Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Cocaine addiction 💬
 [1] DDC 💬 D03082 💬 Benserazide [1]  6  💬
2 Cocaine addiction 💬
 [1] DDC 💬 D00558 💬 Carbidopa [9]  2 ,  4 ,  6 , 13, 17, 90, 140, 164, 201 💬
3 Cocaine addiction 💬
 [1] DRD1 💬 D11431 💬 Tavapadon [1]  6  💬
4 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
5 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
6 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D09886 💬 Dexpramipexole [1]  2  💬
7 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
8 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
9 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D01044 💬 Flupentixol [1] 97 💬
10 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D11839 💬 Foslevodopa [1]  6  💬
11 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D00059 💬 Levodopa [8]  2 ,  4 ,  6 , 17, 90, 140, 164, 201 💬
12 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D00502 💬 Pergolide [1]  6  💬
13 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 D08339 💬 Pergolide [1]  6  💬
14 Cocaine addiction 💬
 [1] DRD2 💬 D01164 💬 Aripiprazole [2]  6 , 206 💬
15 Cocaine addiction 💬
 [1] DRD2 💬 D00780 💬 Bromocriptine [2]  6 , 74 💬
16 Cocaine addiction 💬
 [1] DRD2 💬 D03165 💬 Bromocriptine [2]  6 , 74 💬
17 Cocaine addiction 💬
 [1] DRD2 💬 D00702 💬 Buspirone [3]  6 , 51, 179 💬
18 Cocaine addiction 💬
 [1] DRD2 💬 D07593 💬 Buspirone [3]  6 , 51, 179 💬
19 Cocaine addiction 💬
 [1] DRD2 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
20 Cocaine addiction 💬
 [1] DRD2 💬 D09997 💬 Cariprazine [1] 21 💬
21 Cocaine addiction 💬
 [1] DRD2 💬 D00270 💬 Chlorpromazine [1] 254 💬
22 Cocaine addiction 💬
 [1] DRD2 💬 D00789 💬 Chlorpromazine [1] 254 💬
23 Cocaine addiction 💬
 [1] DRD2 💬 D03274 💬 Chlorpromazine [1] 254 💬
24 Cocaine addiction 💬
 [1] DRD2 💬 D04034 💬 Chlorpromazine [1] 254 💬
25 Cocaine addiction 💬
 [1] DRD2 💬 D01745 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
26 Cocaine addiction 💬
 [1] DRD2 💬 D07868 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
27 Cocaine addiction 💬
 [1] DRD2 💬 D00136 💬 Haloperidol [1]  8  💬
28 Cocaine addiction 💬
 [1] DRD2 💬 D01898 💬 Haloperidol [1]  8  💬
29 Cocaine addiction 💬
 [1] DRD2 💬 D01462 💬 Lisuride [2]  6 , 86 💬
30 Cocaine addiction 💬
 [1] DRD2 💬 D08132 💬 Lisuride [2]  6 , 86 💬
31 Cocaine addiction 💬
 [1] DRD2 💬 D07309 💬 Melperone [1]  6  💬
32 Cocaine addiction 💬
 [1] DRD2 💬 D00726 💬 Metoclopramide [1] 51 💬
33 Cocaine addiction 💬
 [1] DRD2 💬 D02213 💬 Metoclopramide [1] 51 💬
34 Cocaine addiction 💬
 [1] DRD2 💬 D05008 💬 Metoclopramide [1] 51 💬
35 Cocaine addiction 💬
 [1] DRD2 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
36 Cocaine addiction 💬
 [1] DRD2 💬 D06623 💬 Olanzapine [2]  2 ,  8  💬
37 Cocaine addiction 💬
 [1] DRD2 💬 D09397 💬 Pardoprunox [1]  6  💬
38 Cocaine addiction 💬
 [1] DRD2 💬 D00560 💬 Pimozide [1]  2  💬
39 Cocaine addiction 💬
 [1] DRD2 💬 D07305 💬 Piribedil [1]  6  💬
40 Cocaine addiction 💬
 [1] DRD2 💬 D00559 💬 Pramipexole [3]  2 ,  6 , 20 💬
41 Cocaine addiction 💬
 [1] DRD2 💬 D05575 💬 Pramipexole [3]  2 ,  6 , 20 💬
42 Cocaine addiction 💬
 [1] DRD2 💬 D09953 💬 Pridopidine [3]  2 ,  6 ,  8  💬
43 Cocaine addiction 💬
 [1] DRD2 💬 D00458 💬 Quetiapine [2]  6 , 13 💬
44 Cocaine addiction 💬
 [1] DRD2 💬 D08456 💬 Quetiapine [2]  6 , 13 💬
45 Cocaine addiction 💬
 [1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
46 Cocaine addiction 💬
 [1] DRD2 💬 D00784 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬
47 Cocaine addiction 💬
 [1] DRD2 💬 D08489 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬
48 Cocaine addiction 💬
 [1] DRD2 💬 D05768 💬 Rotigotine [2]  6 , 127 💬
49 Cocaine addiction 💬
 [1] DRD2 💬 D01226 💬 Sulpiride [5]  2 ,  6 , 17, 46, 70 💬
50 Cocaine addiction 💬
 [1] DRD2 💬 D08549 💬 Sulpiride [5]  2 ,  6 , 17, 46, 70 💬
51 Cocaine addiction 💬
 [1] DRD2 💬 D01348 💬 Terguride [2] 51, 86 💬
52 Cocaine addiction 💬
 [1] DRD2 💬 D08590 💬 Tiapride [1]  8  💬
53 Cocaine addiction 💬
 [1] DRD2 💬 D00799 💬 Trifluoperazine [2] 283, 284 💬
54 Cocaine addiction 💬
 [1] DRD2 💬 D01448 💬 Trifluoperazine [2] 283, 284 💬
55 Cocaine addiction 💬
 [1] DRD2 💬 D08636 💬 Trifluoperazine [2] 283, 284 💬
56 Cocaine addiction 💬
 [1] GRIA2 💬 D08964 💬 Perampanel [3]  2 ,  6 , 144 💬
57 Cocaine addiction 💬
 [1] GRIA2 💬 D02696 💬 Talampanel [2]  2 ,  6  💬
58 Cocaine addiction 💬
 [1] GRIA2 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
59 Cocaine addiction 💬
 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
60 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D02780 💬 Acamprosate [2]  6 , 206 💬
61 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07058 💬 Acamprosate [2]  6 , 206 💬
62 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00777 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
63 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
64 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
65 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
66 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
67 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine [3]  2 ,  4 , 70 💬
68 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00711 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
69 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
70 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
71 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D04905 💬 Memantine [7]  2 ,  6 ,  8 , 13, 49, 127, 205 💬
72 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [7]  2 ,  6 ,  8 , 13, 49, 127, 205 💬
73 Cocaine addiction 💬
 [1] MAOA 💬 D02561 💬 Moclobemide [1]  6  💬
74 Cocaine addiction 💬
 [2] MAOA, MAOB 💬 D02579 💬 Iproniazid [1]  6  💬
75 Cocaine addiction 💬
 [2] MAOA, MAOB 💬 D00505 💬 Phenelzine [1]  6  💬
76 Cocaine addiction 💬
 [2] MAOA, MAOB 💬 D08349 💬 Phenelzine [1]  6  💬
77 Cocaine addiction 💬
 [3] MAOA, MAOB, SLC6A3 💬 D05458 💬 Phentermine [1] 97 💬
78 Cocaine addiction 💬
 [3] MAOA, MAOB, SLC6A3 💬 D05459 💬 Phentermine [1] 97 💬
79 Cocaine addiction 💬
 [1] MAOB 💬 D02562 💬 Rasagiline [7]  2 ,  5 ,  6 , 13, 17, 58, 66 💬
80 Cocaine addiction 💬
 [1] MAOB 💬 D08469 💬 Rasagiline [7]  2 ,  5 ,  6 , 13, 17, 58, 66 💬
81 Cocaine addiction 💬
 [1] MAOB 💬 D10829 💬 Rasagiline [7]  2 ,  5 ,  6 , 13, 17, 58, 66 💬
82 Cocaine addiction 💬
 [1] MAOB 💬 D10158 💬 Safinamide [2]  6 , 17 💬
83 Cocaine addiction 💬
 [1] MAOB 💬 D00785 💬 Selegiline [1]  6  💬
84 Cocaine addiction 💬
 [1] MAOB 💬 D03731 💬 Selegiline [1]  6  💬
85 Cocaine addiction 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
86 Cocaine addiction 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
87 Cocaine addiction 💬
 [1] SLC18A2 💬 D10701 💬 Deutetrabenazine [1]  8  💬
88 Cocaine addiction 💬
 [1] SLC18A2 💬 D08575 💬 Tetrabenazine [1]  8  💬
89 Cocaine addiction 💬
 [1] SLC18A2 💬 D10675 💬 Valbenazine [1]  8  💬
90 Cocaine addiction 💬
 [1] SLC6A3 💬 D03215 💬 Armodafinil [3]  6 , 13, 84 💬
91 Cocaine addiction 💬
 [1] SLC6A3 💬 D00817 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
92 Cocaine addiction 💬
 [1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
93 Cocaine addiction 💬
 [1] SLC6A3 💬 D07938 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
94 Cocaine addiction 💬
 [1] SLC6A3 💬 D08130 💬 Lisdexamfetamine [1] 13 💬
95 Cocaine addiction 💬
 [1] SLC6A3 💬 D01296 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬
96 Cocaine addiction 💬
 [1] SLC6A3 💬 D04999 💬 Methylphenidate [7]  6 , 13, 34, 84, 113, 179, 206 💬