Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Cytosolic DNA-sensing pathway 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬	D09662 💬	Rontalizumab	[1] 49 💬
2	Cytosolic DNA-sensing pathway 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬	D09668 💬	Sifalimumab	[1] 49 💬
3	Cytosolic DNA-sensing pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
4	Cytosolic DNA-sensing pathway 💬	[1] IL1B 💬	D09911 💬	Gevokizumab	[4] 41, 50, 56, 269 💬
5	Cytosolic DNA-sensing pathway 💬	[1] IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
6	Cytosolic DNA-sensing pathway 💬	[2] IL1B, IL6 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
7	Cytosolic DNA-sensing pathway 💬	[1] IL6 💬	D08976 💬	Pomalidomide	[6] 28, 34, 51, 85, 227, 331 💬
8	Cytosolic DNA-sensing pathway 💬	[1] IL6 💬	D09669 💬	Siltuximab	[2] 28, 331 💬
9	Cytosolic DNA-sensing pathway 💬	[1] IL6 💬	D10080 💬	Sirukumab	[2] 41, 46 💬
10	Cytosolic DNA-sensing pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[4] 46, 51, 53, 271 💬
11	Cytosolic DNA-sensing pathway 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬