Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Parkinson disease 💬	[1] ADORA2A 💬	D00045 💬	Adenosine	[3] 13, 58, 65 💬
2	Parkinson disease 💬	[1] ADORA2A 💬	D02769 💬	Adenosine phosphate	[1] 46 💬
3	Parkinson disease 💬	[1] ADORA2A 💬	D00528 💬	Caffeine	[9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬
4	Parkinson disease 💬	[1] ADORA2A 💬	D01453 💬	Caffeine	[9] 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬
5	Parkinson disease 💬	[1] ADORA2A 💬	D04641 💬	Istradefylline	[1] 6 💬
6	Parkinson disease 💬	[1] ADORA2A 💬	D09717 💬	Preladenant	[1] 6 💬
7	Parkinson disease 💬	[1] ADORA2A 💬	D05711 💬	Regadenoson	[1] 58 💬
8	Parkinson disease 💬	[1] ADORA2A 💬	D02017 💬	Theophylline	[2] 236, 299 💬
9	Parkinson disease 💬	[1] ADORA2A 💬	D10174 💬	Tozadenant	[1] 6 💬
10	Parkinson disease 💬	[1] CASP9 💬	D11195 💬	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬
11	Parkinson disease 💬	[1] DRD1 💬	D11431 💬	Tavapadon	[1] 6 💬
12	Parkinson disease 💬	[2] DRD1, DRD2 💬	D02004 💬	Apomorphine	[3] 5 , 6 , 7 💬
13	Parkinson disease 💬	[2] DRD1, DRD2 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
14	Parkinson disease 💬	[2] DRD1, DRD2 💬	D09886 💬	Dexpramipexole	[1] 2 💬
15	Parkinson disease 💬	[2] DRD1, DRD2 💬	D00633 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
16	Parkinson disease 💬	[2] DRD1, DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
17	Parkinson disease 💬	[2] DRD1, DRD2 💬	D01044 💬	Flupentixol	[1] 97 💬
18	Parkinson disease 💬	[2] DRD1, DRD2 💬	D11839 💬	Foslevodopa	[1] 6 💬
19	Parkinson disease 💬	[2] DRD1, DRD2 💬	D00059 💬	Levodopa	[8] 2 , 4 , 6 , 17, 90, 140, 164, 201 💬
20	Parkinson disease 💬	[2] DRD1, DRD2 💬	D00502 💬	Pergolide	[1] 6 💬
21	Parkinson disease 💬	[2] DRD1, DRD2 💬	D08339 💬	Pergolide	[1] 6 💬
22	Parkinson disease 💬	[1] DRD2 💬	D01164 💬	Aripiprazole	[2] 6 , 206 💬
23	Parkinson disease 💬	[1] DRD2 💬	D00780 💬	Bromocriptine	[2] 6 , 74 💬
24	Parkinson disease 💬	[1] DRD2 💬	D03165 💬	Bromocriptine	[2] 6 , 74 💬
25	Parkinson disease 💬	[1] DRD2 💬	D00702 💬	Buspirone	[3] 6 , 51, 179 💬
26	Parkinson disease 💬	[1] DRD2 💬	D07593 💬	Buspirone	[3] 6 , 51, 179 💬
27	Parkinson disease 💬	[1] DRD2 💬	D00987 💬	Cabergoline	[3] 6 , 74, 75 💬
28	Parkinson disease 💬	[1] DRD2 💬	D09997 💬	Cariprazine	[1] 21 💬
29	Parkinson disease 💬	[1] DRD2 💬	D00270 💬	Chlorpromazine	[1] 254 💬
30	Parkinson disease 💬	[1] DRD2 💬	D00789 💬	Chlorpromazine	[1] 254 💬
31	Parkinson disease 💬	[1] DRD2 💬	D03274 💬	Chlorpromazine	[1] 254 💬
32	Parkinson disease 💬	[1] DRD2 💬	D04034 💬	Chlorpromazine	[1] 254 💬
33	Parkinson disease 💬	[1] DRD2 💬	D01745 💬	Domperidone	[5] 6 , 13, 17, 51, 230 💬
34	Parkinson disease 💬	[1] DRD2 💬	D07868 💬	Domperidone	[5] 6 , 13, 17, 51, 230 💬
35	Parkinson disease 💬	[1] DRD2 💬	D00136 💬	Haloperidol	[1] 8 💬
36	Parkinson disease 💬	[1] DRD2 💬	D01898 💬	Haloperidol	[1] 8 💬
37	Parkinson disease 💬	[1] DRD2 💬	D01462 💬	Lisuride	[2] 6 , 86 💬
38	Parkinson disease 💬	[1] DRD2 💬	D08132 💬	Lisuride	[2] 6 , 86 💬
39	Parkinson disease 💬	[1] DRD2 💬	D07309 💬	Melperone	[1] 6 💬
40	Parkinson disease 💬	[1] DRD2 💬	D00726 💬	Metoclopramide	[1] 51 💬
41	Parkinson disease 💬	[1] DRD2 💬	D02213 💬	Metoclopramide	[1] 51 💬
42	Parkinson disease 💬	[1] DRD2 💬	D05008 💬	Metoclopramide	[1] 51 💬
43	Parkinson disease 💬	[1] DRD2 💬	D00454 💬	Olanzapine	[2] 2 , 8 💬
44	Parkinson disease 💬	[1] DRD2 💬	D06623 💬	Olanzapine	[2] 2 , 8 💬
45	Parkinson disease 💬	[1] DRD2 💬	D09397 💬	Pardoprunox	[1] 6 💬
46	Parkinson disease 💬	[1] DRD2 💬	D00560 💬	Pimozide	[1] 2 💬
47	Parkinson disease 💬	[1] DRD2 💬	D07305 💬	Piribedil	[1] 6 💬
48	Parkinson disease 💬	[1] DRD2 💬	D00559 💬	Pramipexole	[3] 2 , 6 , 20 💬
49	Parkinson disease 💬	[1] DRD2 💬	D05575 💬	Pramipexole	[3] 2 , 6 , 20 💬
50	Parkinson disease 💬	[1] DRD2 💬	D09953 💬	Pridopidine	[3] 2 , 6 , 8 💬
51	Parkinson disease 💬	[1] DRD2 💬	D00458 💬	Quetiapine	[2] 6 , 13 💬
52	Parkinson disease 💬	[1] DRD2 💬	D08456 💬	Quetiapine	[2] 6 , 13 💬
53	Parkinson disease 💬	[1] DRD2 💬	D00426 💬	Risperidone	[5] 8 , 156, 179, 187, 206 💬
54	Parkinson disease 💬	[1] DRD2 💬	D00784 💬	Ropinirole	[4] 2 , 6 , 74, 309 💬
55	Parkinson disease 💬	[1] DRD2 💬	D08489 💬	Ropinirole	[4] 2 , 6 , 74, 309 💬
56	Parkinson disease 💬	[1] DRD2 💬	D05768 💬	Rotigotine	[2] 6 , 127 💬
57	Parkinson disease 💬	[1] DRD2 💬	D01226 💬	Sulpiride	[5] 2 , 6 , 17, 46, 70 💬
58	Parkinson disease 💬	[1] DRD2 💬	D08549 💬	Sulpiride	[5] 2 , 6 , 17, 46, 70 💬
59	Parkinson disease 💬	[1] DRD2 💬	D01348 💬	Terguride	[2] 51, 86 💬
60	Parkinson disease 💬	[1] DRD2 💬	D08590 💬	Tiapride	[1] 8 💬
61	Parkinson disease 💬	[1] DRD2 💬	D00799 💬	Trifluoperazine	[2] 283, 284 💬
62	Parkinson disease 💬	[1] DRD2 💬	D01448 💬	Trifluoperazine	[2] 283, 284 💬
63	Parkinson disease 💬	[1] DRD2 💬	D08636 💬	Trifluoperazine	[2] 283, 284 💬
64	Parkinson disease 💬	[1] KEAP1 💬	D03846 💬	Dimethyl fumarate	[5] 13, 49, 51, 86, 296 💬
65	Parkinson disease 💬	[1] MAOA 💬	D02561 💬	Moclobemide	[1] 6 💬
66	Parkinson disease 💬	[2] MAOA, MAOB 💬	D02579 💬	Iproniazid	[1] 6 💬
67	Parkinson disease 💬	[2] MAOA, MAOB 💬	D00505 💬	Phenelzine	[1] 6 💬
68	Parkinson disease 💬	[2] MAOA, MAOB 💬	D08349 💬	Phenelzine	[1] 6 💬
69	Parkinson disease 💬	[3] MAOA, MAOB, SLC6A3 💬	D05458 💬	Phentermine	[1] 97 💬
70	Parkinson disease 💬	[3] MAOA, MAOB, SLC6A3 💬	D05459 💬	Phentermine	[1] 97 💬
71	Parkinson disease 💬	[1] MAOB 💬	D02562 💬	Rasagiline	[7] 2 , 5 , 6 , 13, 17, 58, 66 💬
72	Parkinson disease 💬	[1] MAOB 💬	D08469 💬	Rasagiline	[7] 2 , 5 , 6 , 13, 17, 58, 66 💬
73	Parkinson disease 💬	[1] MAOB 💬	D10829 💬	Rasagiline	[7] 2 , 5 , 6 , 13, 17, 58, 66 💬
74	Parkinson disease 💬	[1] MAOB 💬	D10158 💬	Safinamide	[2] 6 , 17 💬
75	Parkinson disease 💬	[1] MAOB 💬	D00785 💬	Selegiline	[1] 6 💬
76	Parkinson disease 💬	[1] MAOB 💬	D03731 💬	Selegiline	[1] 6 💬
77	Parkinson disease 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
78	Parkinson disease 💬	[1] MAPT 💬	D11210 💬	Flortaucipir	[3] 5 , 7 , 127 💬
79	Parkinson disease 💬	[1] MAPT 💬	D11293 💬	Gosuranemab	[1] 5 💬
80	Parkinson disease 💬	[1] NFE2L2 💬	D10964 💬	Omaveloxolone	[1] 18 💬
81	Parkinson disease 💬	[1] PSMB5 💬	D03150 💬	Bortezomib	[16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬
82	Parkinson disease 💬	[1] PSMB5 💬	D08880 💬	Carfilzomib	[1] 28 💬
83	Parkinson disease 💬	[1] PSMB5 💬	D10130 💬	Ixazomib	[5] 13, 16, 28, 51, 61 💬
84	Parkinson disease 💬	[1] SLC18A2 💬	D10701 💬	Deutetrabenazine	[1] 8 💬
85	Parkinson disease 💬	[1] SLC18A2 💬	D08575 💬	Tetrabenazine	[1] 8 💬
86	Parkinson disease 💬	[1] SLC18A2 💬	D10675 💬	Valbenazine	[1] 8 💬
87	Parkinson disease 💬	[1] SLC6A3 💬	D03215 💬	Armodafinil	[3] 6 , 13, 84 💬
88	Parkinson disease 💬	[1] SLC6A3 💬	D00817 💬	Bupropion	[5] 8 , 18, 21, 96, 171 💬
89	Parkinson disease 💬	[1] SLC6A3 💬	D07591 💬	Bupropion	[5] 8 , 18, 21, 96, 171 💬
90	Parkinson disease 💬	[1] SLC6A3 💬	D07938 💬	Bupropion	[5] 8 , 18, 21, 96, 171 💬
91	Parkinson disease 💬	[1] SLC6A3 💬	D08130 💬	Lisdexamfetamine	[1] 13 💬
92	Parkinson disease 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
93	Parkinson disease 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
94	Parkinson disease 💬	[1] SNCA 💬	D11420 💬	Prasinezumab	[1] 6 💬
95	Parkinson disease 💬	[1] SOD1 💬	D11811 💬	Tofersen	[1] 2 💬
96	Parkinson disease 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D11595 💬	Belantamab mafodotin	[1] 28 💬
97	Parkinson disease 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D09587 💬	Brentuximab vedotin	[2] 49, 51 💬
98	Parkinson disease 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00570 💬	Colchicine	[7] 2 , 42, 46, 56, 93, 210, 266 💬
99	Parkinson disease 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D00491 💬	Paclitaxel	[2] 46, 85 💬
100	Parkinson disease 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D05333 💬	Paclitaxel	[2] 46, 85 💬
101	Parkinson disease 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D01068 💬	Vinblastine	[2] 34, 65 💬
102	Parkinson disease 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D08675 💬	Vinblastine	[2] 34, 65 💬
103	Parkinson disease 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D02197 💬	Vincristine	[4] 26, 34, 65, 331 💬
104	Parkinson disease 💬	[9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	D08679 💬	Vincristine	[4] 26, 34, 65, 331 💬