Disease details

Clinical trials : 3,342 / Drugs : 2,355 - (DrugBank : 406) / Drug target genes : 269 - Drug target pathways : 241

2 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2012-005113-39-AT (EUCTR)	08/04/2013	18/02/2013	Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve.	A Randomized, Placebo-Controlled, Double-Blind, Phase IIa Study of Amiloride in the Treatment of Acute Autoimmune Optic Neuritis - Amiloride Hydrochlorothiazide in acute autoimmune optic neuritis	Optic neuritis is among the most common first symptoms of multiple sclerosis leading to significant atrophy of the optic nerve within a short period of time, thus reflecting neurodegneration.;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Trade Name: Amilostad HCT Product Name: Amilostad HCT tablets INN or Proposed INN: AMILORIDE HYDROCHLORIDE, 2 H2O Other descriptive name: Amiloride Hydrochloride INN or Proposed INN: hydrochlorothiazide Other descriptive name: HYDROCHLOROTHIAZIDE	Universitätsklinik für Neurologie, Medizinische Universität Wien	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes		Phase 2	Austria
2	EUCTR2007-004051-11-GB (EUCTR)	18/12/2008	15/07/2008	Amiloride Treatment in Multiple Sclerosis - Amiloride in MS	Amiloride Treatment in Multiple Sclerosis - Amiloride in MS	Multiple Sclerosis	Trade Name: Amiloride Product Name: Amiloride Hydrochloride	Oxford Racliffe NHS Trust	NULL	Not Recruiting			Female: yes Male: yes	23		United Kingdom