Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Nicotine addiction 💬
 [1] CACNA1B 💬 D01173 💬 Cilnidipine [1] 67 💬
2 Nicotine addiction 💬
 [4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 D03365 💬 Nicotine [3]  6 , 13, 84 💬
3 Nicotine addiction 💬
 [4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 D05156 💬 Nicotine [3]  6 , 13, 84 💬
4 Nicotine addiction 💬
 [4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 D05157 💬 Nicotine [3]  6 , 13, 84 💬
5 Nicotine addiction 💬
 [4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 D00765 💬 Rocuronium [1] 296 💬
6 Nicotine addiction 💬
 [2] CHRNA4, CHRNB2 💬 D08669 💬 Varenicline [2]  6 , 18 💬
7 Nicotine addiction 💬
 [1] GABRA1 💬 D00548 💬 Etomidate [1]  6  💬
8 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
9 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D11149 💬 Brexanolone [1] 205 💬
10 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00267 💬 Chlordiazepoxide [1] 46 💬
11 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00693 💬 Chlordiazepoxide [1] 46 💬
12 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D01253 💬 Clobazam [2] 140, 144 💬
13 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00280 💬 Clonazepam [1]  6  💬
14 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D07784 💬 Delorazepam [3]  6 , 46, 97 💬
15 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00293 💬 Diazepam [3] 46, 155, 298 💬
16 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D02624 💬 Eszopiclone [3]  6 , 13, 46 💬
17 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D01514 💬 Etizolam [1] 46 💬
18 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00697 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬
19 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D04282 💬 Gaboxadol [2] 201, 206 💬
20 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D04300 💬 Ganaxolone [4] 145, 152, 158, 206 💬
21 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00365 💬 Lorazepam [2] 36, 231 💬
22 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00550 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
23 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00696 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
24 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D05028 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
25 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [10]  6 , 21, 22, 34, 46, 70, 75, 84, 98, 296 💬
26 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00706 💬 Zolpidem [3]  5 ,  6 , 46 💬
27 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D08690 💬 Zolpidem [3]  5 ,  6 , 46 💬
28 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D01372 💬 Zopiclone [1]  6  💬
29 Nicotine addiction 💬
 [20] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
30 Nicotine addiction 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 D08964 💬 Perampanel [3]  2 ,  6 , 144 💬
31 Nicotine addiction 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 D02696 💬 Talampanel [2]  2 ,  6  💬
32 Nicotine addiction 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
33 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D02780 💬 Acamprosate [2]  6 , 206 💬
34 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07058 💬 Acamprosate [2]  6 , 206 💬
35 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00777 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
36 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
37 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
38 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
39 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
40 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine [3]  2 ,  4 , 70 💬
41 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00711 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
42 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
43 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
44 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D04905 💬 Memantine [7]  2 ,  6 ,  8 , 13, 49, 127, 205 💬
45 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [7]  2 ,  6 ,  8 , 13, 49, 127, 205 💬