Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00636 💬 Amiodarone [2] 28, 127 💬
2 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
3 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00235 💬 Atenolol [1] 167 💬
4 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00634 💬 Bisoprolol [3] 67, 86, 113 💬
5 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [3] 67, 86, 113 💬
6 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
7 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
8 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D07660 💬 Celiprolol [1] 168 💬
9 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02349 💬 Dipivefrin [1]  6  💬
10 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
11 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
12 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
13 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
14 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
15 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00124 💬 Ephedrine [1] 11 💬
16 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00095 💬 Epinephrine [3] 46, 70, 96 💬
17 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00996 💬 Epinephrine [3] 46, 70, 96 💬
18 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02149 💬 Epinephrine [3] 46, 70, 96 💬
19 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00644 💬 Esmolol [1] 58 💬
20 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D07916 💬 Esmolol [1] 58 💬
21 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
22 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
23 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
24 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00432 💬 Nadolol [1]  6  💬
25 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05127 💬 Nebivolol [4] 17, 85, 113, 167 💬
26 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00076 💬 Norepinephrine [1] 22 💬
27 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05206 💬 Norepinephrine [1] 22 💬
28 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00483 💬 Propranolol [7]  6 , 158, 167, 215, 227, 278, 296 💬
29 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D08443 💬 Propranolol [7]  6 , 158, 167, 215, 227, 278, 296 💬
30 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00485 💬 Pseudoephedrine [1] 17 💬
31 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05648 💬 Pseudoephedrine [1] 17 💬
32 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D05649 💬 Pseudoephedrine [1] 17 💬
33 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D08449 💬 Pseudoephedrine [1] 17 💬
34 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00378 💬 Timolol [2] 157, 227 💬
35 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00603 💬 Timolol [2] 157, 227 💬
36 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D08600 💬 Timolol [2] 157, 227 💬
37 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00615 💬 Amlodipine [4] 13, 51, 67, 298 💬
38 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02914 💬 Amlodipine [4] 13, 51, 67, 298 💬
39 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07450 💬 Amlodipine [4] 13, 51, 67, 298 💬
40 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01173 💬 Cilnidipine [1] 67 💬
41 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00616 💬 Diltiazem [3] 51, 58, 86 💬
42 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D03830 💬 Diltiazem [3] 51, 58, 86 💬
43 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
44 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00349 💬 Isradipine [1]  6  💬
45 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00617 💬 Nicardipine [2] 70, 86 💬
46 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
47 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00437 💬 Nifedipine [2] 50, 81 💬
48 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01908 💬 Nilvadipine [1] 90 💬
49 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D05442 💬 Perhexiline [2] 58, 272 💬
50 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08340 💬 Perhexiline [2] 58, 272 💬
51 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
52 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
53 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00619 💬 Verapamil [3] 96, 140, 167 💬
54 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02356 💬 Verapamil [3] 96, 140, 167 💬
55 Dilated cardiomyopathy 💬
 [2] CACNA2D1, CACNA2D2 💬 D11203 💬 Mirogabalin [1] 70 💬
56 Dilated cardiomyopathy 💬
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D00332 💬 Gabapentin [5]  6 , 13, 19, 70, 298 💬
57 Dilated cardiomyopathy 💬
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D02716 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
58 Dilated cardiomyopathy 💬
 [1] DMD 💬 D11988 💬 Casimersen [1] 113 💬
59 Dilated cardiomyopathy 💬
 [1] DMD 💬 D10114 💬 Drisapersen [1] 113 💬
60 Dilated cardiomyopathy 💬
 [1] DMD 💬 D09900 💬 Eteplirsen [1] 113 💬
61 Dilated cardiomyopathy 💬
 [1] DMD 💬 D11707 💬 Golodirsen [1] 113 💬
62 Dilated cardiomyopathy 💬
 [1] DMD 💬 D11528 💬 Viltolarsen [1] 113 💬
63 Dilated cardiomyopathy 💬
 [1] ITGA4 💬 D06590 💬 Firategrast [1] 13 💬
64 Dilated cardiomyopathy 💬
 [1] ITGA4 💬 D06886 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
65 Dilated cardiomyopathy 💬
 [2] ITGA4, ITGB7 💬 D10540 💬 Abrilumab [2] 96, 97 💬
66 Dilated cardiomyopathy 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
67 Dilated cardiomyopathy 💬
 [1] ITGB7 💬 D09901 💬 Etrolizumab [2] 96, 97 💬
68 Dilated cardiomyopathy 💬
 [1] MYH7 💬 D12265 💬 Mavacamten [1] 58 💬
69 Dilated cardiomyopathy 💬
 [3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [4] 51, 85, 222, 274 💬
70 Dilated cardiomyopathy 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
71 Dilated cardiomyopathy 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
72 Dilated cardiomyopathy 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
73 Dilated cardiomyopathy 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
74 Dilated cardiomyopathy 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
75 Dilated cardiomyopathy 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
76 Dilated cardiomyopathy 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
77 Dilated cardiomyopathy 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
78 Dilated cardiomyopathy 💬
 [1] TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
79 Dilated cardiomyopathy 💬
 [1] TNF 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
80 Dilated cardiomyopathy 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬