2. Amyotrophic lateral sclerosis Clinical trials / Disease details
Clinical trials : 624 / Drugs : 611 - (DrugBank : 160) / Drug target genes : 172 - Drug target pathways : 225
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04788745 (ClinicalTrials.gov) | June 29, 2021 | 2/3/2021 | Targeting Metabolic Flexibility in Amyotrophic Lateral Sclerosis (ALS) | Targeting Metabolic Flexibility in ALS (MetFlex); Safety and Tolerability of Trimetazidine for the Treatment of ALS | Amyotrophic Lateral Sclerosis;Motor Neuron Disease | Drug: Trimetazidine Dihydrochloride | The University of Queensland | FightMND;UMC Utrecht;King's College London;Julius Clinical, The Netherlands | Recruiting | 18 Years | 75 Years | All | 36 | Phase 2 | Australia;Netherlands;United Kingdom |
| 2 | EUCTR2020-005018-17-NL (EUCTR) | 14/05/2021 | 08/04/2021 | Safety and tolerability of Trimetazidine in amyotrophic lateral sclerosis (ALS) | Targeting metabolic flexibility in ALS (MetFlex); Safety and tolerability of Trimetazidine for the treatment of ALS - MetFlex | Patients suffering from amyotrophic lateral sclerosis (ALS);Therapeutic area: Diseases [C] - Nervous System Diseases [C10] | Trade Name: Vastarel Product Name: Trimetazidine Product Code: 201600930 | The University of Queensland | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 36 | Phase 2 | Australia;Netherlands |