203. 22q11.2 deletion syndrome Clinical trials / Disease details
Clinical trials : 5 / Drugs : 7 - (DrugBank : 1) / Drug target genes : 14 - Drug target pathways : 23
Showing 1 to 5 of 5 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | EUCTR2021-002011-61-NL (EUCTR) | 13/08/2021 | 21/06/2021 | Riluzole as treatment for psychotic and cognitive symptoms in 22q11.2 deletion syndrome | The glutamate/GABA balance as novel therapeutic target for psychotic and cognitive symptoms in 22q11.2 deletion syndrome - Riluzole in 22q11.2DS The glutamate/GABA balance as novel therapeutic target for psychotic and cognitive symptoms in 22q11 ... | 22q11.2 deletion syndrome;Therapeutic area: Psychiatry and Psychology [F] - Mental Disorders [F03] | Trade Name: Rilutek Product Name: Riluzole Product Code: EMEA/H/C/000109 | Academisch ziekenhuis Maastricht | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 45 | Phase 3 | Netherlands | ||
2 | NCT05149898 (ClinicalTrials.gov) | March 3, 2020 | 5/10/2021 | Open-Label, Tolerability and Efficacy Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With 22q11.2 Deletion Syndrome Open-Label, Tolerability and Efficacy Study of ZYN002 Administered as a Transdermal Gel to Children ... | Open-Label, Tolerability and Efficacy Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With 22q11.2 Deletion Syndrome Open-Label, Tolerability and Efficacy Study of ZYN002 Administered as a Transdermal Gel to Children ... | 22Q Deletion Syndrome | Drug: ZYN002 | Zynerba Pharmaceuticals, Inc. | NULL | Recruiting | 4 Years | 17 Years | All | 20 | Phase 1/Phase 2 | United States;Australia |
3 | NCT04639960 (ClinicalTrials.gov) | September 29, 2017 | 3/11/2020 | Neuroprotective Effects of Risperdal on Brain and Cognition in 22q11 Deletion Syndrome | Effects of Modulation of the Dopaminergic System Using Risperidone on Memory and Executive Processes in Individuals With 22q11.2 Deletion Syndrome Effects of Modulation of the Dopaminergic System Using Risperidone on Memory and Executive Processes ... | 22q11.2 Deletion Syndrome | Drug: Risperdal;Drug: Placebo | University of Geneva, Switzerland | NULL | Recruiting | 11 Years | 25 Years | All | 30 | N/A | Switzerland |
4 | NCT02895906 (ClinicalTrials.gov) | November 28, 2016 | 29/8/2016 | Safety and Efficacy Study of NFC-1 in Subjects Aged 12-17 Years With 22q11.2DS & Associated Neuropsychiatric Conditions Safety and Efficacy Study of NFC-1 in Subjects Aged 12-17 Years With 22q11.2DS & Associated Neuropsy ... | A 5-Week, Multi-center, Open-label Study to Assess the Safety and Efficacy of NFC-1 in Subjects Aged 12-17 Years With 22q11.2 Deletion Syndrome and Commonly Associated Neuropsychiatric Conditions (Anxiety, ADHD, ASD) A 5-Week, Multi-center, Open-label Study to Assess the Safety and Efficacy of NFC-1 in Subjects Aged ... | 22q11.2 Deletion Syndrome | Drug: NFC-1 | Aevi Genomic Medicine | NULL | Completed | 12 Years | 17 Years | All | 2 | Phase 1 | United States |
5 | NCT04647500 (ClinicalTrials.gov) | August 26, 2016 | 3/11/2020 | Effects of Methylphenidate on Brain and Cognition in 22q11 Deletion Syndrome | Effects of Modulation of the Dopaminergic System Using Methylphenidate on Memory and Executive Processes in Individuals With 22q11.2 Deletion Syndrome Effects of Modulation of the Dopaminergic System Using Methylphenidate on Memory and Executive Proce ... | 22q11.2 Deletion Syndrome | Drug: Concerta | University of Geneva, Switzerland | NULL | Recruiting | 8 Years | 25 Years | All | 30 | N/A | Switzerland |