113. Muscular dystrophy Clinical trials / Disease details


Clinical trials : 622 Drugs : 485 - (DrugBank : 99) / Drug target genes : 59 - Drug target pathways : 168

  
4 trials found
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1NCT04624750
(ClinicalTrials.gov)
September 3, 202120/10/2020Open Label Study in Adolescents and Children With Myotonic DisordersAn Open-label, Non-Comparative Study to Evaluate the Steady-State Pharmacokinetics, Safety, and Efficacy of Mexiletine in Adolescents and Children With Myotonic DisordersMyotonic DystrophyDrug: MexiletineLupin Ltd.NULLRecruiting6 Years18 YearsAll14Phase 3France
2NCT04700046
(ClinicalTrials.gov)
July 6, 20215/1/2021Study to Investigate the Efficacy and Safety of Mexiletine in Patients With Myotonic Dystrophy Type 1 and Type 2A Randomized, Double-blind, Placebo-controlled, Multi-center Study to Investigate the Efficacy and Safety of Mexiletine During 26 Weeks of Treatment in Patients With Myotonic Dystrophy Type 1 and Type 2 [The MIND Study]Myotonic Dystrophy Type 1 and Type 2Drug: Mexiletine 167 mg;Drug: PlaceboLupin Ltd.NULLNot yet recruiting18 YearsN/AAll158Phase 3NULL
3NCT04616807
(ClinicalTrials.gov)
December 17, 202023/10/2020An Observational Study in Adult Patients With Non-dystrophic Myotonic DisordersAn Observational Study to Describe the Long-term Safety and Effectiveness of Namuscla in the Symptomatic Management of Myotonia in Adult Patients With Non-dystrophic Myotonic DisordersMyotonic DystrophyDrug: MexiletineLupin Ltd.NULLRecruiting18 YearsN/AAll50France;Germany;United Kingdom
4NCT01406873
(ClinicalTrials.gov)
June 201120/7/2011Clinical Efficacy Trial of Mexiletine for Myotonic Dystrophy Type 1A Randomized, Placebo Controlled, Clinical Efficacy Trial of Mexiletine for Myotonic Dystrophy Type-1 (DM1)Myotonic DystrophyDrug: Mexiletine;Drug: PlaceboUniversity of RochesterNULLCompleted18 Years80 YearsAll42Phase 2United States