96. Crohn disease Clinical trials / Disease details

Clinical trials : 2,400 / Drugs : 1,391 - (DrugBank : 267) / Drug target genes : 170 - Drug target pathways : 215

206 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05043870 (ClinicalTrials.gov)	April 1, 2022	2/9/2021	Combined Immunosuppression for Pediatric Crohn's Disease	Combination Therapy of Infliximab and Immunosuppressives for Pediatric Crohn's Disease	Crohn Disease;Infliximab;Immunosuppression;Children, Only	Drug: Infliximab and immunosuppressives;Drug: Infliximab	Children's Hospital of Fudan University	NULL	Not yet recruiting	2 Years	18 Years	All	40	Phase 4	NULL
2	NCT04530877 (ClinicalTrials.gov)	January 1, 2022	24/8/2020	Exclusive Enteral Nutrition vs. Infliximab in Chinese CD Patients	Comparative Effectiveness of Exclusive Enteral Nutrition and Infliximabin Chinese Children With Acti ...	Crohn's Disease;Exclusive Enteral Nutrition;Infliximab;Mucosal Healing	Biological: Infliximab;Dietary Supplement: Exclusive Enteral Nutrition	Children's Hospital of Fudan University	NULL	Not yet recruiting	1 Year	18 Years	All	80	Phase 4	NULL
3	EUCTR2020-001811-26-BE (EUCTR)	18/11/2021	22/07/2021	IBD under control with less medication	De-escalation of anti-TNF therapy in adolescents and young adults with IBD with tight faecal calprot ...	Crohn's disease, ulcerative colitis;Therapeutic area: Diseases [C] - Digestive System Diseases [C06] ...	Trade Name: Remicade INN or Proposed INN: INFLIXIMAB Trade Name: Flixabi INN or Proposed INN: INFLIXIMA ...	University Medical Center Groningen	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	148	Phase 4	Belgium;Netherlands
4	NCT04835506 (ClinicalTrials.gov)	November 1, 2021	5/4/2021	Proactive IFX Optimization vs SOC in Patients With CD	Proactive InfliximabOptimization Using a Pharmacokinetic Dashboard Versus Standard of Care in Patien ...	Crohn Disease	Drug: Infliximab	Beth Israel Deaconess Medical Center	The Leona M. and Harry B. Helmsley Charitable Trust;Icahn School of Medicine at Mount Sinai	Recruiting	16 Years	N/A	All	196	Phase 4	United States
5	NCT05072782 (ClinicalTrials.gov)	October 15, 2021	18/8/2021	Management of Moderate POstoperative Recurrence in Crohn's Disease: a randoMizEd contROLled Trial of ...	Management of Moderate POstoperative Recurrence in Crohn's Disease: a randoMizEd contROLled Trial of ...	Crohn Disease	Drug: Infliximab CT-P13;Drug: Immunosuppressors (Thiopurines or Methotrexate)	Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives	Celltrion	Not yet recruiting	18 Years	65 Years	All	360	Phase 4	NULL
6	EUCTR2021-000469-33-NL (EUCTR)	12/10/2021	25/03/2021	Scientific medical research comparing the effectiveness of Infliximabby injection in the abdominal t ...	A Prospective Multicenter Randomized Controlled, Open-label Study to Compare the Efficacy of Subcuta ...	Crohns disease;Therapeutic area: Body processes [G] - Biological Phenomena [G16]	Trade Name: Remsima Product Name: Remsima Product Code: EMEA/H/C/002576 Trade Name: Puri Nethol Product ...	Amsterdam UMC location AMC	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	158	Phase 3;Phase 4	Netherlands
7	EUCTR2019-002942-19-DK (EUCTR)	12/03/2021	05/11/2020	Nordic study of treatment strategy in inflammatory bowel disease	NORDTREATThe Nordic IBD treatment strategy trial – a randomized controlled trial of access to a prot ...	Crohn's disease and Ulcerative colitis MedDRA version: 20.1;Level: LLT;Classification code 10045365; ...	Trade Name: Remicade INN or Proposed INN: INFLIXIMAB Trade Name: Humira INN or Proposed INN: ADALIMUMAB ...	Region Örebro län	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	250	Phase 4	Denmark
8	NCT04646187 (ClinicalTrials.gov)	March 11, 2021	20/11/2020	De-escalation of Anti-TNF Therapy in Inflammatory Bowel Disease	De-escalation of Anti-TNF Therapy in Adolescents and Young Adults With IBD With Tight Faecal Calprot ...	Inflammatory Bowel Diseases;Crohn Disease;Colitis, Ulcerative	Biological: Infliximab;Biological: Adalimumab	University Medical Center Groningen	European Crohn´s and Colitis Organisation;Bühlmann Laboratories AG	Recruiting	12 Years	25 Years	All	148	Phase 4	Belgium;Netherlands;Spain
9	NCT04761952 (ClinicalTrials.gov)	February 13, 2021	14/2/2021	N-3 Polyunsaturated Fatty Acids Prevent Postoperative Recurrence of Crohn's Disease	N-3 Polyunsaturated Fatty Acids Prevent Postoperative Recurrence of Crohn's Disease:a Prospective Ra ...	Inflammatory Bowel Diseases;Crohn Disease;Polyunsaturated Acid Lipidosis	Drug: azathioprine;Drug: infliximab;Drug: N-3 Polyunsaturated Fatty Acids	Sixth Affiliated Hospital, Sun Yat-sen University	NULL	Not yet recruiting	18 Years	80 Years	All	236	N/A	NULL
10	JPRN-UMIN000043165	2021/02/01	31/01/2021	Safety and efficacy of non-medical switching from originator infliximabto infliximabbiosimilar CT-P1 ...	Safety and efficacy of non-medical switching from originator infliximabto infliximabbiosimilar CT-P1 ...	Crohn's disease, Ulcerative colitis, IBDU	witching from originator infliximab to infliximab biosimilar CT-P13	Fukuoka University Chikushi Hospital	NULL	Pending	Not applicable	Not applicable	Male and Female	220	Not selected	Japan

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