96. Crohn disease Clinical trials / Disease details

Clinical trials : 2,400 / Drugs : 1,391 - (DrugBank : 267) / Drug target genes : 170 - Drug target pathways : 215

35 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2018-004346-42-HU (EUCTR)	15/10/2021	31/01/2020	A Study of the Efficacy and Safety of Brazikumab in Participants with Moderately to Severely Active ...	A 52-Week, Multicenter, Randomized, Double-blind, Placebo and Active-Controlled, Operationally Seaml ...	Crohn's Disease MedDRA version: 20.0;Level: LLT;Classification code 10011402;Term: Crohn's disease ( ...	Product Name: Brazikumab Product Code: MEDI2070 INN or Proposed INN: BRAZIKUMAB Other descriptive name: ...	AstraZeneca AB	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	553	Phase 2;Phase 3	United States;Czechia;Taiwan;Slovakia;Spain;Ukraine;Austria;Israel;Russian Federation;United Kingdom ...
2	EUCTR2018-004346-42-IT (EUCTR)	03/09/2020	24/05/2021	An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Act ...	A 52-Week, Multicenter, Randomized, Double-blind, Double-dummy, Placebo and Active-controlled, Opera ...	Crohn's Disease MedDRA version: 20.0;Level: LLT;Classification code 10011402;Term: Crohn's disease ( ...	Product Name: Brazikumab Product Code: [Anti-Interleukin-23 Immunoglobulin G2 (IgG2) Huma INN or Propo ...	ALLERGAN LIMITED	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	2000	Phase 2;Phase 3	United States;Czechia;Spain;Ukraine;Austria;Israel;Russian Federation;United Kingdom;Italy;France;Cz ...
3	EUCTR2018-004346-42-AT (EUCTR)	18/06/2020	21/01/2020	A study of the Efficacy and Safety of Brazikumab in Participants with Moderately to Severly Active C ...	A 52-Week, Multicenter, Randomized, Double-blind, Double-dummy, Placebo and Active-controlled, Opera ...	Crohn's Disease MedDRA version: 20.0;Level: LLT;Classification code 10011402;Term: Crohn's disease ( ...	Product Name: Brazikumab Product Code: MEDI2070 INN or Proposed INN: BRAZIKUMAB Other descriptive name: ...	Astrazeneca AB	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	600	Phase 2;Phase 3	United States;Czechia;Taiwan;Slovakia;Spain;Ukraine;Austria;Israel;Russian Federation;United Kingdom ...
4	EUCTR2018-004346-42-BG (EUCTR)	28/05/2020	08/01/2020	An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Act ...	A 52-Week, Multicenter, Randomized, Double-blind, Double-dummy, Placebo and Active-controlled, Opera ...	Crohn's Disease MedDRA version: 20.0;Level: LLT;Classification code 10011402;Term: Crohn's disease ( ...	Product Name: Brazikumab Product Code: Anti-Interleukin-23 Immunoglobulin G2 (IgG2) Human INN or Propo ...	Allergan Ltd.	NULL	Not Recruiting			Female: yes Male: yes	2000	Phase 2;Phase 3	United States;Spain;Ukraine;Austria;Israel;Russian Federation;United Kingdom;Italy;France;Czech Repu ...
5	EUCTR2018-004346-42-RO (EUCTR)	19/05/2020	18/03/2022	An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Act ...	A 52-Week, Multicenter, Randomized, Double-blind, Double-dummy, Placebo and Active-controlled, Opera ...	Crohn's Disease MedDRA version: 20.0;Level: LLT;Classification code 10011402;Term: Crohn's disease ( ...	Product Name: Brazikumab Product Code: Anti-Interleukin-23 Immunoglobulin G2 (IgG2) Human INN or Propo ...	Allergan Ltd.	NULL	Not Recruiting			Female: yes Male: yes	2000	Phase 2;Phase 3	United States;Czechia;Spain;Ukraine;Austria;Israel;Russian Federation;United Kingdom;Italy;France;Cz ...
6	EUCTR2018-004346-42-BE (EUCTR)	15/04/2020	03/03/2020	An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Act ...	A 52-Week, Multicenter, Randomized, Double-blind, Double-dummy, Placebo and Active-controlled, Opera ...	Crohn's Disease MedDRA version: 20.0;Level: LLT;Classification code 10011402;Term: Crohn's disease ( ...	Product Name: Brazikumab Product Code: Anti-Interleukin-23 Immunoglobulin G2 (IgG2) Human INN or Propo ...	Allergan Ltd.	NULL	Not Recruiting			Female: yes Male: yes	2000	Phase 2;Phase 3	United States;Spain;Ukraine;Austria;Russian Federation;Israel;Italy;United Kingdom;France;Czech Repu ...
7	EUCTR2018-004346-42-CZ (EUCTR)	24/03/2020	22/01/2020	A Study of the Efficacy and Safety of Brazikumab in Participants with Moderately to Severely Active ...	A 52-Week, Multicenter, Randomized, Double-blind, Placebo and Active-Controlled, Operationally Seaml ...	Crohn's Disease MedDRA version: 20.0;Level: LLT;Classification code 10011402;Term: Crohn's disease ( ...	Product Name: Brazikumab Product Code: MEDI2070 INN or Proposed INN: BRAZIKUMAB Other descriptive name: ...	AstraZeneca AB	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	221	Phase 2;Phase 3	United States;Czechia;Taiwan;Slovakia;Spain;Ukraine;Austria;Russian Federation;Israel;United Kingdom ...
8	EUCTR2018-004346-42-ES (EUCTR)	26/12/2019	11/11/2019	An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Act ...	A 52-Week, Multicenter, Randomized, Double-blind, Double-dummy, Placebo and Active-controlled, Opera ...	Crohn's Disease MedDRA version: 20.0;Level: LLT;Classification code 10011402;Term: Crohn's disease ( ...	Product Name: Brazikumab Product Code: Anti-Interleukin-23 Immunoglobulin G2 (IgG2) Human INN or Propo ...	Allergan Ltd.	NULL	Not Recruiting			Female: yes Male: yes	2000	Phase 2;Phase 3	United States;Serbia;Slovakia;Spain;Ukraine;Austria;Russian Federation;Israel;United Kingdom;Italy;F ...
9	EUCTR2018-004346-42-DE (EUCTR)	10/12/2019	17/06/2019	A Study of the Efficacy and Safety of Brazikumab in Participants with Moderately to Severely Active ...	A 52-Week, Multicenter, Randomized, Double-blind, Placebo and Active-Controlled, Operationally Seaml ...	Crohn's Disease MedDRA version: 20.0;Level: LLT;Classification code 10011402;Term: Crohn's disease ( ...	Product Name: Brazikumab Product Code: MEDI2070 INN or Proposed INN: BRAZIKUMAB Other descriptive name: ...	AstraZeneca AB	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	553	Phase 2;Phase 3	Belgium;Poland;Bulgaria;South Africa;Germany;China;Korea, Republic of;Canada;Hungary;Czech Republic; ...
10	EUCTR2018-004346-42-FR (EUCTR)	05/11/2019	10/07/2019	An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Act ...	A 52-Week, Multicenter, Randomized, Double-blind, Double-dummy, Placebo and Active-controlled, Opera ...	Crohn's Disease MedDRA version: 20.0;Level: LLT;Classification code 10011402;Term: Crohn's disease ( ...	Product Name: Brazikumab Product Code: Anti-Interleukin-23 Immunoglobulin G2 (IgG2) Human INN or Propo ...	Allergan Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	2000	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	Serbia;United States;Slovakia;Spain;Ukraine;Austria;Russian Federation;Israel;Italy;United Kingdom;F ...

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