86. Pulmonary arterial hypertension Clinical trials / Disease details


Clinical trials : 1,181 Drugs : 701 - (DrugBank : 126) / Drug target genes : 105 - Drug target pathways : 192

  
3 trials found
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1NCT01934647
(ClinicalTrials.gov)
November 22, 201330/8/2013Acute Dosing of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-003)A Non-randomized, Single-Panel, Open-Label Trial to Study the Safety, Tolerability and Pharmacodynamics of MK-8892 Acute Dosing in Subjects With Moderate to Severe Pulmonary Arterial HypertensionPulmonary Arterial HypertensionDrug: MK-8892Merck Sharp & Dohme Corp.NULLTerminated18 Years70 YearsAll7Phase 1Germany
2NCT01926509
(ClinicalTrials.gov)
November 14, 201319/8/2013Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-005)A 28-Day Multiple-Dose Titration Study to Assess the Effects of MK-8892 on Safety, Tolerability and Pharmacokinetics in Subjects With Pulmonary Arterial HypertensionPulmonary Arterial HypertensionDrug: MK-8892;Drug: Placebo for MK-8892Merck Sharp & Dohme Corp.NULLCompleted18 Years70 YearsAll23Phase 1Bulgaria;Germany;Moldova, Republic of
3NCT01798849
(ClinicalTrials.gov)
March 15, 201322/2/2013A Rising Single Dose Study of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics of MK-8892 (MK-8892-001)A Single Rising Dose Clinical Trial to Study the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK-8892Pulmonary Arterial HypertensionDrug: MK-8892;Drug: Placebo for MK-8892Merck Sharp & Dohme Corp.NULLCompleted18 Years60 YearsMale25Phase 1Belgium