84. Sarcoidosis Clinical trials / Disease details
Clinical trials : 149 / Drugs : 227 - (DrugBank : 81) / Drug target genes : 82 - Drug target pathways : 167
Showing 1 to 10 of 149 diseases
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05247554 (ClinicalTrials.gov) | March 1, 2022 | 9/2/2022 | Randomized Controlled Trial of Hydroxychloroquine Combined With Low-dose Corticosteroid in Pulmonary Sarcoidosis Randomized Controlled Trial of Hydroxychloroquine Combined With Low-dose Corticosteroid in Pulmonary ... | Randomized Controlled Trial Testing the Effect of Hydroxychloroquine Combined With Low-dose Corticosteroid Therapy in Pulmonary Sarcoidosis Randomized Controlled Trial Testing the Effect of Hydroxychloroquine Combined With Low-dose Corticos ... | Pulmonary Sarcoidosis | Drug: Hydroxychloroquine + low-dose prednisone;Drug: Prednisone | Assistance Publique - Hôpitaux de Paris | NULL | Not yet recruiting | 18 Years | 80 Years | All | 200 | Phase 3 | NULL |
| 2 | NCT04924270 (ClinicalTrials.gov) | January 2022 | 7/6/2021 | Safety and Efficacy of Faecal Microbiota Transplantation in Treatment-naïve Patients With Newly Diagnosed Chronic Inflammatory Diseases Safety and Efficacy of Faecal Microbiota Transplantation in Treatment-naïve Patients With Newly Diag ... | Safety and Clinical Efficacy Associated With Faecal Microbiota Transplantation Performed in Treatment-naïve Patients With Newly Diagnosed Rheumatoid Arthritis, Reactive Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Gouty Arthritis, Psoriasis, Hidradenitis Suppurativa, Pulmonary Sarcoidosis, Crohn's Disease, and Ulcerative Colitis: a 52-week, Double-blind, Randomised, Placebo-controlled, Exploratory Trial Safety and Clinical Efficacy Associated With Faecal Microbiota Transplantation Performed in Treatmen ... | Rheumatoid Arthritis;Reactive Arthritis;Ankylosing Spondylitis;Psoriatic Arthritis;Gouty Arthritis;Psoriasis;Hidradenitis Suppurativa;Pulmonary Sarcoidosis;Crohn Disease;Ulcerative Colitis Rheumatoid Arthritis;Reactive Arthritis;Ankylosing Spondylitis;Psoriatic Arthritis;Gouty Arthritis;P ... | Biological: Faecal microbiota transplantation;Other: Placebo | Torkell Ellingsen | Region of Southern Denmark;University of Southern Denmark | Not yet recruiting | 18 Years | 70 Years | All | 200 | Phase 2 | NULL |
| 3 | JPRN-jRCTs011210048 | 05/11/2021 | 05/11/2021 | Cardiac Sarcoidosis Multi-Center Randomized Controlled Trial | Cardiac Sarcoidosis Multi-Center Randomized Controlled Trial - CHASM CS- RCT | Cardiac Sarcoidosis Cardiac Sarcoidosis | Subjects meeting the study inclusion/exclusion criteria will be randomized equally to receive either: 1. Prednisone 0.5 mg kg/day for 6-months (MAX dose 30 mg per day) or 2. Methotrexate 15-20 mg po, sc, or IM once a week for 6-months + Folic Acid 2 mg OD for 6 months + Prednisone 20 mg day for 1 month, then 10 mg OD for 1 month, then 5 mg OD for one month then STOP Subjects meeting the study inclusion/exclusion criteria will be randomized equally to receive either ... | Toshiyuki Nagai | NULL | Pending | >= 18age old | Not applicable | Both | 194 | Phase 3 | Canada;United States;United Kingdom;Japan |
| 4 | NCT04843891 (ClinicalTrials.gov) | September 6, 2021 | 31/3/2021 | Evaluation of PET Probe [64]Cu-Macrin in Cardiovascular Disease, Cancer and Sarcoidosis. | Preliminary Evaluation of [64Cu] Macrin in Healthy Individuals and Subjects With Cardiovascular Disease, Sarcoidosis and Malignancy. Preliminary Evaluation of [64Cu] Macrin in Healthy Individuals and Subjects With Cardiovascular Dise ... | Sarcoid;Cardiovascular Diseases;Cancer | Drug: [64]Cu Macrin | Ralph Weissleder, MD | NULL | Recruiting | 18 Years | 80 Years | All | 100 | Phase 1 | United States |
| 5 | EUCTR2017-004219-37-DE (EUCTR) | 16/03/2021 | 29/07/2020 | Influence of Inhaled Aviptadil on Cough and Quality of life in Sarcoidosis | A randomized, prospective, multicenter, controlled and double-blinded Phase II Clinical Trial to evaluate the influence of inhaled Aviptadil on Cough and Quality of Life in Sarcoidosis patients - Avisarco II A randomized, prospective, multicenter, controlled and double-blinded Phase II Clinical Trial to eva ... | Pulmonary sarcoidosis associated with cough MedDRA version: 20.0;Level: PT;Classification code 10037430;Term: Pulmonary sarcoidosis;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] Pulmonary sarcoidosisassociated with cough MedDRA version: 20.0;Level: PT;Classification code 100374 ... | Product Name: Aviptadil INN or Proposed INN: Aviptadil Other descriptive name: AVIPTADIL | Universitätsklinikum Freiburg, Leitender Ärztlicher Direktor | Universitätsklinikum Freiburg, Kaufmännische Direktorin | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 200 | Phase 2 | Germany | ||
| 6 | NCT03942211 (ClinicalTrials.gov) | February 26, 2021 | 7/5/2019 | A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Effi ... | A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study in Participants With Sarcoidosis-Associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag. A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study in Participants With Sarcoidosis-A ... | Sarcoidosis-associated Pulmonary Hypertension | Drug: Selexipag;Drug: Placebo | Actelion | NULL | Recruiting | 18 Years | 75 Years | All | 74 | Phase 2 | United States;Belgium;Brazil;Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;Czechia |
| 7 | EUCTR2018-000381-11-GB (EUCTR) | 09/11/2020 | 16/06/2020 | Study of Efficacy, Safety and Tolerability of CMK389 in Patients With Chronic Pulmonary Sarcoidosis | A subject and investigator blinded, randomized, placebo-controlled, repeat-dose, multicenter study to investigate efficacy, safety, and tolerability of CMK389 in patients with chronic pulmonary sarcoidosis A subject and investigator blinded, randomized, placebo-controlled, repeat-dose, multicenter study t ... | Chronic pulmonary sarcoidosis MedDRA version: 20.0;Level: PT;Classification code 10037430;Term: Pulmonary sarcoidosis;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] Chronic pulmonary sarcoidosis MedDRA version: 20.0;Level: PT;Classification code 10037430;Term: Pulm ... | Product Code: CMK389 INN or Proposed INN: CMK389 | Novartis Pharma AG | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 66 | Phase 2 | United States;Czech Republic;Poland;Denmark;Germany;United Kingdom | ||
| 8 | NCT04017936 (ClinicalTrials.gov) | October 23, 2020 | 9/7/2019 | Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis | Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis | Cardiac Sarcoidosis | Drug: Anakinra | Virginia Commonwealth University | American Heart Association;National Center for Advancing Translational Science (NCATS) | Recruiting | 21 Years | N/A | All | 28 | Phase 2 | United States |
| 9 | EUCTR2018-000381-11-PL (EUCTR) | 06/10/2020 | 23/07/2020 | Study of Efficacy, Safety and Tolerability of CMK389 in Patients With Chronic Pulmonary Sarcoidosis | A subject and investigator blinded, randomized, placebo-controlled, repeat-dose, multicenter study to investigate efficacy, safety, and tolerability of CMK389 in patients with chronic pulmonary sarcoidosis A subject and investigator blinded, randomized, placebo-controlled, repeat-dose, multicenter study t ... | Chronic pulmonary sarcoidosis MedDRA version: 20.0;Level: PT;Classification code 10037430;Term: Pulmonary sarcoidosis;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] Chronic pulmonary sarcoidosis MedDRA version: 20.0;Level: PT;Classification code 10037430;Term: Pulm ... | Product Code: CMK389 INN or Proposed INN: CMK389 | Novartis Pharma AG | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 66 | Phase 2 | United States;Czechia;Poland;Denmark;Germany;United Kingdom | ||
| 10 | ChiCTR2000036043 | 2020-10-01 | 2020-08-21 | A prospective, single-centre, diagnostic accuracy study of XpertMTB/RIF Ultra to differentiate atypical tuberculosis from sarcoidosis A prospective, single-centre, diagnostic accuracy study of XpertMTB/RIF Ultra to differentiate atypi ... | A prospective, single-centre, diagnostic accuracy study of XpertMTB/RIF Ultra to differentiate atypical tuberculosis from sarcoidosis A prospective, single-centre, diagnostic accuracy study of XpertMTB/RIF Ultra to differentiate atypi ... | sarcoidosis, tuberculosis | Gold Standard:Biopsy pathological specimen, and sputum AFB smear;Index test:XpertMTB/RIF Ultra; | Shanghai Pulmonary Hospital Tongji University, School of Medicine | NULL | Pending | 18 | Both | Target condition:72;Difficult condition:72 | China |