86. Pulmonary arterial hypertension Clinical trials / Disease details


Clinical trials : 1,181 Drugs : 701 - (DrugBank : 126) / Drug target genes : 105 - Drug target pathways : 192

  
1 trial found
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agemin
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1EUCTR2019-001699-12-GB
(EUCTR)
27/08/201930/07/2019Relative bioavailability study of marketed and lower dose ambrisentan in healthy adult participantsAn open-label, randomized three period cross-over relative bioavailability study to compare the pharmacokinetic parameters of a lower dose formulation of ambrisentan (GSK1325760) with marketed ambrisentan in healthy adult participants Pulmonary arterial hypertension
MedDRA version: 21.1;Level: PT;Classification code 10064911;Term: Pulmonary arterial hypertension;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Product Name: Ambrisentan Tablet
Product Code: GSK1325760
INN or Proposed INN: AMBRISENTAN
Other descriptive name: (S)-2-(4,6-dimethylpyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropanoic acid
Trade Name: Volibris
Product Name: Ambrisentan 5mg film-coated tablets [marketed product]
INN or Proposed INN: AMBRISENTAN
Other descriptive name: (S)-2-(4,6-dimethylpyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropanoic acid
GlaxoSmithKline Research and Development LtdNULLNot RecruitingFemale: yes
Male: yes
24Phase 1United Kingdom