96. Crohn disease Clinical trials / Disease details


Clinical trials : 2,400 Drugs : 1,391 - (DrugBank : 267) / Drug target genes : 170 - Drug target pathways : 215

  
7 trials found
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1EUCTR2019-002093-32-SE
(EUCTR)
24/10/201928/06/2019A randomised, open, within-patient controlled trial to evaluate the diagnostic usefulness of Computed Tomography with the new contrast agent Lumentin® 44 as compared to Magnetic Resonance Imaging in patients with small bowel Crohn’s disease.Randomised, open, non-inferiority within patient-controlled trial evaluating the diagnostic usefulness of Lumentin® 44 when used as contrast agent in CT-enterography as compared to MRI- enterography in patients with small bowel Crohn’s disease. None.Lumentin 44 is a contrast agent. The diagnostic usefulness of CT with Lumentin 44 as contrast agent as compared to MRE will be investigated in this trial.Patients with confirmed small bowel Crohn's disease referred to MRE examination will be included in the trial. Neither their medical condition nor disease will be investigated.
MedDRA version: 22.1;Level: LLT;Classification code 10011603;Term: CT scan;System Organ Class: 100000004848;Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Diagnosis [E01]
Product Name: Lumentin 44
Product Code: L 44
INN or Proposed INN: Egg Albumen Powder
Other descriptive name: EGG WHITE PROTEIN
Trade Name: Movprep
Lument ABNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
60Phase 2Sweden
2NCT03079700
(ClinicalTrials.gov)
August 1, 20129/3/2017Immune Modulation From Trichuris SuisMucosal and Systemic Immune Modulation From Trichuris Suis in a Self-infected IndividualCrohn Disease;Ulcerative Colitis;Intestinal HelminthiasisBiological: Trichuris suis eggsUniversity of AarhusNULLCompleted18 Years70 YearsMale1N/ANULL
3NCT02399683
(ClinicalTrials.gov)
February 201212/3/2015Immune Modulation From Trichuris TrichiuraMucosal and Systemic Immune Modulation From Trichuris Trichiura in a Self-infected IndividualCrohn Disease;Colitis, Ulcerative;Intestinal HelminthiasisBiological: Trichuris trichiura eggsUniversity of AarhusNULLCompleted18 Years70 YearsMale1N/ANULL
4EUCTR2006-000720-13-DE
(EUCTR)
27/10/201029/01/2010Study to evaluate the effectiveness and safety of 3 doses of embryonated eggs of the porcine whipworm compared to placebo (dummy drug) in the treatment of active Crohn's disease.Double-blind, randomised, placebo-controlled, multi-centre phase II study to evaluate the efficacy and safety of three different dosages of oral Trichuris suis ova (TSO) suspension in active Crohn’s disease - TSO vs. placebo in active Crohn’s disease Induction of remission in active Crohn´s disease
MedDRA version: 14.1;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: Suspension containing 250 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 250
Other descriptive name: Suspension containing 250 embryonated, viable TSO/15ml
Product Name: Suspension containing 2500 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 2500
Other descriptive name: Suspension containing 2500 embryonated, viable TSO/15ml
Product Name: Suspension containing 7500 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 7500
Other descriptive name: Suspension of 7500 embryonated, viable TSO/15ml
Dr. Falk Pharma GmbHNULLNot RecruitingFemale: yes
Male: yes
400Phase 2Czech Republic;Denmark;Austria;Germany;Switzerland
5EUCTR2006-000720-13-CZ
(EUCTR)
18/10/201030/06/2010Study to evaluate the effectiveness and safety of 3 doses ofembryonated eggs of the porcine whipworm compared to placebo(dummy drug) in the treatment of active Crohn's disease.Double-blind, randomised, placebo-controlled, multi-centre phase II study to evaluate the efficacy and safety of three different dosages of oral Trichuris suis ova (TSO) suspension in active Crohn’s disease - TSO vs. placebo in active Crohn’s disease Induction of remission in active Crohn´s disease
MedDRA version: 16.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: Suspension containing 250 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 250
Other descriptive name: Suspension containing 250 embryonated, viable TSO/15ml
Product Name: Suspension containing 2500 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 2500
Other descriptive name: Suspension containing 2500 embryonated, viable TSO/15ml
Product Name: Suspension containing 7500 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 7500
Other descriptive name: Suspension of 7500 embryonated, viable TSO/15ml
Dr. Falk Pharma GmbHNULLNot RecruitingFemale: yes
Male: yes
400Phase 2Czech Republic;Denmark;Austria;Germany;Switzerland
6EUCTR2006-000720-13-DK
(EUCTR)
22/06/201017/03/2010Study to evaluate the effectiveness and safety of 3 doses ofembryonated eggs of the porcine whipworm compared to placebo(dummy drug) in the treatment of active Crohn's disease.Double-blind, randomised, placebo-controlled, multi-centre phase II study to evaluate the efficacy and safety of three different dosages of oral Trichuris suis ova (TSO) suspension in active Crohn’s disease - TSO vs. placebo in active Crohn’s disease Induction of remission in active Crohn´s disease
MedDRA version: 14.1;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: Suspension containing 250 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 250
Other descriptive name: Suspension containing 250 embryonated, viable TSO/15ml
Product Name: Suspension containing 2500 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 2500
Other descriptive name: Suspension containing 2500 embryonated, viable TSO/15ml
Product Name: Suspension containing 7500 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 7500
Other descriptive name: Suspension of 7500 embryonated, viable TSO/15ml
Dr. Falk Pharma GmbHNULLNot RecruitingFemale: yes
Male: yes
400Phase 2Czech Republic;Austria;Denmark;Germany;Switzerland
7EUCTR2006-000720-13-AT
(EUCTR)
07/04/201003/03/2010Study to evaluate the effectiveness and safety of 3 doses ofembryonated eggs of the porcine whipworm compared to placebo(dummy drug) in the treatment of active Crohn's disease.Double-blind, randomised, placebo-controlled, multi-centre phase II study to evaluate the efficacy and safety of three different dosages of oral Trichuris suis ova (TSO) suspension in active Crohn’s disease - TSO vs. placebo in active Crohn’s disease Induction of remission in active Crohn´s disease
MedDRA version: 14.1;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: Suspension containing 250 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 250
Other descriptive name: Suspension containing 250 embryonated, viable TSO/15ml
Product Name: Suspension containing 2500 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 2500
Other descriptive name: Suspension containing 2500 embryonated, viable TSO/15ml
Product Name: Suspension containing 7500 embryonated, viable Trichuris suis ova (TSO)/15ml
Product Code: TSO 7500
Other descriptive name: Suspension of 7500 embryonated, viable TSO/15ml
Dr. Falk Pharma GmbHNULLNot RecruitingFemale: yes
Male: yes
400Phase 2Czech Republic;Denmark;Austria;Germany;Switzerland