94. Primary sclerosing cholangitis Clinical trials / Disease details

Clinical trials : 142 / Drugs : 113 - (DrugBank : 37) / Drug target genes : 19 - Drug target pathways : 139

9 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03710122 (ClinicalTrials.gov)	January 23, 2020	15/10/2018	Vancomycin for Primary Sclerosing Cholangitis	A Prospective, Randomized, Multi-centered, Placebo-controlled Clinical Trial of Oral Vanycomycin in ...	Primary Sclerosing Cholangitis	Drug: Vancomycin;Other: Placebo	Elizabeth Carey	Arizona State University	Recruiting	18 Years	75 Years	All	102	Phase 2/Phase 3	United States;Canada
2	NCT03046901 (ClinicalTrials.gov)	December 7, 2016	31/1/2017	Vancomycin Treatment in Recurrent PSC in Liver Transplant Patients	Oral Vancomycin Treatment in Recurrent Primary Sclerosing Cholangitis in Liver Transplant Recipients	Primary Sclerosing Cholangitis;Post- Orthotopic Liver Transplantation	Drug: Vancomycin	Ochsner Health System	NULL	Withdrawn	N/A	N/A	All	0	N/A	United States
3	NCT02605213 (ClinicalTrials.gov)	September 2015	31/10/2015	Effect and Safety of Oral Vancomycin in Primary Sclerosing Cholangitis Patients	Evaluation of Effectiveness and Safety of Oral Vancomycinin Treatment of Primary Sclerosing Cholangi ...	Primary Sclerosing Cholangitis	Drug: Vancomycin;Drug: Placebo	Tehran University of Medical Sciences	NULL	Recruiting	18 Years	60 Years	Both	30	Phase 4	Iran, Islamic Republic of
4	NCT02464020 (ClinicalTrials.gov)	July 2015	29/5/2015	A Pilot Study to Characterize Bile Acid Metabolism and Dysbiosis in Primary Sclerosing Cholangitis	A Pilot Study to Characterize Bile Acid Metabolism and Dysbiosis in Primary Sclerosing Cholangitis	Primary Sclerosing Cholangitis;Inflammatory Bowel Disease	Drug: Vancomycin	University of Minnesota	NULL	Completed	18 Years	80 Years	All	8	Phase 1	United States
5	EUCTR2009-018034-11-SE (EUCTR)	29/04/2013	21/06/2011	Open pilot study of treatment with an antibiotic called vancomycinto children and adolescents with c ...	Open pilot study of treatment with vancomycinto children and adolescents with primary sclerosing cho ...	Primary Sclerosing Cholangitis (PSC) is a progressive disease of the biliary system which might lead ...	Trade Name: Vancomycin Product Name: vancomycin Trade Name: vancomycin Product Name: Vancomycin	Karolinska Institutet	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	20		Sweden
6	NCT01802073 (ClinicalTrials.gov)	January 2012	21/2/2013	Primary Sclerosing Cholangitis With Oral Vancomycinby the Study of Its Antimicrobial and Immunomodul ...	Treatment of Primary Sclerosing Cholangitis in Inflammatory Bowel Disease Patients With Oral Vancomy ...	Primary Sclerosing Cholangitis	Drug: Oral Vancomycin	Stanford University	NULL	Completed	1 Year	N/A	All	34	Phase 3	United States
7	NCT02137668 (ClinicalTrials.gov)	July 2010	12/5/2014	Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin	The Human Gastrointestinal Tract Microbiota in the Setting of Treating Primary Sclerosing Cholangiti ...	Primary Sclerosing Cholangitis;Biliary Atresia	Drug: Oral Vancomycin	Sacramento Pediatric Gastroenterology	NULL	Recruiting	N/A	40 Years	Both	200	Phase 1	United States
8	NCT01085760 (ClinicalTrials.gov)	February 2010	10/3/2010	A Pilot Study of Vancomycin or Metronidazole in Patients With Primary Sclerosing Cholangitis	A Pilot Study of Vancomycin or Metronidazole in Patients With Primary Sclerosing Cholangitis	Primary Sclerosing Cholangitis	Drug: Vancomycin;Drug: Metronidazole	Mayo Clinic	PSC Partners Seeking a Cure Foundation	Completed	18 Years	75 Years	All	35	Phase 1	United States
9	NCT01322386 (ClinicalTrials.gov)	May 2007	10/2/2011	Gastrointestinal Microbiota in Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin	The Human Gastrointestinal Tract Microbiota in the Setting of Treating Primary Sclerosing Cholangiti ...	Primary Sclerosing Cholangitis;Biliary Atresia	Drug: Vancomycin	Stanford University	NULL	Completed	1 Month	20 Years	All	32	Phase 1	NULL

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