96. Crohn disease Clinical trials / Disease details

Clinical trials : 2,400 / Drugs : 1,391 - (DrugBank : 267) / Drug target genes : 170 - Drug target pathways : 215

74 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05040464 (ClinicalTrials.gov)	August 26, 2021	26/8/2021	Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease ...	Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease ...	Crohn Disease;Azathioprine;Methotrexate	Drug: AZA capsules;Drug: MTX;Biological: blood sample	Centre Hospitalier Universitaire, Amiens	NULL	Recruiting	18 Years	N/A	All	166	Phase 3	France
2	EUCTR2019-002942-19-DK (EUCTR)	12/03/2021	05/11/2020	Nordic study of treatment strategy in inflammatory bowel disease	NORDTREATThe Nordic IBD treatment strategy trial – a randomized controlled trial of access to a prot ...	Crohn's disease and Ulcerative colitis MedDRA version: 20.1;Level: LLT;Classification code 10045365; ...	Trade Name: Remicade INN or Proposed INN: INFLIXIMAB Trade Name: Humira INN or Proposed INN: ADALIMUMAB ...	Region Örebro län	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	250	Phase 4	Denmark
3	NCT04761952 (ClinicalTrials.gov)	February 13, 2021	14/2/2021	N-3 Polyunsaturated Fatty Acids Prevent Postoperative Recurrence of Crohn's Disease	N-3 Polyunsaturated Fatty Acids Prevent Postoperative Recurrence of Crohn's Disease:a Prospective Ra ...	Inflammatory Bowel Diseases;Crohn Disease;Polyunsaturated Acid Lipidosis	Drug: azathioprine;Drug: infliximab;Drug: N-3 Polyunsaturated Fatty Acids	Sixth Affiliated Hospital, Sun Yat-sen University	NULL	Not yet recruiting	18 Years	80 Years	All	236	N/A	NULL
4	NCT04713631 (ClinicalTrials.gov)	January 2021	3/12/2020	Safety and Efficacy of Artesunate & Curcumin in Crohn's Disease	Phase 2a Randomised Double-blind Placebo-controlled Trial to Assess Safety, Efficacy of Artesunate & ...	Crohn's Disease	Drug: Artesunate;Drug: Curcumin;Drug: Placebo A;Drug: Placebo C	Sanjay Gandhi Postgraduate Institute of Medical Sciences	St George's University of London, London, UK	Not yet recruiting	18 Years	65 Years	All	40	Phase 2	India
5	NCT03681652 (ClinicalTrials.gov)	February 11, 2019	20/9/2018	Post-Operative Crohn's Disease Outcome in Children	Post-Operative Crohn's Disease Outcome in Children (The POPCORN Trial): a Prospective Comparative No ...	Crohn Disease	Drug: Azathioprine;Drug: Anti-TNF Drug	Schneider Children's Medical Center, Israel	NULL	Recruiting	6 Years	18 Years	All	100		Israel
6	EUCTR2014-002311-41-NL (EUCTR)	25/05/2018	18/12/2017	A proSpective randomized controlled trial comParing infliximAb-antimetabolites combination therapy t ...	A proSpective randomized controlled trial comParing infliximAb-antimetabolites combination therapy t ...	Luminal Crohn’s disease patients with steroid free remission for at least 6 months and a combination ...	Trade Name: REMICADE Product Name: INFLIXIMAB Trade Name: IMUREL Product Name: azathioprine Trade Name: ...	GETAID	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	300	Phase 4	France;Belgium;Germany;Netherlands;United Kingdom;Sweden
7	NCT04160325 (ClinicalTrials.gov)	May 14, 2018	3/11/2019	Effect of the Exclusive Enteral Nutrition Combined With Azathioprine for Remission of Crohn's Diseas ...	The Effect of the Exclusive Enteral Nutrition Combined With Azathioprine in Maintaining Remission of ...	Crohn Disease	Dietary Supplement: postoperative 3-month exclusive enteral nutrition;Drug: azathioprine;Other: norm ...	Zhu Weiming	Sixth Affiliated Hospital, Sun Yat-sen University;Sir Run Run Shaw Hospital;The First Affiliated Hos ...	Recruiting	18 Years	65 Years	All	198	N/A	China
8	EUCTR2016-000522-18-BE (EUCTR)	02/05/2018	08/01/2018	Risk stratified randomized controlled trial in paediatric Crohn’s Disease: Methotrexate versus azath ...	Risk stratified randomized controlled trial in paediatric Crohn’s Disease: Methotrexate versus azath ...	Pediatric Crohn’s disease;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Product Name: humira INN or Proposed INN: ADALIMUMAB Product Name: Imurel INN or Proposed INN: azathiop ...	PIBDNet	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	312	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	France;Hungary;Czech Republic;Canada;Poland;Belgium;Israel;Netherlands;Germany;Italy;United Kingdom
9	EUCTR2016-000522-18-CZ (EUCTR)	24/04/2018	25/04/2018	Risk stratified randomized controlled trial in paediatric Crohn´s Disease: Methotrexate versus azath ...	Risk stratified randomized controlled trial in paediatric Crohn´s Disease: Methotrexate versus azath ...	Crohn's disease;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Product Name: Azathioprin INN or Proposed INN: azathioprine Other descriptive name: AZATHIOPRINE Trade ...	PIBDNet	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	312	Phase 4	France;Hungary;Czech Republic;Canada;Poland;Belgium;Israel;Netherlands;Germany;Italy;United Kingdom
10	EUCTR2016-004112-35-SE (EUCTR)	04/04/2018	21/06/2017	A comparison between standard treatment with azathioprine and a modified treatment with a lower dose ...	Low-dose azathioprine and allopurinol- versus azathioprine monotherapy in patients with Inflammatory ...	Patients with inflammatory bowel diseae (Ulcerative colitis or Crohns disease) wh do not responding ...	Trade Name: Imurel Product Name: Azathioprine Product Code: NA Trade Name: Allopurinol Product Name: All ...	SOIBD (The Swedish Organisation for the study of Inflammatory Bowel Diseases)	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	120	Phase 4	Sweden

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