298. Hereditary pancreatitis Clinical trials / Disease details
Clinical trials : 98 / Drugs : 180 - (DrugBank : 57) / Drug target genes : 53 - Drug target pathways : 142
Showing 1 to 10 of 98 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05270434 (ClinicalTrials.gov) | March 1, 2022 | 10/1/2022 | Optimal Timing of Endoscopic Intervention in the Treatment of Chronic Pancreatitis. | Optimal Timing of Endoscopic Intervention After Extracorporeal Shock-Wave Lithotripsy in the Treatment of Chronic Pancreatitis With Pancreatic Stones. Optimal Timing of Endoscopic Intervention After Extracorporeal Shock-Wave Lithotripsy in the Treatme ... | Pancreatitis, Chronic | Procedure: time interval between ESWL and ERCP is 12h;Procedure: time interval between ESWL and ERCP is 12-36h;Procedure: time interval between ESWL and ERCP is greater than 36h;Drug: morphine, buprenorphine, pethidine, tramaldol, metamizole and acetylsalicylacid (Analgesics) Procedure: time interval between ESWL and ERCP is 12h;Procedure: time interval between ESWL and ERCP ... | Changhai Hospital | NULL | Not yet recruiting | 18 Years | 75 Years | All | 225 | N/A | China |
2 | NCT05261997 (ClinicalTrials.gov) | March 2022 | 24/11/2021 | Endotherapy for Painless Chronic Pancreatitis | Effect of Endotherapy on the Progression of Chronic Pancreatitis in Painless Patients | Pancreatitis, Chronic;Exocrine Pancreatic Insufficiency;Abdominal Pain;Cholangiopancreatography, Endoscopic Retrograde Pancreatitis, Chronic;Exocrine Pancreatic Insufficiency;Abdominal Pain;Cholangiopancreatography, End ... | Procedure: extracorporeal shock wave lithotripsy and endoscopic drainage of the main pancreatic duct;Drug: pancreatic enzyme(Pancreatin Enteric-coated Capsules or Oryz-Aspergillus Enzyme and Pancreatin Table), antidiabetic medicine(Acarbose Tablets, Glucophage, Glimepirde Tablets) Procedure: extracorporeal shock wave lithotripsy and endoscopic drainage of the main pancreatic duct ... | Changhai Hospital | NULL | Recruiting | 18 Years | 70 Years | All | 60 | N/A | China |
3 | NCT05095532 (ClinicalTrials.gov) | December 1, 2021 | 11/10/2021 | Autologous Mesenchymal Stromal Cells and Islet Co-transplantation in TP-IAT | Autologous Mesenchymal Stromal Cells and Islet Co-transplantation to Enhance Islet Survival and Function in Chronic Pancreatitis Patients Undergo Total Pancreatectomy and Islet Autotransplantation Autologous Mesenchymal Stromal Cells and Islet Co-transplantation to Enhance Islet Survival and Func ... | Chronic Pancreatitis;Mesenchymal Stem Cells | Biological: Bone marrow-derived mesenchymal stem cells;Other: Placebo | Medical University of South Carolina | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Recruiting | 18 Years | N/A | All | 42 | Phase 1 | United States |
4 | NCT05069597 (ClinicalTrials.gov) | October 14, 2021 | 27/9/2021 | Study to Evaluate Symptoms of Exocrine Pancreatic Insufficiency in Adult Participants With Cystic Fibrosis or Chronic Pancreatitis Treated With Creon Study to Evaluate Symptoms of Exocrine Pancreatic Insufficiency in Adult Participants With Cystic Fi ... | A Phase 4 Study to Assess Symptoms of Exocrine Pancreatic Insufficiency in Subjects With Cystic Fibrosis or Chronic Pancreatitis Treated With Creon® (Pancrelipase) With an Alternate Source of Active Pharmaceutical Ingredient A Phase 4 Study to Assess Symptoms of Exocrine Pancreatic Insufficiency in Subjects With Cystic Fibr ... | Cystic Fibrosis;Chronic Pancreatitis | Drug: CREON | AbbVie | NULL | Recruiting | 18 Years | N/A | All | 30 | Phase 4 | United States |
5 | NCT04949828 (ClinicalTrials.gov) | September 16, 2021 | 21/6/2021 | Effect of CREON on Exocrine Pancreatic Insufficiency (EPI) Symptoms | Observational Study Assessing for Effect of CREON on Symptoms of Exocrine Pancreatic Insufficiency (EPI) in Patients With EPI Due to Chronic Pancreatitis (CP) Observational Study Assessing for Effect of CREON on Symptoms of Exocrine Pancreatic Insufficiency ( ... | Chronic Pancreatitis | Drug: CREON | AbbVie | NULL | Recruiting | 18 Years | N/A | All | 90 | United States | |
6 | NCT04611958 (ClinicalTrials.gov) | July 1, 2021 | 27/10/2020 | Intraductal Liposomal Bupivacaine for Chronic Pancreatitis | Intraductal Liposomal Bupivacaine as a Therapeutic Trial to Determine the Contribution of Peripheral Versus Central Sensitization in the Pathogenesis of Pain in Chronic Pancreatitis- a Pilot and Feasibility Study Intraductal Liposomal Bupivacaine as a Therapeutic Trial to Determine the Contribution of Peripheral ... | Chronic Pancreatitis | Drug: ERCP with Bupivacaine infusion | Johns Hopkins University | NULL | Withdrawn | 18 Years | 80 Years | All | 0 | Early Phase 1 | United States |
7 | ChiCTR2000037002 | 2020-10-01 | 2020-08-26 | Differential diagnosis of pancreatic cancer and chronic pancreatitis with serum miR-25 | A prospective study of serum miR-25 detection in differential diagnosis of pancreatic cancer and chronic pancreatitis A prospective study of serum miR-25 detection in differential diagnosis of pancreatic cancer and chr ... | pancreatic cancer | Gold Standard:Pancreatic cancer: pancreatic ductal adenocarcinoma originating from pancreatic ductal epithelium was confirmed by pathological examination (operative biopsy, puncture biopsy, cytological examination). Chronic pancreatitis: Clinically diagnosed as chronic pancreatitis, and no evidence to support the diagnosis of pancreatic cancer.;Index test:Serum miR-25; GoldStandard:Pancreatic cancer: pancreatic ductal adenocarcinoma originating from pancreatic ductal ... | The First Affiliated Hospital of the Naval Medical University of the Chinese People's Liberation Army The First Affiliated Hospital of the Naval Medical University of the Chinese People's Liberation Arm ... | NULL | Pending | 18 | 75 | Both | Target condition:150;Difficult condition:150 | China | |
8 | NCT04207060 (ClinicalTrials.gov) | July 15, 2020 | 17/12/2019 | Trial of Indomethacin in Chronic Pancreatitis | Phase 1/2 Trial of Indomethacin in Chronic Pancreatitis (The PAIR Trial) | Chronic Pancreatitis | Drug: Indomethacin;Drug: Placebos | Mayo Clinic | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Recruiting | 18 Years | 60 Years | All | 32 | Phase 2 | United States |
9 | NCT04315311 (ClinicalTrials.gov) | May 6, 2020 | 18/3/2020 | Study Of Effects Of Oral CREON Capsules In Adult Participants With Exocrine Pancreatic Insufficiency Not Due To Cystic Fibrosis, Chronic Pancreatitis, Pancreatectomy, Or Pancreatic Cancer Study Of Effects Of Oral CREON Capsules In Adult Participants With Exocrine Pancreatic Insufficiency ... | A Phase 4 Open-Label Single-Arm Study To Evaluate The Use Of CREON In Subjects With EPI Due To Etiologies Other Than Cystic Fibrosis, Chronic Pancreatitis, Pancreatectomy, Or Pancreatic Cancer A Phase 4 Open-Label Single-Arm Study To Evaluate The Use Of CREON In Subjects With EPI Due To Etiol ... | Exocrine Pancreatic Insufficiency (EPI) | Drug: CREON | AbbVie | NULL | Withdrawn | 18 Years | N/A | All | 0 | Phase 4 | United States |
10 | NCT03568630 (ClinicalTrials.gov) | July 26, 2018 | 13/6/2018 | Blood Markers of Early Pancreas Cancer | A Longitudinal Cohort Study to Identify Clinical and Blood Markers of Early Pancreas Cancer | Diabetes Mellitus, Type 2;PreDiabetes;Pancreas Cyst;Chronic Pancreatitis;Genetic Predisposition to Disease;Inherited Disease Diabetes Mellitus, Type 2;PreDiabetes;Pancreas Cyst;Chronic Pancreatitis;Genetic Predisposition to D ... | Diagnostic Test: Mixed Meal Tolerance Test;Diagnostic Test: Hemoglobin A1c;Diagnostic Test: Other exploratory blood biomarkers Diagnostic Test: Mixed Meal Tolerance Test;Diagnostic Test: Hemoglobin A1c;Diagnostic Test: Other ex ... | University of Nebraska | National Cancer Institute (NCI);Virginia Mason Hospital/Medical Center;VA Nebraska Western Iowa Health Care System National Cancer Institute (NCI);Virginia Mason Hospital/Medical Center;VA Nebraska Western Iowa Heal ... | Recruiting | 19 Years | N/A | All | 1250 | United States |