49. Systemic lupus erythematosus Clinical trials / Disease details

Clinical trials : 946 / Drugs : 722 - (DrugBank : 186) / Drug target genes : 117 - Drug target pathways : 199

20 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04702256 (ClinicalTrials.gov)	December 9, 2021	30/11/2020	Induction Therapy for Lupus Nephritis With no Added Oral Steroids: An Open Label Randomised Multicen ...	Induction Therapy for Lupus Nephritis With no Added Oral Steroids: An Open Label Randomised Multicen ...	Lupus Nephritis;Systemic Lupus Erythematosus (SLE)	Drug: Obinutuzumab administration;Drug: Administration of Methylprednisolone + Prednisone + Mycopheno ...	Assistance Publique - Hôpitaux de Paris	Roche Pharma AG	Recruiting	14 Years	N/A	All	196	Phase 3	France
2	NCT05057481 (ClinicalTrials.gov)	September 15, 2021	16/9/2021	Reappraisal of the Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Erythematos ...	Reappraisal of Second-line Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Ery ...	Autoimmune Hemolytic Anemia;Systemic Lupus Erythematosus	Drug: Mycophenolate Mofetil 500mg;Drug: Rituximab	Assiut University	NULL	Active, not recruiting	18 Years	N/A	All	30	Phase 3	Egypt
3	NCT03492255 (ClinicalTrials.gov)	April 12, 2018	16/3/2018	CYCLONES - CYClophosphamide LOw Dose and No Extra Steroid	CYCLONES - CYClophosphamide LOw Dose and No Extra Steroid	Systemic Lupus Erythematosus (SLE)	Drug: Cyclophosphamide;Drug: Methylprednisolone;Drug: Prednisone;Drug: Mycophenolate Mofetil	University of Sao Paulo General Hospital	Fundação de Amparo à Pesquisa do Estado de São Paulo	Terminated	18 Years	N/A	All	49	N/A	Brazil
4	NCT02080195 (ClinicalTrials.gov)	September 13, 2016	28/2/2014	Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythe ...	A Phase I/II Study of Nonmyeloablative Conditioning and Transplantation of Human Leukocyte Antigen ( ...	Lupus Erythematosus;Graft-versus-host Disease	Drug: Cyclophosphamide;Drug: Fludarabine;Drug: Tacrolimus;Drug: Mycophenolate Mofetil;Drug: Rabbit ant ...	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Maryland Stem Cell Research Fund	Terminated	18 Years	75 Years	All	1	Phase 1/Phase 2	United States
5	JPRN-UMIN000025328	2015/12/05	25/12/2016	A Randomized Open-label Study to Evaluate the Efficacy and Safety of Tacrolimus and Corticosteroids ...	A Randomized Open-label Study to Evaluate the Efficacy and Safety of Tacrolimus and Corticosteroids ...	systemic lupus erythematosus	Tacrolimus Mycophenolate Mofetil	The University of Hong Kong	NULL	Recruiting	18years-old	75years-old	Male and Female	200	Not selected	Japan,Asia(except Japan)
6	NCT01773616 (ClinicalTrials.gov)	April 2015	1/11/2012	Trial of Rituximab and Mycophenolate Mofetil Without Oral Steroids for Lupus Nephritis	Phase 3 Open Label Randomised Multicentre Controlled Trial of Rituxmab and Mycophenolate MofetilWith ...	Systemic Lupus Erythematosus, Lupus Nephritis	Drug: Oral prednisolone;Drug: Rituximab;Drug: Mycophenolate mofetil;Drug: Methyl prednisolone	Imperial College London	Karolinska Institutet;Ohio State University;Dutch Working Party on Systemic Lupus Erythematosus;EULA ...	Terminated	12 Years	75 Years	All	24	Phase 3	United Kingdom
7	NCT01946880 (ClinicalTrials.gov)	November 20, 2013	13/9/2013	Randomized MMF Withdrawal in Systemic Lupus Erythematosus (SLE)	An Investigator-Initiated, Phase II, Randomized, Withdrawal Study of Mycophenolate Mofetil(MMF) in P ...	Systemic Lupus Erythematosus;SLE	Drug: Mycophenolate Mofetil;Drug: Hydroxychloroquine or Chloroquine;Drug: Prednisone	National Institute of Allergy and Infectious Diseases (NIAID)	Autoimmunity Centers of Excellence;Rho Federal Systems Division, Inc.	Terminated	18 Years	70 Years	All	102	Phase 2	United States
8	NCT01085097 (ClinicalTrials.gov)	September 1, 2010	4/3/2010	A Study of Laquinimod in Participants With Systemic Lupus Erythematosus (SLE) Active Lupus Nephritis ...	A Phase 2a, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Study to Evaluate the Safety, ...	Lupus Nephritis	Drug: Laquinimod;Drug: Mycophenolate Mofetil;Drug: Prednisolone /Prednisone;Drug: Placebo;Drug: Methyl ...	Teva Branded Pharmaceutical Products R&D, Inc.	NULL	Completed	18 Years	75 Years	All	46	Phase 2	United States;Canada;France;Russian Federation;United Kingdom
9	NCT05063513 (ClinicalTrials.gov)	July 2009	6/5/2009	Autologous Stem Cell Transplantation: International Lupus Trial	Remission Induction Therapy for Refractory Systemic Lupus Erythematosus With Autologous Hematopoieti ...	REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS	Biological: Autologous Hematopoietic Stem Cell Transplantation;Drug: Rituximab	European Society for Blood and Marrow Transplantation	EULAR	Withdrawn	16 Years	60 Years	All	0	Phase 2/Phase 3	France
10	EUCTR2005-004575-37-GB (EUCTR)	14/03/2008	08/10/2008	A Phase II/III Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effi ...	A Phase II/III Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effi ...	IMMUNOSUPPRESSION FOR DISEASE, NOS MedDRA version: 9.1;Level: LLT;Classification code 10025139;Term: ...	Trade Name: Orencia Product Name: Abatacept Product Code: BMS-188667 INN or Proposed INN: Abatacept Othe ...	Bristol-Myers Squibb International Corporation	NULL	Not Recruiting			Female: yes Male: yes	460	Phase 2;Phase 3	France;Belgium;United Kingdom

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