271. Ankylosing spondylitis Clinical trials / Disease details

Clinical trials : 563 / Drugs : 372 - (DrugBank : 72) / Drug target genes : 41 - Drug target pathways : 145

29 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04943237 (ClinicalTrials.gov)	July 1, 2019	19/6/2021	Anti-TNF Therapy and Nerve Conduction Studies in Ankylosing Spondylitis	Anti-TNF Therapy and Nerve Conduction Studies in Patients With Ankylosing Spondylitis	Anti - TNF Therapy;Ankylosing Spondylitis;Neuropathy	Drug: Anti-TNF agents;Drug: Conventional therapy users for the last 5 years	Istanbul Physical Medicine Rehabilitation Training and Research Hospital	NULL	Completed	20 Years	65 Years	All	60		Turkey
2	NCT03733925 (ClinicalTrials.gov)	January 7, 2019	5/11/2018	A Study of Golimumab in the Treatment of Indian Participants With Active Spondyloarthropathy of Anky ...	A Phase-IV, Multicenter, Noncomparative, Open-Label Study Evaluating the Safety and Efficacy of Goli ...	Spondylitis, Ankylosing;Arthritis, Psoriatic	Drug: Golimumab	Johnson & Johnson Private Limited	NULL	Completed	18 Years	N/A	All	100	Phase 4	India
3	NCT03470688 (ClinicalTrials.gov)	March 1, 2018	6/3/2018	Investigating the Utilisation and Effectiveness of Originator and Biosimilar Anti-TNF Agents	An Observational Study Designed to Investigate the Utilisation and Effectiveness of Originator and B ...	Rheumatoid Arthritis;Psoriatic Arthritis;Ankylosing Spondylitis	Biological: Originator;Biological: Biosimilar	Opal Rheumatology Ltd.	Merck Sharp & Dohme Corp.	Recruiting	18 Years	N/A	All	5000		Australia
4	NCT02758782 (ClinicalTrials.gov)	September 2016	20/4/2016	NSAIDs Added to Anti-TNFTherapy Versus Anti-TNFTherapy Alone on Progression of Structural Damage in ...	COmparison of the Effect of Treatment With NSAIDs Added to Anti-TNFTherapy Versus Anti-TNFTherapy Al ...	Ankylosing Spondylitis	Biological: Golimumab;Drug: Celecoxib	Charite University, Berlin, Germany	NULL	Completed	18 Years	N/A	All	156	Phase 4	Germany
5	EUCTR2016-000615-33-DE (EUCTR)	29/07/2016	06/07/2016	Comparison of the effect of treatment with NSAIDs added to anti-TNFtherapy versus anti-TNFtherapy al ...	Comparison of the effect of treatment with NSAIDs added to anti-TNFtherapy versus anti-TNFtherapy al ...	ankylosing spondylitis (AS) MedDRA version: 21.1;Level: LLT;Classification code 10041672;Term: Spond ...	Trade Name: Simponi Trade Name: Celebrex	Charite Universitaetsmedizin	NULL	Not Recruiting			Female: yes Male: yes	170	Phase 4	Germany
6	NCT02538341 (ClinicalTrials.gov)	May 2016	18/8/2015	Safety and Effectiveness of Live Zoster Vaccine in Anti-Tumor Necrosis Factor (TNF) Users (VERVE Tri ...	Safety and Effectiveness of Live Zoster Vaccine in Anti-TNF Users (VERVE Trial)	Rheumatoid Arthritis;Inflammatory Arthritis;Arthritis;Psoriatic Arthritis;Psoriasis;Ankylosing Spond ...	Biological: Herpes Zoster Vaccine;Drug: Placebo	University of Alabama at Birmingham	Oregon Health and Science University	Active, not recruiting	50 Years	N/A	All	617	Phase 2	United States
7	NCT02469753 (ClinicalTrials.gov)	October 23, 2015	9/6/2015	Interest of Continuous Non-Steroidal Anti-Inflammatory Drug Treatment in Ankylosing Spondylitis Pati ...	Interest of Continuous Non-Steroidal Anti-Inflammatory Drug Treatment in Ankylosing Spondylitis Pati ...	Ankylosing Spondylitis	Drug: NSAIDs;Drug: anti-TNF	University Hospital, Bordeaux	NULL	Recruiting	18 Years	N/A	All	225	Phase 3	France;Monaco
8	EUCTR2015-002284-42-FI (EUCTR)	18/09/2015	28/08/2015	The rationale for this study is to gain insight in the extent and impact of immunogenicityof TNF inh ...	INTENT: immunogenicity in patients failing response on anti-TNF-Immunogenicity and pharmacokinetics ...	rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and psoriasis.;Therapeutic area: N ...	Trade Name: Enbrel Product Name: etanercept Trade Name: Humira Product Name: adalimumab Trade Name: Cimz ...	READE	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1650	Phase 1	Finland
9	NCT02492217 (ClinicalTrials.gov)	May 2015	3/7/2015	Biomarkers Identification of Anti-tumor Necrosis Factor (TNF) a Agent's Efficacy in Ankylosing Spond ...	Biomarkers Identification of Anti-TNFa Agent's Efficacy in Ankylosing Spondylitis Patients Using a T ...	Ankylosing Spondylitis	Drug: Adalimumab	Universidade Nova de Lisboa	NULL	Completed	18 Years	75 Years	All	69	Phase 4	Portugal
10	EUCTR2014-000241-74-DE (EUCTR)	30/12/2014	01/10/2014	A Study of Golimumab in Participants with Active Ankylosing Spondylitis	A Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Golimumab, an Anti-TNFa Monoclo ...	Ankylosing spondylitis (AS) MedDRA version: 19.0;Level: PT;Classification code 10002556;Term: Ankylo ...	Product Name: golimumab INN or Proposed INN: GOLIMUMAB Other descriptive name: Human anti-TNFa monoclo ...	Janssen Biologics, BV	NULL	Not Recruiting			Female: yes Male: yes	200	Phase 3	United States;Mexico;Canada;Poland;Brazil;Ukraine;Romania;Australia;Russian Federation;Germany;Korea ...

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