Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00615 💬 Amlodipine [4] 13, 51, 67, 298 💬
2 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02914 💬 Amlodipine [4] 13, 51, 67, 298 💬
3 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07450 💬 Amlodipine [4] 13, 51, 67, 298 💬
4 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01173 💬 Cilnidipine [1] 67 💬
5 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00616 💬 Diltiazem [3] 51, 58, 86 💬
6 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D03830 💬 Diltiazem [3] 51, 58, 86 💬
7 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
8 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00349 💬 Isradipine [1]  6  💬
9 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00617 💬 Nicardipine [2] 70, 86 💬
10 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
11 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00437 💬 Nifedipine [2] 50, 81 💬
12 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01908 💬 Nilvadipine [1] 90 💬
13 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D05442 💬 Perhexiline [2] 58, 272 💬
14 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08340 💬 Perhexiline [2] 58, 272 💬
15 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
16 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
17 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00619 💬 Verapamil [3] 96, 140, 167 💬
18 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02356 💬 Verapamil [3] 96, 140, 167 💬
19 GnRH secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D01303 💬 Flunarizine [4] 58, 86, 149, 215 💬
20 GnRH secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine [4] 58, 86, 149, 215 💬
21 GnRH secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
22 GnRH secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00538 💬 Zonisamide [1]  6  💬
23 GnRH secretion 💬
 [1] ESR2 💬 D00962 💬 Clomifene [1] 74 💬
24 GnRH secretion 💬
 [1] ESR2 💬 D07726 💬 Clomifene [1] 74 💬
25 GnRH secretion 💬
 [1] ESR2 💬 D11513 💬 Estetrol [1] 53 💬
26 GnRH secretion 💬
 [1] ESR2 💬 D11514 💬 Estetrol [1] 53 💬
27 GnRH secretion 💬
 [1] ESR2 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
28 GnRH secretion 💬
 [1] ESR2 💬 D01413 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
29 GnRH secretion 💬
 [1] ESR2 💬 D01617 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
30 GnRH secretion 💬
 [1] ESR2 💬 D01953 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
31 GnRH secretion 💬
 [1] ESR2 💬 D04061 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
32 GnRH secretion 💬
 [1] ESR2 💬 D04063 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
33 GnRH secretion 💬
 [1] ESR2 💬 D04064 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
34 GnRH secretion 💬
 [1] ESR2 💬 D04065 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
35 GnRH secretion 💬
 [1] ESR2 💬 D01413 💬 Estradiol valerate [1] 65 💬
36 GnRH secretion 💬
 [1] ESR2 💬 D00185 💬 Estriol [2] 13, 227 💬
37 GnRH secretion 💬
 [1] ESR2 💬 D01986 💬 Estriol [2] 13, 227 💬
38 GnRH secretion 💬
 [1] ESR2 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
39 GnRH secretion 💬
 [1] ESR2 💬 D00575 💬 Mestranol [2] 46, 49 💬
40 GnRH secretion 💬
 [1] ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
41 GnRH secretion 💬
 [1] ESR2 💬 D02217 💬 Raloxifene [1] 46 💬
42 GnRH secretion 💬
 [1] ESR2 💬 D08465 💬 Raloxifene [1] 46 💬
43 GnRH secretion 💬
 [1] ESR2 💬 D00966 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
44 GnRH secretion 💬
 [1] ESR2 💬 D08559 💬 Tamoxifen [4]  2 , 86, 113, 227 💬
45 GnRH secretion 💬
 [2] GABBR1, GABBR2 💬 D09791 💬 Arbaclofen [2] 13, 206 💬
46 GnRH secretion 💬
 [2] GABBR1, GABBR2 💬 D08861 💬 Arbaclofen Placarbil [1] 13 💬
47 GnRH secretion 💬
 [2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [7]  2 , 10, 13, 18, 65, 149, 206 💬
48 GnRH secretion 💬
 [1] KCNJ11 💬 D00294 💬 Diazoxide [2] 13, 193 💬
49 GnRH secretion 💬
 [1] KCNJ11 💬 D00418 💬 Minoxidil [1] 179 💬
50 GnRH secretion 💬
 [1] KCNJ11 💬 D00594 💬 Repaglinide [3]  6 , 21, 299 💬
51 GnRH secretion 💬
 [3] KCNJ11, KCNJ3, KCNJ5 💬 D00636 💬 Amiodarone [2] 28, 127 💬
52 GnRH secretion 💬
 [3] KCNJ11, KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
53 GnRH secretion 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
54 GnRH secretion 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
55 GnRH secretion 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
56 GnRH secretion 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
57 GnRH secretion 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
58 GnRH secretion 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
59 GnRH secretion 💬
 [1] RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
60 GnRH secretion 💬
 [1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬