2. Amyotrophic lateral sclerosis Clinical trials / Disease details

Clinical trials : 624 / Drugs : 611 - (DrugBank : 160) / Drug target genes : 172 - Drug target pathways : 225

21 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2019-001862-13-PT (EUCTR)	18/02/2022	21/05/2020	Evaluation of masitinib in Amyotrophic Lateral Sclerosis (ALS)	A prospective, multicenter, randomised, double-blind, placebo-controlled, parallel groups, phase 3 s ...	patients suffering from Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classific ...	Product Name: masitinib Product Code: AB1010 INN or Proposed INN: Masitinib mesylate Other descriptive n ...	ABScience	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	495	Phase 3	United States;Portugal;Slovenia;Greece;Spain;Ireland;Israel;Russian Federation;United Kingdom;Italy; ...
2	EUCTR2019-001862-13-GR (EUCTR)	03/02/2022	26/11/2021	Evaluation of masitinib in Amyotrophic Lateral Sclerosis (ALS)	A prospective, multicenter, randomised, double-blind, placebo-controlled, parallel groups, phase 3 s ...	patients suffering from Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classific ...	Product Name: masitinib Product Code: AB1010 INN or Proposed INN: Masitinib mesylate Other descriptive n ...	AB Science	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	495	Phase 3	United States;Portugal;Slovenia;Greece;Spain;Ukraine;Ireland;Austria;Russian Federation;Israel;Unite ...
3	EUCTR2019-001862-13-DK (EUCTR)	21/09/2021	30/06/2020	Evaluation of masitinib in Amyotrophic Lateral Sclerosis (ALS)	A prospective, multicenter, randomised, double-blind, placebo-controlled, parallel groups, phase 3 s ...	patients suffering from Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classific ...	Product Name: masitinib Product Code: AB1010 INN or Proposed INN: Masitinib mesylate Other descriptive n ...	AB Science	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	495	Phase 3	United States;Portugal;Slovenia;Spain;Ukraine;Ireland;Israel;Russian Federation;United Kingdom;Italy ...
4	EUCTR2019-001862-13-IT (EUCTR)	03/02/2021	06/11/2020	Evaluation of masitinib in Amyotrophic Lateral Sclerosis (ALS)	A prospective, multicenter, randomised, double-blind, placebo-controlled, parallel groups, phase 3 s ...	Patients suffering from Amyotrophic Lateral Sclerosis (ALS);Therapeutic area: Diseases [C] - Nervous ...	Product Name: Masitinib mesilate Product Code: [AB1010] INN or Proposed INN: Masitinib mesilate Other des ...	AB SCIENCE	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	495	Phase 3	United States;Portugal;Slovenia;Spain;Ukraine;Ireland;Austria;Russian Federation;Israel;United Kingd ...
5	EUCTR2019-001862-13-NO (EUCTR)	03/02/2021	20/11/2020	Evaluation of masitinib in Amyotrophic Lateral Sclerosis (ALS)	A prospective, multicenter, randomised, double-blind, placebo-controlled, parallel groups, phase 3 s ...	patients suffering from Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classific ...	Product Name: masitinib Product Code: AB1010 INN or Proposed INN: Masitinib mesylate Other descriptive n ...	ABScience	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	495	Phase 3	Portugal;United States;Slovenia;Spain;Ukraine;Ireland;Austria;Israel;Russian Federation;United Kingd ...
6	EUCTR2019-001862-13-PL (EUCTR)	01/12/2020	09/07/2020	Evaluation of masitinib in Amyotrophic Lateral Sclerosis (ALS)	A prospective, multicenter, randomised, double-blind, placebo-controlled, parallel groups, phase 3 s ...	patients suffering from Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classific ...	Product Name: masitinib Product Code: AB1010 INN or Proposed INN: Masitinib mesylate Other descriptive n ...	AB Science	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	495	Phase 3	United States;Portugal;Slovenia;Spain;Ukraine;Ireland;Austria;Russian Federation;Israel;United Kingd ...
7	EUCTR2019-001862-13-SE (EUCTR)	14/10/2020	23/03/2020	Evaluation of masitinib in Amyotrophic Lateral Sclerosis (ALS)	A prospective, multicenter, randomised, double-blind, placebo-controlled, parallel groups, phase 3 s ...	patients suffering from Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classific ...	Product Name: masitinib Product Code: AB1010 INN or Proposed INN: Masitinib mesylate Other descriptive n ...	ABScience	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	495	Phase 3	Portugal;United States;Slovenia;Spain;Ireland;Israel;Russian Federation;United Kingdom;Italy;France; ...
8	NCT03127267 (ClinicalTrials.gov)	October 1, 2020	13/4/2017	Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients	A Prospective, Multicenter, Randomised, Double-blind, Placebo-controlled, Parallel Groups, Phase 3 S ...	Amyotrophic Lateral Sclerosis	Drug: Masitinib (6.0);Drug: Riluzole;Drug: Placebo;Drug: Masitinib (4.5)	AB Science	NULL	Recruiting	18 Years	81 Years	All	495	Phase 3	United States;Germany;Canada
9	EUCTR2019-001862-13-ES (EUCTR)	15/09/2020	12/06/2020	Evaluation of masitinib in Amyotrophic Lateral Sclerosis (ALS)	A prospective, multicenter, randomised, double-blind, placebo-controlled, parallel groups, phase 3 s ...	patients suffering from Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classific ...	Product Name: masitinib Product Code: AB1010 INN or Proposed INN: Masitinib mesylate Other descriptive n ...	ABScience	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	495	Phase 3	United States;Portugal;Slovenia;Spain;Ireland;Russian Federation;Israel;United Kingdom;Italy;France; ...
10	EUCTR2019-001862-13-SI (EUCTR)	12/03/2020	19/02/2020	Evaluation of masitinib in Amyotrophic Lateral Sclerosis (ALS)	A prospective, multicenter, randomised, double-blind, placebo-controlled, parallel groups, phase 3 s ...	patients suffering from Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classific ...	Product Name: masitinib Product Code: AB1010 INN or Proposed INN: Masitinib mesylate Other descriptive n ...	ABScience	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	495	Phase 3	United States;Portugal;Slovenia;Spain;Ukraine;Ireland;Austria;Russian Federation;Israel;United Kingd ...

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