96. Crohn disease Clinical trials / Disease details


Clinical trials : 2,400 Drugs : 1,391 - (DrugBank : 267) / Drug target genes : 170 - Drug target pathways : 215

  
9 trials found
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1NCT03747718
(ClinicalTrials.gov)
December 1, 20228/3/2018Randomized Trial Comparing Single vs. Maintenance Fecal Microbiota Transplant for Refractory Crohn's Disease in ChildrenA Study for Evaluation of Clinical Response to Single vs. Maintenance Fecal Microbiota Transplantation in Pediatric Patients With Refractory Crohn's DiseaseCrohn DiseaseBiological: Fecal Microbiota Transplantation;Other: PlaceboStanford UniversityNULLNot yet recruiting2 Years25 YearsAll30Phase 1United States
2NCT04997733
(ClinicalTrials.gov)
September 22, 20215/7/2021Fecal Microbiota Transplantation in Crohn's Disease as Relay After Anti-TNF WithdrawalFecal Microbiota Transplantation in Crohn's Disease as Relay After Anti-TNF WithdrawalCrohn DiseaseDrug: Fecal Microbiota Transplantation (FMT);Drug: Sham-transplantation (placebo)Assistance Publique - Hôpitaux de ParisCRB-HUEP;Institut National de la Santé Et de la Recherche Médicale, FranceRecruiting18 Years74 YearsAll150Phase 3France
3NCT04970446
(ClinicalTrials.gov)
August 1, 202118/7/2021The MIRO II Study: Microbial Restoration in Inflammatory Bowel DiseasesThe MIRO II Study: Microbial Restoration in Inflammatory Bowel DiseasesFecal Microbiota Transplantation;Crohn Disease;Inflammatory Bowel Diseases;MicrobiomeDrug: Antibiotics;Dietary Supplement: Dietician designed diet;Drug: FMT;Other: PlaceboSt Vincent's Hospital MelbourneThe Queen Elizabeth Hospital;BiomeBank Adelaide;The University of Queensland;Monash UniversityNot yet recruiting18 Years70 YearsAll120Phase 2/Phase 3NULL
4EUCTR2019-003816-29-FR
(EUCTR)
16/12/201914/10/2019Fecal microbiota transplantation in Crohn’s disease as relay after anti-TNF withdrawalFecal microbiota transplantation in Crohn’s disease as relay after anti-TNF withdrawal - MIRACLE Adult patients with Crohn’s disease diagnosed for at least 6 months and healthy volunteers donors
MedDRA version: 20.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders ;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: Fecal microbiota
Product Name: Fecal microbiota
ASSISTANCE PUBLIQUE -HOPITAUX DE PARIS (AP-HP)NULLAuthorised-recruitment may be ongoing or finished Female: yes
Male: yes
200 Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): yes Therapeutic use (Phase 4): noFrance
5NCT03078803
(ClinicalTrials.gov)
March 28, 201712/1/2017Fecal Transplant for Crohn's DiseaseA Prospective Multicenter Randomized Controlled Trial Comparing Fecal Microbiota Transplantation (FMT) to Placebo in the Treatment of Mild to Moderate Crohn's DiseaseCrohn DiseaseBiological: Fecal Microbiota Transplant (FMT);Biological: PlaceboUniversity of AlbertaUniversity of Calgary;McMaster UniversityRecruiting18 YearsN/AAll126Phase 2Canada
6NCT02575040
(ClinicalTrials.gov)
May 20156/10/2015Efficacy of Fecal Microbiota Transplantation for Inflammatory Bowel DiseaseEfficacy of Fecal Microbiota Transplantation for Refractory Inflammatory Bowel DiseaseUlcerative Colitis;Crohn Disease;Constipation (Excl Faecal Impaction)Biological: Fecal microbiota transplantationGulhane Military Medical AcademyNULLRecruiting18 YearsN/ABoth60Phase 3Turkey
7NCT02335281
(ClinicalTrials.gov)
January 20157/1/2015Standardized Fecal Microbiota Transplantation for Inflammatory Bowel DiseaseEfficacy, Durability and Safety of Standardized Fecal Microbiota Transplantation for Severe Inflammatory Bowel DiseaseInflammatory Bowel Disease;Ulcerative Colitis;Crohn's DiseaseProcedure: FMT;Drug: MesalazineYanling WeiNULLRecruiting16 Years70 YearsBoth40Phase 2China
8NCT02199561
(ClinicalTrials.gov)
July 201422/7/2014Fecal Microbiota Transplantation (FMT) in the Management of Active Crohn's DiseaseA Prospective, Single Center, Open Label Trial of Fecal Microbiota Transplantation (FMT) in the Management of Active Crohn's DiseaseCrohn's DiseaseBiological: Fecal Microbiota TransplantUniversity of AlbertaNULLCompleted18 Years65 YearsBoth3Phase 1/Phase 2Canada
9NCT02108821
(ClinicalTrials.gov)
March 201421/3/2014Fecal Microbiota Transplantation in Pediatric PatientsA Study of Fecal Microbiota Transplantation in Pediatric Patients With Relapsed Inflammatory Bowel Disease.Inflammatory Bowel Diseases (IBD);Crohn's Disease (CD);Ulcerative Colitis (UC)Biological: Fecal Microbiota Transplantation (FMT)Children's Mercy Hospital Kansas CityUniversity of Pittsburgh;Stanford UniversityCompleted2 Years22 YearsAll23Phase 1United States