Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Primary immunodeficiency 💬	[1] ADA 💬	D11017 💬	Elapegademase	[1] 65 💬
2	Primary immunodeficiency 💬	[1] BTK 💬	D10893 💬	Acalabrutinib	[2] 46, 61 💬
3	Primary immunodeficiency 💬	[1] BTK 💬	D11478 💬	Branebrutinib	[3] 46, 49, 53 💬
4	Primary immunodeficiency 💬	[1] BTK 💬	D11457 💬	Fenebrutinib	[1] 13 💬
5	Primary immunodeficiency 💬	[1] BTK 💬	D10223 💬	Ibrutinib	[3] 28, 60, 61 💬
6	Primary immunodeficiency 💬	[1] BTK 💬	D12160 💬	Orelabrutinib	[3] 13, 61, 63 💬
7	Primary immunodeficiency 💬	[1] BTK 💬	D11422 💬	Zanubrutinib	[2] 300, 331 💬
8	Primary immunodeficiency 💬	[1] CD19 💬	D11757 💬	Inebilizumab	[4] 11, 13, 51, 300 💬
9	Primary immunodeficiency 💬	[2] CD3D, CD3E 💬	D05092 💬	Muromonab	[3] 60, 96, 97 💬
10	Primary immunodeficiency 💬	[2] CD3D, CD3E 💬	D08959 💬	Otelixizumab	[1] 46 💬

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