49. Systemic lupus erythematosus Clinical trials / Disease details


Clinical trials : 946 Drugs : 722 - (DrugBank : 186) / Drug target genes : 117 - Drug target pathways : 199

  
2 trials found
No.TrialIDDate_
enrollment
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agemin
Inclusion_
agemax
Inclusion_
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PhaseCountries
1NCT05063513
(ClinicalTrials.gov)
July 20096/5/2009Autologous Stem Cell Transplantation: International Lupus TrialRemission Induction Therapy for Refractory Systemic Lupus Erythematosus With Autologous Hematopoietic Stem Cell Transplantation (AHSCT) Versus Rituximab (antiCD20) Followed by Maintenance Therapy With Mycophenolate Mofetil (MMF)REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUSBiological: Autologous Hematopoietic Stem Cell Transplantation;Drug: RituximabEuropean Society for Blood and Marrow TransplantationEULARWithdrawn16 Years60 YearsAll0Phase 2/Phase 3France
2NCT00076752
(ClinicalTrials.gov)
January 30, 20042/2/2004Lymphocyte Depletion and Stem Cell Transplantation to Treat Severe Systemic Lupus ErythematosusA Pilot Study of Intensified Lymphodepletion Followed by Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Systemic Lupus ErythematosusLupus Erythematosus, SystemicDrug: fludarabine phosphate;Drug: cyclophosphamide;Biological: Rituxan (rituximab);Biological: filgrastim;Drug: methylprednisolone;Other: immunologic technique;Other: laboratory biomarker analysis;Procedure: autologous hematopoietic stem cell transplantation;Drug: Diphenhydramine;Drug: MesnaNational Cancer Institute (NCI)NULLCompleted15 Years40 YearsAll9Phase 2United States