Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Ubiquinone and other terpenoid-quinone biosynthesis 💬	[1] HPD 💬	D05177 💬	Nitisinone	[3] 6 , 164, 241 💬
2	Ubiquinone and other terpenoid-quinone biosynthesis 💬	[2] NQO1, VKORC1 💬	D00564 💬	Warfarin	[13] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
3	Ubiquinone and other terpenoid-quinone biosynthesis 💬	[2] NQO1, VKORC1 💬	D01280 💬	Warfarin	[13] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
4	Ubiquinone and other terpenoid-quinone biosynthesis 💬	[2] NQO1, VKORC1 💬	D08682 💬	Warfarin	[13] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
5	Ubiquinone and other terpenoid-quinone biosynthesis 💬	[1] VKORC1 💬	D08354 💬	Phenindione	[1] 65 💬
6	Ubiquitin mediated proteolysis 💬	[1] KEAP1 💬	D03846 💬	Dimethyl fumarate	[5] 13, 49, 51, 86, 296 💬
7	Ubiquitin mediated proteolysis 💬	[1] PML 💬	D00094 💬	Tretinoin	[6] 2 , 62, 63, 75, 94, 231 💬

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