251. Urea cycle disorder Clinical trials / Disease details

Clinical trials : 48 / Drugs : 52 - (DrugBank : 13) / Drug target genes : 4 - Drug target pathways : 29

3 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03064048 (ClinicalTrials.gov)	September 15, 2017	10/2/2017	Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD	Effect of Nitric Oxide(NO) Supplementation on Neurocognitive Measures in Argininosuccinate Lyase Def ...	Argininosuccinate Lyase Deficiency;Urea Cycle Disorder;Urea Cycle Disorders, Inborn;Argininosuccinic ...	Dietary Supplement: Neo-ASA;Dietary Supplement: Placebo	Baylor College of Medicine	Rare Diseases Clinical Research Network;Neogenis Laboratories	Recruiting	6 Years	50 Years	All	16	N/A	United States
2	NCT02252770 (ClinicalTrials.gov)	September 2014	25/9/2014	Nitric Oxide Supplementation in Argininosuccinic Aciduria	Nitric Oxide Supplementation as a Therapeutic Intervention in Argininosuccinic Aciduria	Argininosuccinic Aciduria;Argininosuccinate Lyase Deficiency;Urea Cycle Disorders	Dietary Supplement: Nitric oxide supplement;Dietary Supplement: Placebo	Baylor College of Medicine	NULL	Completed	8 Years	64 Years	All	12	N/A	United States
3	NCT00345605 (ClinicalTrials.gov)	February 2008	26/6/2006	Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder	A Randomized, Double-Blind, Crossover Study of Sodium Phenylbutyrate and Low-Dose Arginine Compared ...	Argininosuccinic Aciduria;Amino Acid Metabolism, Inborn Errors;Urea Cycle Disorders	Drug: Sodium Phenylbutyrate;Drug: Arginine	Brendan Lee	Office of Rare Diseases (ORD);Rare Diseases Clinical Research Network;Eunice Kennedy Shriver Nationa ...	Completed	5 Years	N/A	All	12	Phase 2	United States

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