [1] 49 💬
36 FoxO signaling pathway 💬
 [1] S1PR1 💬 D10001 💬 Fingolimod [3] 13, 14, 156 💬
37 FoxO signaling pathway 💬
 [1] S1PR1 💬 D11215 💬 Ponesimod [1] 13 💬
38 FoxO signaling pathway 💬
 [1] S1PR1 💬 D11460 💬 Siponimod [2] 13, 50 💬
39 FoxO signaling pathway 💬
 [2] S1PR1, S1PR4 💬 D10930 💬 Etrasimod [3] 96, 97, 98 💬
40 FoxO signaling pathway 💬
 [2] S1PR1, S1PR4 💬 D10968 💬 Ozanimod [3] 13, 96, 97 💬
41 FoxO signaling pathway 💬
 [3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [4] 51, 85, 222, 274 💬