291. Hirschsprung disease, entire colon type Clinical trials / Disease details

Clinical trials : 14 / Drugs : 35 - (DrugBank : 15) / Drug target gene : 0 - Drug target pathway : 0

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04904081 (ClinicalTrials.gov)	June 16, 2021	14/5/2021	Feasibility of Use of Indocyanine Green in Pediatric Colorectal Surgery	The Use of Indocyanine Green Angiography in Pediatric Colorectal Surgery: A Feasibility Randomized C ...	Hirschsprung Disease;Anorectal Malformations	Drug: Indocyanine green	Lawson Health Research Institute	NULL	Recruiting	1 Month	7 Years	All	12	Phase 3	Canada
2	NCT04624334 (ClinicalTrials.gov)	February 25, 2021	29/10/2020	Non-invasive Assessment of Colonic Motility	Electro-Entero-Graphy (EEnG) for Non-invasive Diagnosis of Motility Disorders of the Bowel	Colon Disease;Functional Constipation;Electroenterography;Slow Transit;Hirschsprung Disease	Other: Elektro-Entero-Graphy procedure;Other: EEnG Questionnaire;Other: Gold Standard Questionnaire	Radboud University	NULL	Recruiting	N/A	N/A	All	80		Netherlands
3	NCT04598841 (ClinicalTrials.gov)	January 1, 2021	18/10/2020	Nutrition Support for Hirschsprung Disease	A Multicentric Study on Perioperative Nutritional Support for Hirschsprung's Disease	Nutrition Supporting;Hirschsprung Disease;Infants;Prospective Study	Dietary Supplement: supplement nutritional supporting	Tongji Hospital	NULL	Recruiting	N/A	2 Years	All	1000		China
4	ChiCTR2000035860	2020-10-01	2020-08-18	Artificial intelligence for pathological grading system of ganglion cells for intraoperative rapid b ...	Artificial intelligence for pathological grading system of ganglion cells for intraoperative rapid b ...	Hirschsprung disease	GoldStandard:The speciemens and sections will be reveiwed by three senior pediatric gastroenterology ...	Xinhua Hospital, Shanghai Jiaotong University School of Medicine	NULL	Pending	0	16	Both	Target condition:138;Difficult condition:138		China
5	NCT04020939 (ClinicalTrials.gov)	March 16, 2020	2/7/2019	The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery ...	The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery ...	Intestinal Atresia;Necrotizing Enterocolitis;Hirschsprung Disease;Gastroschisis;Intestinal Obstructi ...	Device: SPY imaging;Drug: Indocyanine Green	St. Justine's Hospital	NULL	Completed	N/A	16 Years	All	35	N/A	Canada
6	NCT03660176 (ClinicalTrials.gov)	January 2, 2019	4/9/2018	Effects of Butyrate Enemas on Postoperative Intestinal Mobility Disorders in Hirschsprung's Disease	Effects of Butyrate Enemas on Postoperative Intestinal Mobility Disorders in Hirschsprung's	Hirschsprung's Disease	Drug: butyrate enemas + routine management;Other: routine management	Assistance Publique Hopitaux De Marseille	NULL	Not yet recruiting	N/A	17 Years	All	58	Phase 3	France
7	NCT03593252 (ClinicalTrials.gov)	September 1, 2018	22/5/2018	Bowel Preparation in Elective Pediatric Intestinal Surgery	Mechanical Bowel Prep and Prophylactic Oral Antibiotic Use in Children: Implications for Intestinal ...	Colostomy Stoma;Ileostomy - Stoma;Jejunostomy Stoma;Hirschprung's Disease;NEC;Inflammatory Bowel Dis ...	Drug: Senna;Drug: Sodium Picosulfate, Magnesium Oxide and Citric Acid;Drug: Erythromycin;Drug: Kanam ...	McMaster University	NULL	Not yet recruiting	6 Months	18 Years	All	48	N/A	NULL
8	JPRN-UMIN000024993	2016/12/01	15/12/2016	Study for efficacy of usage of enteral nutrient with immuno-balance modulation action in perioperati ...		Hirschsprung's disease, Atresia ani, Congenital biliary dilatation, GERD	In the control group, the following enteral nutrient will be administered (breast milk or artificial ...	University of Tsukuba Hospital	NULL	Pending	6months-old	48months-old	Male and Female	10	Not applicable	Japan
9	NCT02343562 (ClinicalTrials.gov)	October 2014	9/1/2015	Probiotics for Prophylaxis of Postoperative Hirschsprungs Associated Enterocolitis	Probiotics for Prophylaxis of Postoperative Hirschsprungs Associated Enterocolitis	Hirschsprung Disease	Dietary Supplement: Probiotics;Dietary Supplement: Placebo	Cairo University	NULL	Unknown status	6 Months	12 Years	All	40	Phase 4	Egypt
10	NCT02350088 (ClinicalTrials.gov)	January 2014	17/1/2015	Fast-track Surgery in the Treatment of Hirschsprung's Disease	Fast-track Surgery in the Treatment of Hirschsprung's Disease	Surgery	Drug: probiotics;Drug: placebo	Tongji Hospital	Children's Hospital Boston	Recruiting	1 Year	18 Years	Both	100	N/A	China

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