Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
2 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D03658 💬 Dasatinib [2] 51, 85 💬
3 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D06414 💬 Dasatinib [2] 51, 85 💬
4 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
5 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
6 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
7 Chronic myeloid leukemia 💬
 [1] ABL1 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
8 Chronic myeloid leukemia 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
9 Chronic myeloid leukemia 💬
 [2] BRAF, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
10 Chronic myeloid leukemia 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
11 Chronic myeloid leukemia 💬
 [2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
12 Chronic myeloid leukemia 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [3] 19, 75, 96 💬
13 Chronic myeloid leukemia 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
14 Chronic myeloid leukemia 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
15 Chronic myeloid leukemia 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
16 Chronic myeloid leukemia 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
17 Chronic myeloid leukemia 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
18 Chronic myeloid leukemia 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
19 Chronic myeloid leukemia 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
20 Chronic myeloid leukemia 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
21 Chronic myeloid leukemia 💬
 [3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [4] 51, 85, 222, 274 💬