206. Fragile X syndrome Clinical trials / Disease details


Clinical trials : 104 Drugs : 87 - (DrugBank : 32) / Drug target genes : 54 - Drug target pathways : 79

  
1 trial found
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1EUCTR2008-003287-18-BE
(EUCTR)
17/09/200803/09/2008Functional consequences of decreased RNA expression of certain GABA(A) receptor subunits in fragile X patients using Positron Emission Tomography and [11C]flumazenil. - PET-FRAX-GABAFunctional consequences of decreased RNA expression of certain GABA(A) receptor subunits in fragile X patients using Positron Emission Tomography and [11C]flumazenil. - PET-FRAX-GABA Fragile X syndrome is the most common form of inherited mental retardation with a prevalence of 1/4000 males and 1/6000 females. Patients are characterized by a mild to severe form of cognitive impairment and light dysmorphic features. Autism-like behaviour, hyperactivity and epilepsy can also be associated with the disease. On the molecular level the disease is caused by a dynamic mutation of a CGG repeat in the 5' UTR of the FMR1 gene.Product Name: 11C-flumazenilUniversity AntwerpUniversity Hospital Leuven gasthuisbergAuthorised-recruitment may be ongoing or finishedFemale: no
Male: yes
Belgium