61. Autoimmune hemolytic anemia Clinical trials / Disease details
Clinical trials : 137 / Drugs : 127 - (DrugBank : 55) / Drug target genes : 26 - Drug target pathways : 153
Showing 1 to 10 of 137 diseases
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05073458 (ClinicalTrials.gov) | March 15, 2022 | 28/9/2021 | Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolytic Anemia Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolyt ... | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolytic Anemia A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsacli ... | Warm Autoimmune Hemolytic Anemia (wAIHA) | Drug: parsaclisinib;Drug: placebo | Incyte Corporation | NULL | Recruiting | 18 Years | 99 Years | All | 100 | Phase 3 | United States;Austria;Belgium;Canada;France;Germany;Israel;Italy;Japan;Netherlands;Poland;Spain;United Kingdom United States;Austria;Belgium;Canada;France;Germany;Israel;Italy;Japan;Netherlands;Poland;Spain;Unit ... |
| 2 | EUCTR2021-002844-66-NL (EUCTR) | 10/03/2022 | 29/11/2021 | Study of the Efficacy and Safety of Parsaclisib in Participants with Primary Warm Autoimmune Hemolytic Anemia Study of the Efficacy and Safety of Parsaclisib in Participants with Primary Warm Autoimmune Hemolyt ... | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsaclisib in Participants with Primary Warm Autoimmune Hemolytic Anemia A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsacli ... | Primary Warm Autoimmune Hemolytic Anemia MedDRA version: 20.0;Level: LLT;Classification code 10003825;Term: Autoimmune hemolytic anemia;System Organ Class: 100000004851;Therapeutic area: Diseases [C] - Immune System Diseases [C20] Primary Warm Autoimmune Hemolytic Anemia MedDRA version: 20.0;Level: LLT;Classification code 1000382 ... | Product Name: Parsaclisib (1 mg) Product Code: INCB050465 INN or Proposed INN: not yet assigned Other descriptive name: INCB050465 HYDROCHLORIDE Product Name: Parsaclisib (2.5 mg) Product Code: INCB050465 INN or Proposed INN: not yet assigned Other descriptive name: INCB050465 HYDROCHLORIDE Product Name: Parsaclisib(1 mg) Product Code: INCB050465 INN or Proposed INN: not yet assigned Other de ... | Incyte Corporation | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 100 | Phase 3 | United States;Spain;Ukraine;Austria;Israel;Italy;United Kingdom;France;Canada;Belgium;Poland;Netherlands;Germany;Japan United States;Spain;Ukraine;Austria;Israel;Italy;United Kingdom;France;Canada;Belgium;Poland;Netherl ... | ||
| 3 | NCT05221619 (ClinicalTrials.gov) | February 10, 2022 | 5/1/2022 | Post-trial Access for Nipocalimab in Participants With Warm Autoimmune Hemolytic Anemia (wAIHA) | Nipocalimab Post-trial Access in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA) Who Are Experiencing Clinical Benefit After Complete 28-Weeks Open-label Extension in MOM-M281-006 Nipocalimab Post-trial Access in Patients With Warm Autoimmune Hemolytic Anemia(wAIHA) Who Are Exper ... | Anemia, Hemolytic, Autoimmune | Drug: Nipocalimab | Janssen Research & Development, LLC | NULL | Available | N/A | N/A | All | NULL | ||
| 4 | EUCTR2021-002039-40-IT (EUCTR) | 08/02/2022 | 01/10/2021 | Basket study to assess efficacy, safety and PK of iptacopan (LNP023) in autoimmune benign hematological disorders Basket study to assess efficacy, safety and PK of iptacopan (LNP023) in autoimmune benign hematologi ... | An open-label, multi-center, phase 2 basket study to assess efficacy, safety and pharmacokinetics of iptacopan (LNP023) in participants with autoimmune benign hematological disorders - -- An open-label, multi-center, phase 2 basket study to assess efficacy, safety and pharmacokinetics of ... | Immune thrombocytopenia (ITP)Cold agglutinin disease (CAD) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immune thrombocytopenia;System Organ Class: 10005329 - Blood and lymphatic system disorders MedDRA version: 20.0;Level: LLT;Classification code 10068863;Term: Cold agglutinin disease;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Blood and lymphatic diseases [C15] Immune thrombocytopenia (ITP)Cold agglutinin disease(CAD) MedDRA version: 23.0;Level: PT;Classificat ... | Trade Name: ACT-HIB Polvere e solvente per soluzione iniettabile in siringa preriempita 0,5 ml Product Name: - Product Code: [-] INN or Proposed INN: HAEMOPHILUS INFLUENZAE Trade Name: BEXSERO – Sospensione iniettabile – Siringa preriempita Product Name: - Product Code: [-] INN or Proposed INN: VACCINO CONTRO IL MEMINGOCOCCO DI GRUPPO B Trade Name: HIBERIX - POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE PER USO INTRAMUSCOLARE 1 FLACONCINO DI POLVERE + 1 SIRINGA PRERIEMPITA DI SOLVENTE DA 0.5 ML Product Name: - Product Code: [-] INN or Proposed INN: VACCINO HAEMOPHILUS INFLUENZAE B CONIUGATO CON TOSSOIDETETANICO Trade Name: MENVEO – Polvere e soluzione per soluzione iniettabile Product Name: - Product Code: [-] INN or Proposed INN: VACCINO POLISACCARIDICO ANTI-MENINGOCOCCICO (A.C.Y E W-135) Trade Name: Nimenrix Product Name: - Product Code: [-] INN or Proposed INN: VACCINO POLISACCARIDICO ANTI-MENINGOCOCCICO (A.C.Y E W-135) Trade Name: ACT-HIBPolvere e solvente per soluzione iniettabile in siringa preriempita 0,5 ml Product ... | NOVARTIS PHARMA AG | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 30 | Phase 2 | United States;Spain;Korea, Democratic People's Republic of;Germany;United Kingdom;Italy | ||
| 5 | NCT05089227 (ClinicalTrials.gov) | February 3, 2022 | 11/10/2021 | Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Aut ... | Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Aut ... | Prolonged Anticoagulation;Venous Thromboembolic Disease;Autoimmune Hemolytic Anemia | Drug: treatment intervention;Drug: treatment standard;Biological: biological assessment | Centre Hospitalier Universitaire Dijon | NULL | Recruiting | 18 Years | N/A | All | 72 | Phase 2 | France |
| 6 | EUCTR2021-002844-66-ES (EUCTR) | 03/02/2022 | 15/10/2021 | Study of the Efficacy and Safety of Parsaclisib in Participants with Primary Warm Autoimmune Hemolytic Anemia Study of the Efficacy and Safety of Parsaclisib in Participants with Primary Warm Autoimmune Hemolyt ... | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsaclisib in Participants with Primary Warm Autoimmune Hemolytic Anemia A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsacli ... | Primary Warm Autoimmune Hemolytic Anemia MedDRA version: 20.0;Level: LLT;Classification code 10003825;Term: Autoimmune hemolytic anemia;System Organ Class: 100000004851;Therapeutic area: Diseases [C] - Immune System Diseases [C20] Primary Warm Autoimmune Hemolytic Anemia MedDRA version: 20.0;Level: LLT;Classification code 1000382 ... | Product Name: Parsaclisib (1 mg) Product Code: INCB050465 INN or Proposed INN: Parsaclisib Other descriptive name: INCB050465 HYDROCHLORIDE Product Name: Parsaclisib (2.5 mg) Product Code: INCB050465 INN or Proposed INN: Parsaclisib Other descriptive name: INCB050465 HYDROCHLORIDE Product Name: Parsaclisib(1 mg) Product Code: INCB050465 INN or Proposed INN: Parsaclisib Other descrip ... | Incyte Corporation | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 100 | Phase 3 | United States;Spain;Ukraine;Austria;Israel;United Kingdom;Italy;France;Canada;Belgium;Poland;Germany;Netherlands;Japan United States;Spain;Ukraine;Austria;Israel;United Kingdom;Italy;France;Canada;Belgium;Poland;Germany ... | ||
| 7 | NCT04956276 (ClinicalTrials.gov) | January 1, 2022 | 30/6/2021 | Subcutaneous ALXN1830 in Adult Participants With Warm Autoimmune Hemolytic Anemia | A Phase 2, Multiple Ascending Dose, Randomized, Double-Blind, Placebo-Controlled Study of ALXN1830 Administered Subcutaneously in Patients With Warm Autoimmune Hemolytic Anemia (WAIHA) A Phase 2, Multiple Ascending Dose, Randomized, Double-Blind, Placebo-Controlled Study of ALXN1830 A ... | Warm Autoimmune Hemolytic Anemia | Drug: ALXN1830;Drug: Placebo | Alexion Pharmaceuticals | NULL | Withdrawn | 18 Years | N/A | All | 0 | Phase 2 | United States |
| 8 | JPRN-jRCT2051210140 | 30/12/2021 | 24/12/2021 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolytic Anemia A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsacli ... | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolytic Anemia - PATHWAY A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Parsacli ... | Warm Autoimmune Hemolytic Anemia (wAIHA) | Group A: Parsaclisib (INCB050465) will be administered QD orally. Group B: Placebo will be administered QD orally. Group A: Parsaclisib(INCB050465) will be administered QD orally. Group B: Placebo will be administere ... | Ueda Eiji | NULL | Recruiting | >= 18age old | <= 99age old | Both | 100 | Phase 3 | U.S.A;Japan |
| 9 | NCT05086744 (ClinicalTrials.gov) | December 21, 2021 | 28/9/2021 | Basket Study to Assess Efficacy, Safety and PK of Iptacopan (LNP023) in Autoimmune Benign Hematological Disorders Basket Study to Assess Efficacy, Safety and PK of Iptacopan (LNP023) in Autoimmune Benign Hematologi ... | An Open-label, Multi-center, Phase 2 Basket Study to Assess Efficacy, Safety and Pharmacokinetics of Iptacopan (LNP023) in Participants With Autoimmune Benign Hematological Disorders An Open-label, Multi-center, Phase 2 Basket Study to Assess Efficacy, Safety and Pharmacokinetics of ... | Immune Thrombocytopenia (ITP);Cold Agglutinin Disease (CAD) | Drug: Iptacopan | Novartis Pharmaceuticals | NULL | Recruiting | 18 Years | N/A | All | 30 | Phase 2 | Germany;Spain;United Kingdom |
| 10 | NCT05002777 (ClinicalTrials.gov) | December 7, 2021 | 5/8/2021 | Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA) Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic An ... | A Multicenter, Open-label, Phase IIb Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia A Multicenter, Open-label, Phase IIb Study to Evaluate the Efficacy, Safety and Pharmacokinetics of ... | Warm Autoimmune Hemolytic Anemia (wAIHA) | Drug: rilzabrutinib | Sanofi | NULL | Recruiting | 18 Years | N/A | All | 20 | Phase 2 | United States;China;Denmark;Italy;Spain;United Kingdom |