Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	C-type lectin receptor signaling pathway 💬	[4] IL10, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
2	C-type lectin receptor signaling pathway 💬	[3] IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	[17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
3	C-type lectin receptor signaling pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
4	C-type lectin receptor signaling pathway 💬	[1] IL1B 💬	D09911 💬	Gevokizumab	[4] 41, 50, 56, 269 💬
5	C-type lectin receptor signaling pathway 💬	[1] IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
6	C-type lectin receptor signaling pathway 💬	[1] IL23A 💬	D10912 💬	Brazikumab	[2] 96, 97 💬
7	C-type lectin receptor signaling pathway 💬	[1] IL23A 💬	D10438 💬	Guselkumab	[5] 37, 41, 51, 96, 97 💬
8	C-type lectin receptor signaling pathway 💬	[1] IL23A 💬	D11123 💬	Mirikizumab	[3] 37, 96, 97 💬
9	C-type lectin receptor signaling pathway 💬	[1] IL23A 💬	D11052 💬	Risankizumab	[4] 37, 96, 97, 271 💬
10	C-type lectin receptor signaling pathway 💬	[1] IL23A 💬	D10400 💬	Tildrakizumab	[2] 162, 271 💬

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