Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Renal cell carcinoma 💬
[1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
2 Renal cell carcinoma 💬
[2] BRAF, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
3 Renal cell carcinoma 💬
[2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
4 Renal cell carcinoma 💬
[2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
5 Renal cell carcinoma 💬
[2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
6 Renal cell carcinoma 💬
[2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
7 Renal cell carcinoma 💬
[2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
8 Renal cell carcinoma 💬
[1] MET 💬 D10062 💬 Cabozantinib [1] 34 💬
9 Renal cell carcinoma 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
10 Renal cell carcinoma 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
11 Renal cell carcinoma 💬
[3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [4] 51, 85, 222, 274 💬
12 Renal cell carcinoma 💬
[1] VEGFA 💬 D09574 💬 Aflibercept [2] 90, 166 💬
13 Renal cell carcinoma 💬
[1] VEGFA 💬 D06409 💬 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
14 Renal cell carcinoma 💬
[1] VEGFA 💬 D05697 💬 Ranibizumab [4] 34, 166, 227, 301 💬