70. Spinal stenosis Clinical trials / Disease details
Clinical trials : 96 / Drugs : 203 - (DrugBank : 60) / Drug target genes : 66 - Drug target pathways : 89
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04537026 (ClinicalTrials.gov) | June 16, 2021 | 28/8/2020 | The SAFE Trial. Sterile Amniotic Fluid Filtrate Epidural Injection. | A Phase I/II Double-Blinded Randomized Prospective Study of Sterile Amniotic Fluid Filtrate Epidural Injection for the Treatment of Lumbosacral Radicular Pain Due to Spinal Stenosis: The SAFE Trial (Improving Safety and Outcomes in the Treatment of Pain and Disability Related to Spinal Stenosis). | Lumbar Spinal Stenosis | Drug: Amniotic Fluid Allograft;Drug: Dexamethasone sodium phosphate | University of Utah | Cell Therapy & Regenerative Medicine;SKAGGs Foundation | Recruiting | 18 Years | N/A | All | 112 | Phase 1/Phase 2 | United States |
| 2 | NCT02070484 (ClinicalTrials.gov) | February 2014 | 21/2/2014 | Human Amniotic Tissue-derived Allograft, NuCel, in Posteriolateral Lumbar Fusions for Degenerative Disc Disease | Efficacy of a Human Amniotic Tissue-derived Allograft, NuCel, in Patients Undergoing Posteriolateral Lumbar Fusions for Degenerative Disc Disease | Lumbar Degenerative Disc Disease;Spinal Stenosis;Spondylolisthesis;Spondylosis;Intervertebral Disk Displacement;Intervertebral Disk Degeneration;Spinal Diseases;Bone Diseases;Musculoskeletal Diseases;Spondylolysis | Biological: NuCel;Biological: Demineralized Bone Matrix | OhioHealth | NuTech Medical, Inc | Terminated | 18 Years | 75 Years | All | 6 | N/A | United States |
| 3 | NCT01618435 (ClinicalTrials.gov) | March 2012 | 8/5/2012 | The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation in the Elderly With Spinal Stenosis Due to Degenerative Spondylolisthesis | The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation | Spinal Stenosis | Biological: i-FACTOR | Sygehus Lillebaelt | CeraPedics, Inc | Active, not recruiting | 60 Years | N/A | Both | 108 | Phase 3 | Denmark |
| 4 | NCT01097486 (ClinicalTrials.gov) | June 2010 | 30/3/2010 | Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy | Phase 2 Study Evaluating Safety and Preliminary Efficacy of NeoFuse When Combined With MasterGraft Matrix in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion With Anterior Cervical Plate Fixation | Cervical Degenerative Disc Disease;Degenerative Spondylolisthesis;Spinal Stenosis | Biological: NeoFuse;Procedure: Allograft | Mesoblast, Ltd. | NULL | Completed | 18 Years | 70 Years | All | 24 | Phase 2 | United States |