96. Crohn disease Clinical trials / Disease details

Clinical trials : 2,400 / Drugs : 1,391 - (DrugBank : 267) / Drug target genes : 170 - Drug target pathways : 215

77 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04643483 (ClinicalTrials.gov)	June 2021	19/11/2020	A Study to Test Efficacy, Safety, and Pharmacokinetics of CertolizumabPegol in Children and Adolesce ...	A Phase 3, Randomized, Double-Blind, Multicenter Study Including an Active Reference Arm to Evaluate ...	Crohn's Disease	Drug: Certolizumab pegol;Drug: Adalimumab;Drug: Placebo	UCB Biopharma SRL	NULL	Withdrawn	6 Years	17 Years	All	0	Phase 3	NULL
2	NCT04163016 (ClinicalTrials.gov)	June 19, 2020	24/10/2019	A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (CertolizumabPegol) ...	A Postmarketing, Multicenter, Longitudinal, Prospective, Pharmacokinetic, Phase 1B Study in Pregnant ...	Rheumatoid Arthritis;Psoriatic Arthritis;Crohn's Disease;Axial Spondyloarthritis;Plaque Psoriasis	Drug: Pharmacokinetics of certolizumab pegol	UCB Biopharma S.P.R.L.	NULL	Recruiting	18 Years	N/A	Female	20	Phase 1	United States;Canada;France;Germany;Netherlands;Spain;Switzerland
3	NCT03559660 (ClinicalTrials.gov)	May 20, 2019	5/6/2018	CUP Certolizumab Pegol (CDP-870) in Adults Suffering From Crohn's Disease (CD)	Compassionate Use Program Certolizumab Pegol (CDP-870) in Adults Suffering From Crohn's Disease (CD)	Crohn's Disease	Drug: Certolizumab Pegol	UCB Biopharma S.P.R.L.	NULL	Available	18 Years	N/A	All			NULL
4	NCT03357471 (ClinicalTrials.gov)	November 3, 2017	23/11/2017	Study to Test the Safe and Effective Use of an e-Device for the Self-injection of CertolizumabPegol ...	A Multicenter, Open-Label Study to Evaluate the Safe and Effective Use of an Electro-Mechanical Inje ...	Moderate and Severe Active Rheumatoid Arthritis;Active Psoriatic Arthritis;Active Ankylosing Spondyl ...	Drug: e-Device	UCB Biopharma S.P.R.L.	NULL	Completed	18 Years	N/A	All	70	Phase 3	United States
5	NCT02597829 (ClinicalTrials.gov)	November 2015	27/10/2015	Does Clinical Response Correlate With Serum Certolizumab Levels?	Does Clinical Response Correlate With Serum CertolizumabLevels? A Prospective Open Label Trial of Ad ...	Crohn's Disease	Drug: Certolizumab Pegol	Shafran Gastroenterology Center	UCB Pharma;UCB Pharma	Not yet recruiting	18 Years	70 Years	Both	20	Phase 4	United States
6	NCT02154425 (ClinicalTrials.gov)	September 2014	30/5/2014	A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of ...	A Multicenter, Postmarketing Study to Evaluate the Concentration of CertolizumabPegol in the Breast ...	Axial Spondyloarthritis (AxSpA);Non-radiographic Evidence-AxSpA;Ankylosing Spondylitis;Crohn's Disea ...	Procedure: Breast milk sampling;Biological: Certolizumab Pegol	UCB BIOSCIENCES, Inc.	PPD;Parexel	Completed	18 Years	N/A	Female	17	Phase 1	United States;Netherlands;Switzerland;France
7	NCT02019602 (ClinicalTrials.gov)	January 2014	18/12/2013	A Multicener, Postmarketing Study Evaluating the Transfer of Cimzia From the Mother to the Infant Vi ...	A Multicenter Postmarketing Study to Evaluate the Placental Transfer of CertolizumabPegol in Pregnan ...	Axial Spondyloarthritis (AxSpA);Non-radiographic Evidence-AxSpA;Ankylosing Spondylitis;Crohn's Disea ...	Procedure: Blood sampling from mother;Procedure: Blood sampling from infant;Procedure: Blood samplin ...	UCB BIOSCIENCES, Inc.	PPD;Parexel	Completed	18 Years	N/A	All	37	Phase 1	United States;France;Netherlands;Switzerland
8	NCT02073526 (ClinicalTrials.gov)	May 2013	9/1/2014	Anti-TNF-alpha Trough Level Measurements in Inflammatory Bowel Disease	Anti-TNF-alpha Trough Level Measurements in Inflammatory Bowel Disease	Inflammatory Bowel Disease;Crohn's Disease;Ulcerative Colitis	Drug: Infliximab , adalimumab, certolizumab pegol	Oslo University Hospital	NULL	Completed	18 Years	N/A	Both	1230	N/A	Norway
9	NCT01817972 (ClinicalTrials.gov)	March 2013	19/3/2013	Cimzia Versus Cimzia Plus Azathioprine in the Treatment of Active Crohn's Disease	A Phase III, Randomized, Double-blind Trial in the Comparison of Cimzia Versus Cimzia Plus Azathiopr ...	Crohn's Disease	Biological: Certolizumab pegol;Drug: Azathioprine	Gastroenterology Research of America	UCB Pharma	Not yet recruiting	18 Years	70 Years	Both	65	Phase 3	United States
10	NCT01696942 (ClinicalTrials.gov)	February 2013	25/9/2012	Cimzia Versus Mesalamine for Crohn's Recurrence	Use of CertolizumabFollowing Ileocolectomy Lowers Endoscopic and Histological Recurrence Rates for C ...	Crohn's Disease	Drug: Cimzia;Drug: Mesalamine	Milton S. Hershey Medical Center	UCB Pharma	Terminated	18 Years	N/A	All	10	Phase 4	United States

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